A5055142733- Health Systems, Economic Evaluations, Quality of Life
- Global Cancer Incidence and Screening
- Patient-Provider Communication in Healthcare
- Ethics in Clinical Research
- Multiple Sclerosis Research Studies
- Cancer survivorship and care
- BRCA gene mutations in cancer
- Endometriosis Research and Treatment
- Mental Health and Patient Involvement
- Pharmaceutical industry and healthcare
- Biomedical Ethics and Regulation
- Health Literacy and Information Accessibility
- Pharmaceutical Economics and Policy
- Estrogen and related hormone effects
- Ethics in medical practice
- Childhood Cancer Survivors' Quality of Life
- Economic and Financial Impacts of Cancer
- Migraine and Headache Studies
- Nosocomial Infections in ICU
- Credit Risk and Financial Regulations
- Breast Cancer Treatment Studies
- Uterine Myomas and Treatments
- Menopause: Health Impacts and Treatments
- Colorectal Cancer Screening and Detection
- Palliative Care and End-of-Life Issues
Mario Negri Institute for Pharmacological Research
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2024
St Thomas' Hospital
2018
Istituto Superiore di Sanità
2006-2010
Intesa Sanpaolo (Italy)
2009
Europa Donna
1998-2006
Italian Medicines Agency
2006
Istituto Nazionale di Fisica Nucleare, Sezione di Trieste
2002-2004
Scuola Internazionale Superiore di Studi Avanzati
2002-2004
University of Modena and Reggio Emilia
2003
Introduction: No prior study of endometriosis has investigated the psychological impact having asymptomatic versus with pelvic pain in a systematic way. This aimed at examining on quality life, anxiety and depression by comparing endometriosis, pain, healthy, pain-free controls. The different types was also tested.Methods: One hundred ten patients surgically diagnosed (78 32 without symptoms) 61 healthy controls completed two psychometric tests assessing depression. Endometriosis...
The PGWBI is a 22-item health-related Quality of Life (HRQoL) questionnaire developed in US which produces self-perceived evaluation psychological well-being expressed by summary score. has been validated and used many countries on large samples the general population specific patient groups. Recently study was carried out Italy to reduce number items original questionnaire, yielding creation shorter version (PGWB-S). purpose present paper describe methods adopted report discuss relevance...
To compare the effect of a levonorgestrelreleasing intrauterine device with that endometrial resection on menstrual bleeding, patient satisfaction, and quality life in menorrhagic women during 12 months followup. Seventy premenopausal dysfunctional uterine bleeding were enrolled prospective, open, parallel-group, controlled trial. They randomized to either insertion an system releasing 20 μg/day levonorgestrel (n = 35) or 35). The evaluated at baseline, thereafter, was assessed monthly...
Background Hemoglobin concentrations slightly below the lower limit of normal are a common laboratory finding in elderly, but scant evidence is available on actual occurrence mild anemia despite its potential effect health. The objectives this study were to estimate prevalence and incidence grade assess frequency types elderly.Design Methods This was prospective, population-based all residents 65 years or older Biella, Italy.Results Blood test results for analysis from 8,744 elderly....
In 724 critically ill patients who had received prolonged (> 24 h) ventilatory assistance since admission to the ward, we analyzed relationship between artificial support and pulmonary infection. Two different approaches were used. The first, plotting incidence of pneumonia versus duration support, confirms previous data: rises from 5% in receiving one day respiratory 68.8% more than 30 days. second approach, same data computed as an actuarial life table with onset terminal event. This...
Screening programmes are often actively promoted to achieve high coverage, which may result in unrealistic expectations. We examined women's understanding of the likely benefits mammography screening.Telephone survey random samples female population aged > or =15 years US, UK, Italy, and Switzerland using three closed questions on expected screening.A total 5964 women were contacted 4140 (69%) participated. Misconceptions widespread: a majority believed that screening prevents reduces risk...
