Jingyu Chen

ORCID: 0000-0003-0497-7591
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About
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Research Areas
  • Monoclonal and Polyclonal Antibodies Research
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • Estrogen and related hormone effects
  • Cytokine Signaling Pathways and Interactions
  • Receptor Mechanisms and Signaling
  • Inflammatory mediators and NSAID effects
  • Rheumatoid Arthritis Research and Therapies
  • Blockchain Technology Applications and Security
  • Chronic Lymphocytic Leukemia Research
  • Auction Theory and Applications
  • Higher Education and Teaching Methods
  • Immune Cell Function and Interaction
  • Parasites and Host Interactions
  • Educational Technology and Pedagogy
  • Privacy-Preserving Technologies in Data
  • Genomic variations and chromosomal abnormalities
  • Systemic Lupus Erythematosus Research
  • Cloud Computing and Resource Management
  • Research on Leishmaniasis Studies
  • Immune cells in cancer
  • Cancer Immunotherapy and Biomarkers
  • Psoriasis: Treatment and Pathogenesis
  • Immune Response and Inflammation
  • Organ Transplantation Techniques and Outcomes

Anhui Medical University
2013-2023

Zhejiang Shuren University
2023

Army Medical University
2019

Southwest Hospital
2019

Ministry of Education of the People's Republic of China
2013-2016

Hangzhou Dianzi University
2014-2015

Chongqing Medical University
2012

Second Affiliated Hospital of Chongqing Medical University
2012

Dalian Medical University
2012

Abstract Rheumatoid arthritis (RA) is characterized by inflammation of the synovium, which leads to progressive destruction cartilage and bone. Adrenoreceptor (AR) signaling may play an important role in modulating dendritic cell (DC), be involved pathogenesis RA. We examined effect β-AR agonist isoprenaline (ISO) on DC function, impact β 2 -AR salbutamol adjuvant-induced arthritic (AA) rats changes DCs during course AA. ISO inhibited expression surface molecules CD86 MHC-II, stimulation T...

10.1038/srep24548 article EN cc-by Scientific Reports 2016-04-15

Dendritic cells (DCs) are the most powerful antigen-presenting that have an important role in immunity and immune tolerance. Transforming growth factor β (TGF-β) is a pleiotropic cytokine widely expressing various tissues cells, which regulates cellular proliferation, differentiation apoptosis of several considered to be key inducing The effect TGF-β on DCs very complex. In this study, we further investigated tolerance DCs. were differentiated from mice bone marrow absence or presence TGF-β....

10.3109/08820139.2013.879172 article EN Immunological Investigations 2014-01-31

T helper type 17 (Th17) cell which is induced by interleukine-6 (IL-6)-signal transducers and activators of transcription 3 (STAT3) signaling a central pro-inflammatory subtype in rheumatoid arthritis (RA) could be significantly reduced paeoniflorin-6'-O-benzene sulfonate (CP-25) treatment with unclear mechanisms. This study was aimed to found out the mechanism CP-25 hampering Th17 cells differentiation arthritic animals thus explore more therapeutic targets for RA. In mice collagen-induced...

10.1016/j.biopha.2022.113997 article EN Biomedicine & Pharmacotherapy 2022-11-15

For the random arrival tasks, maximum of social welfare by allocating VMs in private cloud is concerned this work. The model allocation online mechanism built, which single-valued, non-parallel, and preemptive. A preemptive proposed, truthfulness proved, competitive ratio given a simple situation. Many simulations are implemented using real tasks from data center with value exponential distribution, indicate good actual ratio. Some results revealed comparison offline optimum different C, λ,...

10.1109/dcit.2015.27 article EN 2015-11-01

Objective To study the influence of preoperative splenectomy on liver transplantation for portal hypertension and management complications.Methods From January 2008 to 2013,a total 136 patients underwent (PHT) in Hepatobiliary Surgery Center,Fuzhou General Hospital PLA Nanjing Military Region.Pre-liver was carried out 19 patients.We randomly selected according operation time 50 cases as control group.The time,bleeding,blood transfusion,infection,the incidence acute rejection,biliary...

10.3760/cma.j.issn.1007-8118.2014.08.006 article EN Zhonghua gan-dan waike zazhi 2014-08-28
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