Guangrui Zhao

ORCID: 0000-0003-0408-1090
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About
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Research Areas
  • Neurological disorders and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Traumatic Brain Injury Research
  • Transcranial Magnetic Stimulation Studies
  • Psychosomatic Disorders and Their Treatments
  • Epilepsy research and treatment
  • Cardiac Arrest and Resuscitation
  • Functional Brain Connectivity Studies
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Bacterial Infections and Vaccines
  • Botulinum Toxin and Related Neurological Disorders
  • Neuroscience and Neural Engineering
  • Pharmacological Effects and Toxicity Studies
  • Neuroscience and Neuropharmacology Research

Tianjin Medical University
2022-2025

Lu'an First People's Hospital
2022-2024

Anhui Medical University
2022-2024

OBJECTIVE A decline in verbal fluency (VF) after subthalamic stimulation has been frequently reported; however, the reasons and mechanisms for this remain unclear. This study investigated impact of on semantic VF decline, analyzed associated factors, uncovered relevant by exploring local network effects. METHODS Included were 78 patients with Parkinson’s disease who categorized into either stable group (n = 32) or decliner 46) based whether decreased stimulation. The baseline follow-up...

10.3171/2024.12.jns241574 article EN Journal of neurosurgery 2025-04-01

Background. Prolonged disorders of consciousness (pDOC) are common in neurology and place a heavy burden on families society. This study is aimed at investigating the characteristics brain connectivity patients with pDOC based quantitative EEG (qEEG) extending new direction for evaluation pDOC. Methods. Participants were divided into control group (CG) DOC by presence or absence underwent magnetic resonance imaging (MRI) T1 three-dimensional magnetization prepared rapid acquisition gradient...

10.1155/2023/4142053 article EN cc-by Neural Plasticity 2023-04-18

Our objective is to analyze the difference of microelectrode recording (MER) during awake and asleep subthalamic nucleus deep brain stimulation (STN-DBS) for Parkinson’s disease (PD) necessity MER “Asleep DBS” under general anesthesia (GA). The differences in MER, target accuracy, prognosis different methods were analyzed. Additionally, length was compared with postoperative electrode by reconstruction measurement. two groups 5.48 ± 1.39 mm local (LA) group 4.38 1.43 GA group, a statistical...

10.3390/brainsci12111469 article EN cc-by Brain Sciences 2022-10-29

To explore the relevant factors that affect efficacy of consciousness-regaining therapy (CRT)for prolonged disorder consciousness(pDOC),a retrospective analysis was conducted on case data 114 patients with pDOC admitted to department functional neurosurgery Tianjin Huanhu Hospital from January 2019 2022. Basic information cases,data disease assessment, methods, and evaluation were collected. A total grouped compared based at end treatment. Among them, there 61 cases in ineffective group 53...

10.20944/preprints202402.1685.v1 preprint EN 2024-02-29

Abstract Background Currently, the conclusions of studies on subthalamic nucleus (STN) deep brain stimulation (DBS) for improving Parkinson's disease (PD) with depression are inconsistent, and reasons improvement or deterioration remain unclear. Methods The aim was to investigate prognosis PD after bilateral STN‐DBS factors related in depression. local network effects DBS (DPD) were further explored based volume tissue activation (VTA). study analyzed 80 primary patients who had undergone...

10.1002/mdc3.14195 article EN Movement Disorders Clinical Practice 2024-09-11
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