A5035869167- Cervical Cancer and HPV Research
- Global Cancer Incidence and Screening
- Endometrial and Cervical Cancer Treatments
- Genital Health and Disease
- Cell Image Analysis Techniques
- bioluminescence and chemiluminescence research
- Colorectal Cancer Screening and Detection
- Colorectal and Anal Carcinomas
- Cancer Risks and Factors
- Pregnancy and preeclampsia studies
- Bacterial biofilms and quorum sensing
- Urological Disorders and Treatments
- Medical and Biological Sciences
- Educational Technology and Optimization
- Nursing Roles and Practices
- Systemic Sclerosis and Related Diseases
- COVID-19 and Mental Health
- linguistics and terminology studies
- Antibiotic Use and Resistance
- Patient-Provider Communication in Healthcare
- 3D Printing in Biomedical Research
- Long-Term Effects of COVID-19
- Plant Ecology and Soil Science
- Microbial bioremediation and biosurfactants
- Environmental DNA in Biodiversity Studies
The University of Texas Southwestern Medical Center
2003-2025
Parkland Health & Hospital System
2006-2025
Southwestern Medical Center
2018-2024
Charité - Universitätsmedizin Berlin
2024
Augusta University
2002
North Shore University Hospital
2002
New York University
2002
University of Tennessee at Knoxville
1994-2001
Oak Ridge National Laboratory
2000
In Brief Objective. To relate aspects of online colposcopic image assessment to the diagnosis grades 2 and 3 cervical intraepithelial neoplasia (CIN 2+). Methods: simulate assessment, we obtained digitized images at enrollment after acetic acid application from 919 women referred for equivocal or minor cytologic abnormalities into ASCUS-LSIL Triage Study. For each, randomly assigned evaluators a pool 20 colposcopists assessed using standardized tool online. We calculated accuracy these...
Abstract The American Society for Colposcopy and Cervical Pathology (ASCCP) Standards recommendations address the role of colposcopy directed biopsy cervical cancer prevention in United States (US). were developed by an expert working group appointed ASCCP's Board Directors. An extensive literature review was conducted supplemented a systematic meta-analysis unpublished data. In addition, survey practicing colposcopists to assess current practice US. Recommendations approved members, final...
To quantify how many patients treated for high-grade cervical dysplasia completed guideline-concordant surveillance. We retrospectively analyzed aged 30-65 (cervical intraepithelial neoplasia 2 or worse) at two PROSPR II METRICS (Population-based Research to Optimize the Screening Process Multi-level Optimization of Cervical Cancer in Diverse Settings & Populations sites) (Massachusetts General Brigham, Parkland Health) from 2010 2019. The primary outcome was receipt negative co-tests after...
Pseudomonas fluorescens HK44 represents the first genetically engineered microorganism approved for field testing in United States bioremediation purposes. Strain harbors an introduced lux gene fused within a naphthalene degradative pathway, thereby allowing this recombinant microbe to bioluminesce as it degrades specific polyaromatic hydrocarbons such naphthalene. The process can therefore be monitored by detection of light. P. was inoculated into vadose zone intermediate-scale,...
Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a severely debilitating condition which markedly restricts activity and function of affected people. Since the beginning COVID-19 pandemic ME/CFS related to post-acute (PACS) can be diagnosed in subset patients presenting with persistent 6 months after mostly mild SARS-CoV-2 infection by fulfillment Canadian Consensus Criteria (CCC 2003). Induction autoimmunity viral mechanism under intensive investigation. In...
In Brief OBJECTIVE: To examine whether preterm birth is related to the loop electrosurgical excision procedure (LEEP) itself or intrinsic women undergoing procedure. METHODS: Rates of birth, defined as births before 37 weeks gestation, well causes were analyzed in LEEP after an index pregnancy. These rates compared with general obstetric population. RESULTS: A total 241,701 delivered singletons at Parkland Hospital between January 1992 and May 2008; these women, 511 previously had undergone...
