A5065236239- Microbial Natural Products and Biosynthesis
- Microbial Metabolic Engineering and Bioproduction
- Metabolomics and Mass Spectrometry Studies
- Gut microbiota and health
- Health, Environment, Cognitive Aging
- Radiomics and Machine Learning in Medical Imaging
- Enzyme Catalysis and Immobilization
- Viral Infectious Diseases and Gene Expression in Insects
- Bioinformatics and Genomic Networks
- Gene Regulatory Network Analysis
- Nutritional Studies and Diet
- Biomedical Text Mining and Ontologies
Centre international de recherche sur le cancer
2022-2023
University of Manchester
2018-2020
Metabolites produced by the gut microbiota play an important role in cross-talk with human host. Many microbial metabolites are biologically active and can pass barrier make it into systemic circulation, where they form exposome, i.e. totality of body fluids or tissues A major difficulty faced when studying exposome its health diseases is to differentiate solely partially derived from metabolism those host coming diet. Our objective was collect data scientific literature build a database on...
Streptomyces species produce a vast diversity of secondary metabolites clinical and biotechnological importance, in particular antibiotics. Recent developments metabolic engineering, synthetic systems biology have opened new opportunities to exploit metabolism, but achieving industry-level production without time-consuming optimization has remained challenging. Genome-scale modelling been shown be powerful tool guide engineering strategies for accelerated strain optimization, several...
Summary The issue of standardization in synthetic biology is a recurring one. As discipline that incorporates engineering principles into biological designs, needs effective ways to communicate results and allow different researchers (both academic industrial) build upon previous improve on existing designs. An aspect left out the discussions, especially when they happen at level industrial consortia or policymaking, whether not standards are applicable even useful everyday research...
Abstract Our goal was to study the spatial complexity of HPV negative OC by integrating scRNAseq and transcriptomics from 11 samples including 5 never smokers drinkers (NSND). We used Turing Biosystems proprietary graph database engine automated reasoning AI analyze model cell-cell biochemical cellular interactions in TME. The tumors H&E images, Visium 10X, single cell 10X data were pre-processed using standard methods. QC-based genes cells filtering, gene expression normalization,...
Abstract Background. Metabolites produced by the gut microbiota play an important role in cross-talk with human host. Many microbial metabolites are biologically active and can pass barrier make it into systemic circulation, where they form exposome, i.e. totality of body fluids or tissues A major difficulty faced when studying exposome its health diseases is to differentiate solely partially derived from metabolism those host coming diet. Objective. To collect data scientific literature...
Abstract Background. Metabolites produced by the gut microbiota play an important role in cross-talk with human host. Many microbial metabolites are biologically active and can pass barrier make it into systemic circulation, where they form exposome, i.e. totality of body fluids or tissues A major difficulty faced when studying exposome its health diseases is to differentiate solely partially derived from metabolism those host coming diet. Objective. To collect data scientific literature...