A5015742722- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Oral and Maxillofacial Pathology
- TGF-β signaling in diseases
- Lanthanide and Transition Metal Complexes
- Chromatin Remodeling and Cancer
- Hedgehog Signaling Pathway Studies
- Bone Metabolism and Diseases
- Genomics and Chromatin Dynamics
- Radioactive element chemistry and processing
- Metal-Organic Frameworks: Synthesis and Applications
- Head and Neck Surgical Oncology
- Cyclopropane Reaction Mechanisms
- Chemical Synthesis and Characterization
- Vascular Tumors and Angiosarcomas
- Soft tissue tumor case studies
- Inorganic Fluorides and Related Compounds
- Synthesis and Reactivity of Heterocycles
- Osteoarthritis Treatment and Mechanisms
- Cancer-related gene regulation
- Histiocytic Disorders and Treatments
- dental development and anomalies
- Tumors and Oncological Cases
- Click Chemistry and Applications
University of Alabama at Birmingham
2020-2024
University of Alabama
2019-2022
Eu-DOBDC metal–organic frameworks (MOFs) have demonstrated capabilities in the adsorption of acid gases, indicating that other rare earth (RE)-DOBDC MOFs are promising candidates for similar applications. To investigate entire suite RE-DOBDC MOFs, density functional theory (DFT) simulations bulk periodic and cluster structure models were used to predict gas adsorption. Cluster M(L)3, L = OOCH–, BDC–, DOBDC–, calculate binding enthalpies NO2, SO2, H2O directly metal sites, whereas DFT...
Deletion of Runx2 gene in proliferating chondrocytes results complete failure endochondral ossification and perinatal lethality. We reported recently that mice with deletion specifically hypertrophic (HCs) using the Col10a1-Cre transgene survive exhibit enlarged growth plates due to decreased HC apoptosis cartilage resorption. Bulk chondrogenesis occurs postnatally, however, role HCs during postnatal is unknown. Despite limb dwarfism, adult homozygous (Runx2HC/HC) showed a significant...
Soft-Lewis basic complexants that facilitate chemoselective separation of the minor actinides from lanthanides are critical to closure nuclear fuel cycle. Complexants modulate covalent orbital interactions with relevant metals interest can desired outcomes in liquid-liquid separation, allowing for further transmutative processes decrease issues related storage spent energy and weapons production. Synthesis previously unexplored scaffolds seeks improve performance over benchmark complexants....
Chromatin remodeling, specifically the tissue-specific regulation in mineralized tissues, is an understudied avenue of gene regulation. Here we show that Baf45a and Baf45d, two Baf45 homologs belong to ATPase-dependent SWI/SNF chromatin remodeling complex, preferentially expressed osteoblasts odontoblasts compared Baf45b Baf45c. Recently, biochemical studies revealed BAF45A associates with Polybromo-associated BAF (PBAF) complex. However, BAF45D subunit belongs polymorphic canonical...
The effect of frustrated Lewis donors on metal selectivity between actinides and lanthanides was studied using a series novel organic ligands. Structures thermodynamic energies were predicted in the gas phase, water, butanol 9-coordinate, explicitly solvated (H2O) Eu, Gd, Am, Cm +III oxidation state as reactants formation complexes with 2-(6-[1,2,4]-triazin-3-yl-pyridin-2-yl)-1H-indole (Core 1), 3-[6-(2H-pyrazol-3-yl)pyridin-2-yl]-1,2,4-triazine 2), several derivatives. These complexations...
Central odontogenic fibromas (COF) are rare, benign tumors derived from dental mesenchymal tissue that may occur in the maxilla or mandible. This report describes primary and recurrent COF mandible of a patient with nevoid basal cell carcinoma syndrome (NBCCS). A 36-year-old African American male presented its recurrence 17 months later. Tissue pieces were obtained both occurrences IRB-approved signed consent. Collected dissected; one portion was formalin-fixed paraffin-embedded, other...