BACKGROUND: Interest in measuring health-related quality of life (HRQoL) has increased together with an awareness that such humanistic outcomes require valid and reliable measures. In the last decade short, simple multidimensional generic disease-specific questionnaires have been developed. Among several available, Short Form 36 Items Health Survey (SF-36) was translated validated languages, applied to different settings diseases. METHODS: Within framework a larger, prospective, multicentre...
Background In the elderly persons, hemoglobin concentrations slightly below lower limit of normal are common, but scant evidence is available on their relationship with significant health indicators. The objective present study was to cross-sectionally investigate association mild grade anemia cognitive, functional, mood, and quality life (QoL) variables in community-dwelling persons. Methods Among 4,068 eligible individuals aged 65–84 years, all persons (n = 170) a randomly selected sample...
<h3>OBJECTIVES</h3> Health related quality of life (HRQOL) inventories are multi-dimensional measures patient-centred health status developed for clinical research. The MS 54 (MSQOL-54) is an MS-specific HRQOL inventory originally devised English speaking patients. It consists a core measure, the 36-item short form survey (SF-36) previously adapted into Italian, and 18 additional items exploring domains relevant to patients with (MS-18 module). authors translated culturally Italian MS-18...
SF-12 is a generic short form health survey, developed in the USA from original SF-36. It produces two summary measures evaluating physical and mental self-perceived that are interchangeable with those has been successfully tested nine Western European countries on large samples of general population, where it proved its brevity, comprehensiveness, reliability, validity cross-cultural applicability. The present analysis directly assesses for first time various Italian settings, including...
Measurement of quality life (QOL) in cancer clinical trials has increased recent years as more groups realize the importance such endpoints. A key problem been missing data. Some QOL data may unavoidably be missing, for example when patients are too ill to complete forms. Other important sources potentially avoidable and can broadly divided into three categories: (i) methodological factors; (ii) logistic administrative (iii) patient-related factors. Logistic factors, example, staff...
We have developed and tested an Italian version of the Migraine Disability Assessment (MIDAS) questionnaire, established instrument for assessing headache-related disability. A multistep process was used to translate adapt questionnaire into Italian, which then on 109 migraine without aura patients, 86 (78.9%) whom completed form a second time 21 days later. Overall MIDAS score had good test–retest reliability (Spearman's correlation 0.77), closely similar that found in English-speaking...
Mild anemia is a frequent laboratory finding in the elderly usually disregarded everyday practice as an innocent bystander. The aim of present population-based study was to prospectively investigate association mild grade with hospitalization and mortality.A prospective all 65 84 year old residents Biella, Italy performed between 2003 2007. Data from total 7,536 blood tests were available estimate mortality; full health information evaluate health-related outcomes for 4,501 these subjects....
The Internet is increasingly prominent as a source of health information for people with multiple sclerosis (MS). But there has been little exploration the needs, experiences and preferences MS integrating treatment into decision making, in context searching on Internet. This was aim our study.Sixty participants (51 MS; nine family members) took part focus group or online forum. They were asked to describe how they find assess reliable (particularly online) this changes over time. Thematic...
Abstract The past decade has seen extraordinary increase in worldwide availability of and access to several large multiple sclerosis (MS) databases registries. MS registries represent powerful tools provide meaningful information on the burden, natural history, long-term safety effectiveness treatments. Moreover, patients, physicians, industry, policy makers have an active interest real-world observational studies based register data, as they potential answer questions that are most relevant...
<h3>Background and Objectives</h3> Several studies have assessed risk factors associated with the severity of COVID-19 outcomes in people multiple sclerosis (PwMS). The potential role disease-modifying therapies (DMTs) demographic clinical on acquiring SARS-CoV-2 infection has not been evaluated so far. objective this study was to assess contracting PwMS by using data collected Italian MS Register (IMSR). <h3>Methods</h3> A case-control (1:2) set up. Cases included a confirmed diagnosis...