A5045869696- Pain Mechanisms and Treatments
- Cancer, Stress, Anesthesia, and Immune Response
- Pain Management and Opioid Use
- BRCA gene mutations in cancer
- Neuropeptides and Animal Physiology
- Invertebrate Immune Response Mechanisms
- Pediatric Pain Management Techniques
- Biomedical Ethics and Regulation
- Health Literacy and Information Accessibility
- interferon and immune responses
- Economic and Financial Impacts of Cancer
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuroendocrine regulation and behavior
- Immune Response and Inflammation
- Inflammasome and immune disorders
- Adrenal Hormones and Disorders
- Patient-Provider Communication in Healthcare
- Bone health and treatments
University of Chicago
2024
Duke University
2023
Duke University Hospital
2020-2021
Duke Medical Center
2020-2021
The immune checkpoint inhibitor programmed cell death protein 1 (PD-1) plays a critical role in regulation. Recent studies have demonstrated functional PD-1 expression peripheral sensory neurons, which contributes to neuronal excitability, pain, and opioid analgesia. Here we report function of the central nervous system (CNS), including spinal cord, thalamus, cerebral cortex. Notably, GABA-induced currents dorsal horn thalamic cortical neurons are suppressed by PD-1-neutralizing...
<sec> <title>BACKGROUND</title> NCI-designated cancer centers (NCI-CCs) throughout the U.S. are mandated to translate state-of-the-art research communities and enhance clinical care for patients within their catchment areas. In this era of targeted personalized care, though genetics has been incorporated into centers, it is unknown how these innovations being communicated public served. There particularly limited knowledge surrounding NCI-CCs may integrate patient reported experiences with...
Abstract Since the National Cancer Act established Centers Program in 1971, NCI-designated cancer centers (NCI-CCs) throughout country have been mandated to translate state-of-the-art research communities and enhance clinical care for patients within their catchment areas, including minority underrepresented populations. Precision oncology, which leverages genetics optimize personalized treatment plans patients, has promising potential address health disparities. In this era of targeted...