- Toxic Organic Pollutants Impact
- Nuclear and radioactivity studies
- Per- and polyfluoroalkyl substances research
- Pesticide and Herbicide Environmental Studies
- Air Quality and Health Impacts
- Environmental Conservation and Management
- Chemical Safety and Risk Management
- Risk and Safety Analysis
- Environmental Toxicology and Ecotoxicology
- Pesticide Residue Analysis and Safety
- Insect and Pesticide Research
- Chromium effects and bioremediation
- Analytical chemistry methods development
- Data-Driven Disease Surveillance
- Ecosystem dynamics and resilience
- Healthcare and Environmental Waste Management
- Environmental remediation with nanomaterials
- Effects and risks of endocrine disrupting chemicals
- Recycling and Waste Management Techniques
- Immunotoxicology and immune responses
- Agricultural safety and regulations
- Wildlife Conservation and Criminology Analyses
- Pharmacogenetics and Drug Metabolism
- Carcinogens and Genotoxicity Assessment
- Animal testing and alternatives
Integral Consulting (United States)
2007-2022
North Carolina State University
1989
Perfluorohexanoic acid (PFHxA) is a short-chain, six-carbon perfluoroalkyl (PFAA) and primary impurity, degradant, metabolite associated with the short-chain fluorotelomer-based chemistry used globally today. The transition to products as cornerstone in replacement fluorochemistry has raised questions regarding potential human health risks exposure substances therefore, PFHxA. Here, we present critical review of data relevant such risk assessment, including epidemiological studies vivo vitro...
Perfluorohexanoic acid (PFHxA) is a short-chain, six-carbon PFAA and primary impurity, degradant, metabolite associated with the short-chain fluorotelomer-based chemistry used in United States, Europe Japan today. With shift towards chemistry, uncertainties remain regarding human health risks current exposure levels. Here, we present critical review assessment of data relevant to risk today's chemistry. Human biomonitoring surveys indicate that PFHxA infrequently detected environment as well...
At the time of this writing, more than 18 million people worldwide are known to have contracted COVID-19, medical condition caused by novel SARS-CoV-2 coronavirus (Johns Hopkins 2020). The World Health Organization confirmed COVID-19 outbreak as a global pandemic in March 2020, virus spread rapidly worldwide. end health emergency is not yet sight. Responses crisis from politicians and public officials different countries adapted, with few notable exceptions, evolving epidemiological...
Ecotoxicological benchmarks are used extensively in ecological risk assessment to determine if chemicals present or potentially released the environment pose an threat. No consistent standards currently exist for data quality evaluation of toxicological studies derive ecotoxicological use assessment. This paper outlines a two-phased approach evaluating be benchmark development. First, reviewed their adherence set standardized testing and reporting protocols. Second, once have been...
Abstract Environmental contamination with ionic chromium has been identified as a problem at numerous Superfund and RCRA Corrective Action sites. In many cases, of groundwater to levels above existing standards or criteria may be potential both for direct consumption transport mobile forms areas such basements where it can becontacted. the environment, occurs in two forms: trivalent hexavalent. The form is generally immobile nontoxic; hexavalent toxic. This article first presents extent...
Alpha-hexachlorocyclohexane (alpha-HCH) is one of eight structural isomers that have been used worldwide as insecticides. Although no longer produced or agriculturally in the United States, exposure to HCH continuing concern due legacy usage and persistence environment. The U.S. Environmental Protection Agency (EPA) classifies alpha-HCH a probable human carcinogen provides slope factor 6.3 (mg/kg-day)(-1) for compound, based on hepatic nodules hepatocellular carcinomas observed male mice...
Abstract Although ecological risk assessments (ERAs) and natural resource damage (NRDAs) are performed under different statutory regulatory authorities, primarily the Comprehensive Environmental Response, Compensation Liability Act (CERCLA), as currently practiced, activities typically overlap. ERAs part of response process (typically by US Protection Agency [USEPA]) should be closely coordinated with trustees (‘trustees’) NRDAs. Trustees actively participate in early stages remedial...
Effective environmental management and restoration of urbanized systems such as the Delaware River Estuary requires a holistic understanding relative importance various stressor-related impacts throughout watershed, both historical ongoing. To that end, it is important to involve many stakeholders possible in process develop system for sharing scientific data information, well effective technical tools evaluating disseminating needed make decisions. In this study, we describe preliminary...
In contemporary society, many scientific issues involving toxi-cologists, epidemiologists, and other risk assessment professionals have become the topics of hotly contested legal actions. Nowhere is this more apparent than in toxic tort cases where judgements millions dollars can hinge on expert testimony provided by a toxicologist. Many these involve opinions that not yet entered mainstream thought, thus it becomes necessary for courts to place great deal emphasis reliability science....