A5103245705- Inhalation and Respiratory Drug Delivery
- Aerosol Filtration and Electrostatic Precipitation
- Particle Dynamics in Fluid Flows
- Infection Control and Ventilation
- Air Quality and Health Impacts
- Light effects on plants
- Spaceflight effects on biology
- Transportation Safety and Impact Analysis
- Automotive and Human Injury Biomechanics
- Cystic Fibrosis Research Advances
- Cellular and Composite Structures
- Advanced Thermodynamics and Statistical Mechanics
- Occupational and environmental lung diseases
- Cyclone Separators and Fluid Dynamics
- Tracheal and airway disorders
- Advanced Thermodynamic Systems and Engines
- Heme Oxygenase-1 and Carbon Monoxide
Huazhong University of Science and Technology
2020-2024
Although pulmonary drug delivery has been deeply investigated, the effect of laryngeal jet on particle deposition during with dry powder inhalers (DPI) not evaluated profoundly. In this study, flow structure and pattern a DPI in two airway models, one mouth-throat region including larynx other without it, are numerically investigated. The results revealed that considerable deposition. presence leads to 4-fold 2-fold higher efficiencies for inlet rates 30 90 L/min, respectively.
Airway stenosis is a global respiratory health problem that caused by airway injury, endotracheal intubation, malignant tumor, lung aging, or autoimmune diseases. A precise understanding of the airflow dynamics and pharmaceutical aerosol transport through multi-stenosis airways vital for targeted drug delivery, missing from literature. The object this study primarily relates to behaviors nanoparticle sections trachea upper airways. combination CT-based mouth–throat model Weibel’s was adopted...