Importance As US health care systems shift to human papillomavirus (HPV)–based cervical cancer screening, more patients are receiving positive high-risk non–16/18 genotype HPV results and negative for intraepithelial lesion or malignancy (NILM) cytological findings. Risk-based management guidelines recommend 2 consecutive annual return routine screening. Objective To quantify patterns of surveillance testing associated outcomes after an HPV-positive NILM cytologic Design, Setting,...
OBJECTIVE: To describe the proportion of patients with documentation meeting cervical cancer screening exit criteria in medical record and to estimate incidence high-grade precancerous lesions after age 65 years detected by end study period, eligibility. METHODS: We conducted a retrospective analysis who turned 66 old between 2010 2019 at two large health care systems located Dallas, Texas, Boston, Massachusetts, from METRICS (MultilEvel opTimization ceRvIcal Cancer Screening process diverse...
Little is known about cervical cancer screening and results patterns among HIV-infected (HIV+) women in real-world healthcare settings. We characterized two periods of opportunity.Retrospective cohort.US safety-net system Dallas County, Texas.We analyzed data from electronic medical records (EMR) 1490 HIV+ receiving care 2010-2014.At baseline, we categorized a woman's Pap status 15 months prior to index date as under-screened (vs. screened), cytology result (normal vs. abnormal). Then,...
The high prevalence of cervical cancer at safety-net health systems requires careful analysis to best inform prevention and quality improvement efforts. We characterized burden identified opportunities for in a U.S. system.We reviewed tumor registry electronic record (EHR) data women with invasive ages 18+, diagnosed between 2010 2015, large, integrated urban safety-net. developed an algorithm to: (i) classify whether had been engaged care (≥1 clinical encounter 6 months 5 years before...
Liquid-based ThinPrep technology has made reflex human papillomavirus (HPV) DNA testing possible. In the current study, clinical performance of HPV as an adjunct to routine (TPPT) and impact age on various test parameters in a predominantly high-risk, minority population were evaluated retrospectively.Reflex was performed 2114 women with atypical squamous cells undetermined significance (ASCUS) low-grade intraepithelial lesion (LSIL) cytology, using probes for low-risk (LR) high-risk (HR)...
In Brief Objective. This study compared the performance of cervical cytology plus human papilloma virus testing (Pap + HPV) or spectroscopy CS) for identifying high-grade neoplasia in a high-risk population women referred colposcopy. Materials and Methods. Each 113 subjects underwent spectroscopy, thin-layer cytology, HPV testing, colposcopy, biopsy when indicated, and/or endocervical curettage. Evaluable data analysis were collected 102 subjects. Sensitivity specificity calculated both...
To quantify the association between time to colposcopy and risk of subsequent cervical cancer.A longitudinal analysis patients aged 21-79 years with an abnormal cancer test result from health care systems in Texas, Massachusetts, Washington was performed. The outcome a diagnosis 12 months or more after result. primary compared receipt within 3 (91 days less) at 3-12 (92-365 days) no result; post hoc analyses (365 months. Associations were assessed multivariable Cox proportional hazards...
(Abstracted from Obstet Gynecol 2023;142:1125–1134) Recommended testing for cervical cancer includes colposcopy after abnormal Pap or human papillomavirus (HPV) test results. This method is designed to diagnose cancers early and additionally detect precancerous tissue before it becomes cancerous.
Follow-up of abnormal results is essential to cervical cancer screening, but data on adherence follow-up are limited. We describe patterns after screening abnormalities and identify predictors guideline-concordant follow-up.
<div>AbstractBackground:<p>Follow-up of abnormal results is essential to cervical cancer screening, but data on adherence follow-up are limited. We describe patterns after screening abnormalities and identify predictors guideline-concordant follow-up.</p>Methods:<p>We identified the index abnormality (positive human papillomavirus test or atypical squamous cells undetermined significance more severe cytology) among women ages 25 65 years at three US healthcare systems...