A5015459899- Moringa oleifera research and applications
- Phytochemistry and Bioactivity Studies
- Complementary and Alternative Medicine Studies
- Plant Toxicity and Pharmacological Properties
- Phytochemistry and biological activity of medicinal plants
- Pharmacological Effects of Natural Compounds
- Phytochemical compounds biological activities
- Phytochemistry and Biological Activities
- Eicosanoids and Hypertension Pharmacology
- Protein Hydrolysis and Bioactive Peptides
- Biological and pharmacological studies of plants
- Essential Oils and Antimicrobial Activity
- Herbal Medicine Research Studies
- Medicinal plant effects and applications
- Morinda citrifolia extract uses
- Ethnobotanical and Medicinal Plants Studies
- Diverse Scientific Research Studies
- Psidium guajava Extracts and Applications
- Urticaria and Related Conditions
- Piperaceae Chemical and Biological Studies
- Toxin Mechanisms and Immunotoxins
Abbottabad University of Science and Technology
2022
COMSATS University Islamabad
2016-2022
Gomal University
2022
Information Technology University
2016-2019
Abbott (Germany)
2017
Urtica dioica has traditionally been used in the management of cardiovascular disorders especially hypertension. The aim this study was to explore pharmacological base its use Crude methanolic extract U. (Ud.Cr) and fractions (Ud.EtAc, Ud.nHex, Ud.Chl Ud.Aq) were tested vivo on normotensive hypertensive rats under anesthesia for blood pressure lowering effect. In-vitro experiments rat rabbit aortae employed probe vasorelaxation mechanism(s). responses measured using force transducers...
Viscum album has shown inhibitory effect on different smooth muscles but underlying mechanisms in gut and vascular are not well defined. Additionally, the plant also importance managing hyperactive cardiovascular disorders. The current study was aimed to probe a pharmacological base of muscle relaxant V. preparations.V. crude extract (Va. Cr) its ethyl acetate fraction EtAc) were studied using vitro techniques. antispasmodic activity performed isolated rabbit jejunum while vasorelaxant...
Rumex acetosa L. (Polygonaceae) is well known in traditional medicine for its therapeutic efficacy as an antihypertensive.The study investigates antihypertensive potential of crude methanol extract (Ra.Cr) and fractions normotensive hypertensive rat models probes the underlying vascular mechanisms.Ra.Cr were tested vivo on Sprague-Dawley rats under anaesthesia blood pressure lowering effect. In vitro experiments Oryctolagus cuniculus rabbit aortae employed to probe vasorelaxant mechanism.In...
Melia azedarach L. leaves have been traditionally used but not scientifically evaluated for antihypertensive activity. The focus of the present work was to carry out detailed phytochemical profiling and potential methanolic extract subsequent fractions this plant. tandem mass spectrometry-based M. (Ma.Cr) determined in negative ionization mode while molecular networking executed using Global Natural Product Social (GNPS) platform. This study resulted identification 29 compounds including...
Bergenin is a phenolic glycoside that has been reported to be present in some medicinal plants which are traditionally used for their antihypertensive actions. So, bergenin was investigated and vasorelaxant experiments rat model. produced significant fall the mean arterial pressure (MAP) of rats. To explore involvement NO muscarinic receptors, rats were pretreated with L-NAME atropine in-vivo. The did not change significantly effect on MAP excluding NO. Unlike L-NAME, pretreatment reduced...
The current study was aimed to investigate the extracts from Heliotropium strigosum and Trapa bicornis phytochemically for various constituents pharmacologically gastro-intestinal disorders. Phytochemical analysis indicated presence of alkaloids, flavonoids, glycosides tannins in both extracts. In castor oil-induced diarrhea, H. T. bicornis, at 100-1000 mg/kg dose provided protection 10-83% 14-76% respectively. isolated rabbit jejunum preparations, (0.01-5 mg/mL) relaxed spontaneous K+ (80...
This study aimed to explore pharmacological base of the medicinal use Elaeagnus umbellata in cardiovascular diseases.In normotensive and hypertensive rats under anaesthesia, crude extract (Eu.Cr) selected fractions exhibited a fall mean arterial pressure.In isolated rat aortic rings, fractions, L -NAME sensitive endothelium dependent vasodilator effect inhibited K + (80 mM) pre-contractions.In rabbit rings pre-constricted with phenylephrine (1 µM), Eu.Cr induced relaxation high potency...