- COVID-19 epidemiological studies
- Influenza Virus Research Studies
- COVID-19 and Mental Health
- Viral Infections and Outbreaks Research
- Resilience and Mental Health
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Agricultural risk and resilience
- Hepatitis C virus research
- Yersinia bacterium, plague, ectoparasites research
- Health disparities and outcomes
- COVID-19 Pandemic Impacts
- Dental Research and COVID-19
- Healthcare professionals’ stress and burnout
- Fungal Biology and Applications
- Food Safety and Hygiene
- Microbial Metabolism and Applications
- Viral Infections and Vectors
- Bacterial biofilms and quorum sensing
- Hepatitis B Virus Studies
- demographic modeling and climate adaptation
- Immune Cell Function and Interaction
- Glaucoma and retinal disorders
- Ophthalmology and Eye Disorders
- SARS-CoV-2 detection and testing
University of Nottingham
1996-2024
Portsmouth Hospitals NHS Trust
2023
The University of Melbourne
2012-2014
Melbourne Health
2012
Kent County Council
1996
We aimed to explore university students’ perceptions and experiences of SARS-CoV-2 mass asymptomatic testing, social distancing self-isolation, during the COVID-19 pandemic. This qualitative study comprised four rapid online focus groups conducted at a higher education institution in England, high alert (tier 2) national restrictions. Participants were purposively sampled students (n = 25) representing range gender, age, living circumstances (on/off campus), testing/self-isolation...
We aimed to explore university students’ perceptions and experiences of SARS-CoV-2 mass asymptomatic testing, social distancing self-isolation during the COVID-19 pandemic. This qualitative study comprised four rapid online focus groups conducted at a higher education institution in England high alert (tier 2) national restrictions. Data were analysed thematically. Participants purposively sampled students (n = 25) representing range gender, age, living circumstances (on/off...
In this paper, we present work on SARS-CoV-2 transmission in UK higher education settings using multiple approaches to assess the extent of university outbreaks, how much those outbreaks may have led spillover community, and expected effects control measures. Firstly, found that distribution universities late 2020 was consistent with importation infection from arriving students. Considering at one university, larger halls residence posed risks for transmission. The dynamics wider communities...
Strains of Staphylococcus aureus which colonize defeathering machinery and become endemic within poultry processing plants appear to be resistant the normal cleaning disinfection processes. The resistance strains chlorine was compared with that isolates from natural skin flora poultry. Endemic were almost eight times more this due primarily their ability grow in macroclumps but also production an extracellular slime layer.
To assess the likely benefit of interventions under consideration for use in Mongolia during future influenza pandemics.A stochastic, compartmental patch model susceptibility, exposure, infection and recovery was constructed to capture key effects several interventions--travel restrictions, school closure, generalized social distancing, quarantining close contacts, treatment cases with antivirals prophylaxis contacts--on dynamics epidemics. The optimal timing duration each these were...
Psychological factors can influence susceptibility to viral infections. We examined whether such influences are evident in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.Participants (n = 102) completed measures of anxiety, depression, positive mood, and loneliness provided a blood sample for the measurement antibodies SARS-CoV-2 spike nucleocapsid proteins.SARS-CoV-2 was significantly negatively associated with anxiety depression. The model remained significant after...
Background Realistic models of disease transmission incorporating complex population heterogeneities require input from quantitative mixing studies. We use contact diaries to assess the relative importance social settings in respiratory pathogen spread using three measures person hours (PCH) as proxies for risk with an aim inform bipartite network transmission. Methods and Findings Our survey examines behaviour a convenience sample 65 adults, each encounter classified occurring work, retail,...
Development and rollout of vaccines offers the best opportunity for population protection against SARS-CoV-2 (COVID-19) virus. However, hesitancy towards might impede successful uptake in United Kingdom, particularly young adults who demonstrate highest rates hesitancy. This prospective study explored COVID-19 vaccine whether reasons behind these attitudes changed during initial stages Kingdom's rollout.Data on vaccination intention were collected from a British university student cohort at...
Aim: We use the Remote Assessment of Disease and Relapses platform (RADAR) to collect Bluetooth contact location data from university students. test ability this technology objectively capture social interaction, explore propensity students respond changing COVID-19 regulations, investigate association between mood.
The sociological and biological factors which gave rise to the three pandemic waves of Spanish influenza in England during 1918-19 are still poorly understood. Symptom reporting data available for a limited set locations indicates that reinfection multiple occurred, suggesting role loss infection-acquired immunity. Here we explore changes host immunity, driven by combination within-host viral evolution, may play explaining weekly mortality wave-by-wave symptomatic attack-rates subset English...
Vaccines that trigger an influenza-specific cytotoxic T cell (CTL) response may aid pandemic control by limiting the transmission of novel influenza A viruses (IAV). We consider interventions with hypothetical CTL-inducing vaccines in a range epidemiologically plausible scenarios. estimate achievable reduction attack rate, and, adopting model linking epidemic progression to emergence IAV variants, opportunity for antigenic drift. demonstrate have limited utility modifying population-level...
We survey 62 users of a university asymptomatic SARS-CoV-2 testing service on details their activities, protective behaviours and contacts in the 7 days prior to receiving positive or negative PCR test result period October 2020–March 2021. The resulting data set is novel capturing very detailed social contact history linked disease status during significant restriction activities. use this explore 3 questions: (i) Did participation activities enhance infection risk? (ii) How do definitions...
Abstract Objective This study examined the COVID-19 risk perceptions and mental health of university students on returning to campus in midst pandemic. Methods An online survey was completed during first four weeks academic year (October 2020) by 897 students. The included demographics measures experiences testing, self-isolation, shielding, perceived risk, indices capturing related psychological responses Results We observed higher levels depression anxiety, but not stress, compared with...
During the SARS-CoV-2 pandemic, epidemic models have been central to policy-making. Public health responses shaped by model-based projections and inferences, especially related impact of various non-pharmaceutical interventions. Accompanying this has increased scrutiny over model performance, assumptions, way that uncertainty is incorporated presented. Here we consider a population-level model, focusing on how distributions representing host infectiousness infection-to-death times are...
This paper is part of a special issue on Behavioural Epidemiology.
About 1% of Staphylococcus aureus cells survived the production gelatin sheets containing nutrient broth. Those which showed no evidence injury. Growth occurred in rubbery state with a w values 0.98 and 0.93; viability decreased during storage at 0.89, 0.62 0.36 but there was little loss an 0.25 over 27 d 26°C. Assays for enterotoxin A detected synthesis new toxin pre‐formed toxin. The results suggest that high levels Staph. its toxins should be excluded from glassy food products order to...
Abstract Background The impact of changing social restrictions on the mental health students during COVID-19 pandemic warrants exploration. Aims To prospectively examine changes to university students’ pandemic. Methods Students completed repeated online surveys at three time points (October 2020 (baseline), February 2021, March 2021) explore relationships between demographic and psychological factors (loneliness positive mood) outcomes (depression, anxiety, stress). Results A total 893...
A 5-year-old boy (sibling one) and his 11-year-old sister two) were presented to the hospital eye service in early 2021, having both developed acute-onset large angle esotropia within three months of each other. Neither had any significant past medical, ophthalmic, or family history. The siblings lived same household, experienced lifestyle changes as a result UK lockdown response COVID-19.Sibling one moderate right esotropia, initially maintained straight by corneal light reflex. He measured...