A5044014215- Urinary Bladder and Prostate Research
- Prostate Cancer Diagnosis and Treatment
- Immune Response and Inflammation
- Phytoestrogen effects and research
- Tribology and Lubrication Engineering
- Prostate Cancer Treatment and Research
- Immunotherapy and Immune Responses
- Urologic and reproductive health conditions
Zhongnan Hospital of Wuhan University
2022-2025
Wuhan University
2022-2025
Background and objects Benign prostatic hyperplasia (BPH) is a common disease that impairs the life quality of elderly men. The close relationship BPH diabetes has been generally established, however, exact molecular mechanism remains unclear. Midline-1 (MID1) an E3 ubiquitin ligase belonging to Tripartite Motif family its involvement in initiation progression many diseases, such as diabetic kidney well accepted. This study aims illuminate potential impact high glucose (HG) on cells...
C-X-C motif chemokine ligand 13 (CXCL13), a member of the CXC subtype in superfamily, affects numerous biological processes various types cells and progress great number clinical diseases. The purpose current study was to reveal internal mechanism between CXCL13 benign prostatic hyperplasia (BPH).Human serum, prostate tissues human cell lines (BPH-1, WPMY-1) were utilized. effect recombinant (rHuCXCL13) protein influences knockdown/overexpression on two studied. Rescue experiments by...