- Marine Invertebrate Physiology and Ecology
- Photoreceptor and optogenetics research
- Cephalopods and Marine Biology
- Marine and fisheries research
- Fish Ecology and Management Studies
- Neurobiology and Insect Physiology Research
- Cell Image Analysis Techniques
- Plant and Biological Electrophysiology Studies
- Image Processing Techniques and Applications
- Nicotinic Acetylcholine Receptors Study
- Nanofabrication and Lithography Techniques
- Nutritional Studies and Diet
- Marine Bivalve and Aquaculture Studies
- Advanced Fluorescence Microscopy Techniques
- Aquaculture Nutrition and Growth
- Aquatic Ecosystems and Phytoplankton Dynamics
- Neuroendocrine regulation and behavior
- Chemical synthesis and alkaloids
- Isotope Analysis in Ecology
- Obesity, Physical Activity, Diet
- Dietetics, Nutrition, and Education
- Cholinesterase and Neurodegenerative Diseases
- Anatomy and Medical Technology
- Fish Biology and Ecology Studies
- Nutrition, Genetics, and Disease
MRC Laboratory of Molecular Biology
2021-2023
University College Dublin
2018-2021
Fast cholinergic neurotransmission is mediated by acetylcholine-gated ion channels; in particular, excitatory nicotinic acetylcholine receptors play well established roles virtually all nervous systems. Acetylcholine-gated inhibitory channels have also been identified some invertebrate phyla, yet their the system are less understood. We report existence of multiple new with diverse ligand activation properties
Few animal groups can claim the level of wonder that cephalopods instill in minds researchers and general public. Much cephalopod biology, however, remains unexplored: largest invertebrate brain, difficult husbandry conditions, complex (meta-)genomes, among many other things, have hindered progress addressing key questions. However, recent technological advancements sequencing, imaging, genetic manipulation opened new avenues for exploring biology these extraordinary animals. The molecular...
Coleoid cephalopods such as the common octopus have a complex visual system, with camera-type eye and large optic lobe, that evolved independently from its counterpart in vertebrates. However, molecular neurochemical basis of signalling Octopus circuits is not well understood. Through heterologous expression ligand-gated ion channel genes vulgaris, we identified characterised novel ionotropic receptors for two major lobe neurotransmitters, dopamine acetylcholine. One these, DopC1, defines...
With technologies rapidly evolving, many research institutions are now opting to invest in costly, high-quality, specialized microscopes which shared by researchers. As a consequence, the user may not have ability adapt microscope their specific needs and limitations experimental design introduced. A flexible work-horse microscopy system is valuable tool any laboratory meet diverse of team promote innovation design. We developed Flexiscope; multi-functional, adaptable, efficient...
Creel surveys were performed over a three week period in late spring, 2011, the Lafourche and Calcasieu area estuaries of Louisiana Gulf Coast.Weights lengths measured for black drum (Pogonias cromis), red (Sciaenops ocellatus), spotted seatrout (Cynoscion nebulosus), relative condition factors calculated to expected weights from long term (5 year) data each species.A normal factor is 1.00.The mean drum, 0.955 ± 0.020; 0.011; seatrout, 0.994 0.009.In area, 0.934 0.017; 0.965 0.014; 0.971...
Abstract Neurobiological research focuses on a small number of model organisms, broadening the pool animals used in may lead to important insights into evolution nervous systems. The ctenophore is emerging as promising model, but we are currently lacking an understanding relationship between behaviour and environment which part due lack standardised long-term laboratory husbandry system. We established collection system for wild caught Pleurobrachia pileus . examined behavioural profile over...
An abstract is not available for this content. As you have access to content, full HTML content provided on page. A PDF of also in through the 'Save PDF' action button.
Neuroscience lacks a diverse repertoire of model organisms, resulting in an incomplete understanding the general principles neural function. Ctenophores display many neurobiological and experimental features which make them promising candidate to fill this gap. They possess nerve net distributed across their body surface epithelial layer. There is long-held assumption that nets are "simple" lack distinct organizational principles. We want challenge determine how stereotyped structure network...
Abstract With technologies rapidly evolving, many research institutions are now opting to invest in costly, high-quality, specialised microscopes which shared by researchers. As a consequence, the user may not have ability adapt microscope their specific needs and limitations experimental design introduced. A flexible work-horse microscopy system is valuable tool any laboratory meet diverse of team promote innovation design. We developed Flexiscope; multi-functional, adaptable, efficient...
Much has been written about introduced rainbow trout interbreeding and outcompeting native cutthroat trout. However, specific mechanisms have not thoroughly explored, most data is limited to lotic ecosystems. Samples of Snake River (Oncorhynchus clarkii bouvieri), the rainbow-cutthroat hybrid, cutbow (Onchorhynchus mykiss x clarkii), mykiss), were obtained from a lentic ecosystem (Eleven Mile Reservoir, Colorado) by creel surveys conducted May October, 2012. The total length weight each fish...
Abstract Fast cholinergic neurotransmission is mediated by acetylcholine-gated ion channels; in particular, excitatory nicotinic acetylcholine receptors play well established roles virtually all nervous systems. Acetylcholine-gated inhibitory channels have also been identified some invertebrate phyla, yet their the system are less understood. We report existence of multiple new with diverse ligand binding properties C. elegans . identify three channels, LGC-40, LGC-57 and LGC-58, whose...
Quantifying interaction strength between species is of interest in food web studies for understanding population dynamics. Theory has run ahead experiment solving equations describing ecological systems (the Lotka-Volterra equations, example). Modeling approaches depend upon quantitative knowledge strengths among species, yet there are few methods available estimating interactions especially the field. Competition and predation fishes traditionally studied with a variety methods, most...
A large, annually recurring region of hypoxia in the northern Gulf Mexico has been attributed to water stratification and nutrient loading nitrogen phosphorus delivered by Mississippi Atchafalaya rivers. This increased nearly 300% since 1950, primarily due use agricultural fertilizers. Over this same time period, red snapper (Lutjanus campechanus) population shifted strongly from being dominated eastern western Mexico, with bulk current regions significant rivers or near areas development...
An abstract is not available for this content. As you have access to content, full HTML content provided on page. A PDF of also in through the ‘Save PDF’ action button.
Abstract Neuroscience currently lacks a diverse repertoire of model organisms, resulting in an incomplete understanding what principles neural function generalise and are species-specific. Ctenophores display many neurobiological experimental features which make them promising candidate to fill this gap. They possess nerve net distributed across their outer body surface, just beneath the epithelial layer. There is long-held assumption that nets ‘simple’ random while lacking distinct...