A5028208487- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Mental Health Research Topics
- Dementia and Cognitive Impairment Research
- Neural and Behavioral Psychology Studies
- Cognitive Functions and Memory
- Cerebrovascular and Carotid Artery Diseases
- Transcranial Magnetic Stimulation Studies
- EEG and Brain-Computer Interfaces
- Ophthalmology and Eye Disorders
- Ethics and Social Impacts of AI
- Heart Rate Variability and Autonomic Control
- Health disparities and outcomes
- Anesthesia and Neurotoxicity Research
- Alzheimer's disease research and treatments
- Health, Environment, Cognitive Aging
- Human-Automation Interaction and Safety
- Neurotransmitter Receptor Influence on Behavior
- Neural dynamics and brain function
- Olfactory and Sensory Function Studies
- Epilepsy research and treatment
- Neurological Disease Mechanisms and Treatments
- Smoking Behavior and Cessation
- Obsessive-Compulsive Spectrum Disorders
- Acute Ischemic Stroke Management
Beihang University
2019-2025
Southwest University
2016-2025
Beijing Normal University
2024
Recent neurocognitive models propose that the insula serves as a hub of interoceptive awareness system, modulating 2 interplaying systems: The posterior (PI) receives and integrates various signals; these signals are then transmitted to anterior for processing higher-order representations into awareness, where dorsal (dAI) modulates prefrontal self-control system ventral (vAI) amygdala (AMG)-striatal reward-seeking circuit. We sought test this view using multimodal approach. first used...
The neural mechanisms and long-term effects of perceived stress (PS) self-control (SC) on mental health (MH) are not fully understood. This study seeks to investigate the influence PS SC MH identify their correlates using fMRI. A total 817 college students participated in behavioral assessments, including Perceived Stress Scale (PSS), Self-Control (SCS), Mental Health Continuum Short Form (MHC-SF). Among them, 371 underwent fMRI scans calculate zfALFF whole-brain functional connectivity....
Background: Cognitive dysfunction in cerebral small vessel disease (CSVD) patients is associated with white matter hyperintensity (WMH), which demonstrates frequency-dependent correlations brain functional activities. However, the neural mechanisms underlying relationship between these structural and abnormalities cognitive impairment remain unclear. Methods: We recruited 34 CSVD (mean age 63.74 ± 4.85 years, 19 males) 45 age-matched healthy controls 63.69 6.15 15 males). All participants...
Abstract In recent years, electronic cigarettes (e‐cigs) have gained popularity as stylish, safe, and effective smoking cessation aids, leading to widespread consumer acceptance. Although previous research has explored the acute effects of combustible or nicotine replacement therapy on brain functional activities, studies e‐cigs been limited. Using fNIRS, we conducted graph theory analysis resting‐state connectivity 61 male abstinent smokers both before after vaping e‐cigs. And performed...
Abstract White matter abnormalities represent early neuropathological events in neurodegenerative diseases such as Alzheimer's disease (AD), investigating these white alterations would likely provide valuable insights into pathological changes over the course of AD. Using a novel mathematical framework called “Director Field Analysis” (DFA), we investigated geometric microstructural properties (i.e., splay, bend, twist, and total distortion) orientation fibers AD, amnestic mild cognitive...
Abstract The nondemented old–old over the age of 80 comprise a rapidly increasing population group; they can be regarded as exemplars successful aging. However, our current understanding aging in advanced and its neural underpinnings is limited. In this study, we measured microstructural network-based topological properties brain white matter using diffusion-weighted imaging scans 419 community-dwelling older participants. participants were further divided into 230 young–old (between 72 79,...
Aging involves cognitive decline and prominent alterations in brain activity. Electroacupuncture (EA), a traditional Chinese medicine approach, is demonstrated to be effective improving function of older adults. However, the specific neural mechanism underlying this modulation effect remains unclear. In study, we used functional magnetic resonance imaging (fMRI) investigate whether EA could improve performance community-dwelling adults these potential improvements are associated with...
Abstract Proactive inhibition is a critical ability for smokers who seek to moderate or quit smoking. It allows them pre‐emptively refrain from seeking and using nicotine products, especially when facing salient smoking cues in daily life. Nevertheless, there limited knowledge on the impact of behavioural neural aspects proactive inhibition, with withdrawal. Here, we bridge this gap. To end, recruited 26 complete stop‐signal anticipant task (SSAT) two separate sessions: once neutral cue...
As one of the most serious public health problems that extract a high toll on individuals and society as whole, substance abuse/addiction has attracted much attention from both researchers public. According to DSM-5, addiction is chronically relapsing psychiatric disorder been characterized by compulsion seek use drugs, loss control in limiting intake despite negative consequences. However, more than 80% with fail treatment, perhaps reflecting their cognitive function impairments. Previous...
Abstract Non-invasive brain stimulations have drawn attention in remediating memory decline older adults. However, it remains unclear regarding the cognitive and neural mechanisms underpinning neurostimulation effects on rehabilitation. We evaluated intervention of 2-weeks neurostimulations (high-definition transcranial direct current stimulation, HD-tDCS, electroacupuncture, EA versus controls, CN) activities functional connectivity during a working task normally adults (age 60+, n = 60)....
Objective: To analyze the correlation between white matter integrity and spatial navigation impairment in patients with mild cognitive (MCI). Methods: A total of 27 MCI subjects 24 healthy controls were enrolled from Affiliated Drum Tower Hospital Nanjing University Medical School May 2015 to February 2016, who underwent 3.0 T MRI scan 2D-computer version test.DTI preprocessing tract-based statistics (TBSS) performed by PANDA.Two sample t-test partial coefficients investigate impairments...
Background: Compensation has been proposed as a mechanism to explain how individuals in extreme old age remain able maintain normal cognitive functioning. Previous studies have provided evidence on the role of increasing functional connectivity compensatory for age-related white matter damage. However, we lack direct investigation into these mechanisms contribute preservation cognition very population.Methods: We examined cohort near-centenarians and centenarians without dementia (aged...