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Damian Harris

ORCID: 0000-0003-0512-0100
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About
Contact & Profiles
A5004596031
Research Areas
  • Advancements in Battery Materials
  • Advanced Proteomics Techniques and Applications
  • Supercapacitor Materials and Fabrication
  • Advanced Battery Technologies Research
  • Mass Spectrometry Techniques and Applications
  • Biosensors and Analytical Detection
 Engineered nanoparticles enable deep proteomics studies at scale by leveraging tunable nano–bio interactions
OPENALEX - Publications 
Shadi Ferdosi Behzad Tangeysh Tristan R. Brown Patrick A. Everley Michael Figa and 26 more Matthew McLean Eltaher M. Elgierari Xiaoyan Zhao Veder J. Garcia Tianyu Wang Matthew E.K. Chang Kateryna Riedesel Jessica Chu Max Mahoney Hongwei Xia Evan S. O’Brien Craig Stolarczyk Damian Harris Theodore L. Platt Philip Ma Martin Goldberg Róbert Langer Mark R. Flory Ryan W. Benz Wei Tao Juan C. Cuevas Serafim Batzoglou John E. Blume Asim Siddiqui Daniel Hornburg Omid C. Farokhzad

SignificanceDeep profiling of the plasma proteome at scale has been a challenge for traditional approaches. We achieve superior performance across dimensions precision, depth, and throughput using panel surface-functionalized superparamagnetic nanoparticles in comparison to conventional workflows deep proteomics interrogation. Our automated workflow leverages competitive nanoparticle-protein binding equilibria that quantitatively compress large dynamic range proteomes an accessible scale....

10.1073/pnas.2106053119 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2022-03-11
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