A5048696566- Nanoplatforms for cancer theranostics
- Advanced Drug Delivery Systems
- Nanoparticle-Based Drug Delivery
- Nanoparticles: synthesis and applications
- Electrochemical sensors and biosensors
- Phase Equilibria and Thermodynamics
- Graphene and Nanomaterials Applications
- Cancer Cells and Metastasis
- Advanced Photocatalysis Techniques
- Pancreatic and Hepatic Oncology Research
- Cancer Immunotherapy and Biomarkers
- Ga2O3 and related materials
- Cancer, Hypoxia, and Metabolism
- Bacterial Identification and Susceptibility Testing
- Analytical Chemistry and Chromatography
- Phagocytosis and Immune Regulation
- Immunotherapy and Immune Responses
- Pesticide Residue Analysis and Safety
- Analytical chemistry methods development
- Computational Drug Discovery Methods
- Analytical Chemistry and Sensors
- Advancements in Transdermal Drug Delivery
- Antimicrobial Resistance in Staphylococcus
- Hydrogels: synthesis, properties, applications
- Hepatitis C virus research
Taif University
2017-2025
National Guard Health Affairs
2022
King Abdulaziz University
2022
King Saud bin Abdulaziz University for Health Sciences
2022
King Abdullah International Medical Research Center
2022
Wayne State University
2017-2021
Eugene Applebaum College of Pharmacy and Health Sciences
2017-2021
University of Toledo
2015-2018
This work includes green synthesis of magnesium oxide nanoparticles (MgO NPs) by using Alstonia scholaris , which is indigenous to many countries such as China, Australia, Sri Lanka, Pakistan, and India. Its pharmacological activities include antidiabetic, antioxidant, anticancer, analgesic, antitussive, anti-diarrheal activities. In this study, the antioxidant anti-inflammatory bio-inspired nanoparticles, MgO NPs, were investigated. NPs prepared leaf extract scholaris, followed...
Wounds are the most common causes of mortality all over world. Topical drug delivery systems more efficient in treating wounds as compared to oral because they bypass disadvantages route. The aim present study was formulate and evaluate vitro vivo nanoemulgels loaded with eucalyptol for wound healing. Nanoemulsions were prepared using solvent emulsification diffusion method by mixing an aqueous phase oil phase, a nanoemulgel then fabricated nanoemulsions gelling agent (Carbopol 940) 1:1...
The purpose of this study was to assess the parameters doxorubicin (DOX) loaded lipid polymer hybrid nanoparticles (LPHNs) formulation development, and then bioavailability DOX were determined in rabbit model, order evaluate intrinsic outcome dosage form improvement after oral administration. LPHNs prepared by combine approach, using both magnetic stirring probe sonication followed its characterization terms size-distribution (Zeta Size), entrapment efficiency (EE), loading capacity,...
The aim of this study was to develop a novel folate receptor-targeted drug delivery system for retinoblastoma cells using promising anticancer agent, curcumin-difluorinated (CDF), loaded in polymeric micelles. Folic acid used as targeting moiety enhance the and bioavailability CDF. For purpose, amphiphilic poly(styrene-co-maleic acid)-conjugated-folic (SMA-FA) synthesized utilized improve aqueous solubility highly hydrophobic, but very potent compound, CDF, its targeted overexpressing...
Identified as the second leading cause of cancer-related deaths among American women after lung cancer, breast cancer all types has been focus numerous research studies. Even though triple-negative (TNBC) represents 15–20% number cases worldwide, its existing therapeutic options are fairly limited. Due to pivotal role presence/absence specific receptors luminal A, B, HER-2+, and TNBC in molecular classification lack these accounted for aforementioned limitation. Thereupon, an attempt...
ABSTRACT The environmental impact of chemicals used in aquaculture, particularly nitrofurantoin, has raised global concern. Nitrofurantoin, a broad‐spectrum antimicrobial, is commonly aquaculture despite safety risks. Determination nitrofurantoin water samples fish ponds necessary to ensure the and quality seafood. Herein, new spectrofluorometric method was created for determination from ponds. Carbon quantum dots were functionalized with tetra phenyl borate modifying their surface be...
In the present study, a simple, rapid and cost-effective analytical method was developed for simultaneous determination of three commonly prescribed cardiovascular drugs: propranolol, rosuvastatin valsartan. The employed artificial neural networks (ANN) to model relation between UV absorption spectra drugs their concentrations. An experimental design 25 samples as calibration set, central composite 20 used validation set. firefly algorithm (FA) evaluated variable selection procedure optimize...
Abstract Hypertension and hyperlipidemia are two common conditions that require effective management to reduce the risk of cardiovascular diseases. Among medications commonly used for treatment these conditions, valsartan pitavastatin have shown significant efficacy in lowering blood pressure cholesterol levels, respectively. In this study, synchronous spectrofluorimetry coupled chemometric analysis tools, specifically concentration residual augmented classical least squares (CRACLS)...
A sensitive “turn-off” fluorescent method using MPA-CdTe quantum dots was developed for the selective determination of lurasidone in pharmaceutical formulations, spiked plasma, and environmental water samples.