A5068106305- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Empathy and Medical Education
- Innovations in Medical Education
- Ethics in medical practice
- Pain Management and Placebo Effect
- Nutrition, Genetics, and Disease
- Mental Health and Psychiatry
- Healthcare cost, quality, practices
- Vasculitis and related conditions
- Autoimmune and Inflammatory Disorders Research
- Medical Malpractice and Liability Issues
- Infectious Diseases and Tuberculosis
- Inflammatory mediators and NSAID effects
- Global Health Workforce Issues
- Spondyloarthritis Studies and Treatments
- Nursing education and management
- Ethics in Clinical Research
- Interprofessional Education and Collaboration
- Peripheral Neuropathies and Disorders
- Clinical Reasoning and Diagnostic Skills
- Complementary and Alternative Medicine Studies
- Drug-Induced Adverse Reactions
- Otitis Media and Relapsing Polychondritis
- Musculoskeletal Disorders and Rehabilitation
Liverpool John Moores University
2023-2024
The University of Sydney
2014-2023
Dubbo Hospital
2016-2023
Western NSW Local Health District
2023
Royal North Shore Hospital
1988-2014
Northern Sydney Local Health District
2013-2014
Arthritis Australia
2013
King's College London
2012
Guy's Hospital
1993
Poliklinik für Zahnärztliche Prothetik
1991
Objective To evaluate barriers that prevent rheumatoid arthritis (RA) patients from achieving Disease Activity Score in 28 joints using the erythrocyte sedimentation rate (DAS28‐ESR) scores within current recommended levels for low disease activity (LDA) or clinical remission (DAS28‐ESR score <3.2). Methods Using an electronic medical record program, data RA treated Optimising Patient Outcomes Australian Rheumatology clinics, with a recorded DAS28‐ESR score, were collected at one point...
1. Enteric coated sodium salicylate 4.8 g daily was compared with the same dose of enteric aspirin in 18 patients rheumatoid arthritis. 2. After an initial washout period lasting 3 days, were randomly allocated to treatment or aspirin. 2 weeks two treatments crossed over. 3. Pain relief, reduction articular index joint tenderness, increase grip strength, decrease digital circumference and patients' assessment showed significant improvement both period. No differences found between therapies....
Objective. To assess the safety of treating patients with rheumatoid arthritis a combination methotrexate (MTX) and leflunomide (LEF) in comparison to MTX monotherapy, clinical practice. Methods. The Safety Methotrexate Combination Leflunomide Rheumatoid Arthritis (SMILE) study was multicenter, observational, cross-sectional, retrospective study. conducted by Optimising Patient Outcomes Australian Rheumatology-Quality Use Medicines Initiative (OPAL QUMI). Data were deidentified for patient,...
Five cases (three children and two young women) of sterile inflammatory arthritis are described, each preceded by a streptococcal infection. A throat swab from one patient grew group A, beta haemolytic streptococci, in case unequivocal evidence seroreaction to antigens was present. The long term outcome all excellent, though (female, 24 years age) required prophylactic penicillin for three months. diagnosis definite recent infection is sometimes difficult as swabs may be negative the...
Importance There is a need for observational studies to supplement evidence from clinical trials, and the target trial emulation (TTE) framework can help avoid biases that be introduced when treatments are compared crudely using data by applying design principles randomized trials. Adalimumab (ADA) tofacitinib (TOF) were shown equivalent in patients with rheumatoid arthritis (RA) trial, but our knowledge, these drugs have not been head-to-head routinely collected TTE framework. Objective To...
Fifty-three patients with rheumatoid arthritis who required immunosuppressive therapy were commenced in a randomized trial comparing azathioprine to weekly oral pulse methotrexate. After an initial 24-week period, both groups had significantly improved from baseline measures of pain and functional capacity there no significant differences clinical outcomes between the two groups. Laboratory variables disease activity showed improvement haemoglobin ESR methotrexate group. Subsequently,...
Objectives To evaluate the disease activity and current pharmacological interventions used to achieve remission in rheumatoid arthritis (RA) patients Australia. Methods Rheumatoid treated participating Australian clinics were included study. Patient demographics, onset, medications measures analyzed. Data, de-identified patient, clinic clinician captured using an electronic clinical management program. The score (DAS28) was classify into states of remission, low (LDA), moderate (MDA) high...
The EVOLVE (evaluating evidence, enhancing efficiencies) initiative aims to drive safer, higher-quality patient care through identifying and reducing low-value practices.To determine the Australian Rheumatology Association's (ARA) 'top five' list of practices.A working group comprising 19 rheumatologists three trainees compiled a preliminary list. Items were retained if there was strong evidence low value high or increasing clinical use and/or cost. All ARA members (356 72 trainees) invited...
Abstract: A 72‐year‐old female with a recent episode of podagra, without peripheral tophi, presented nocturnal back pain and destructive lesion the right lamina L4. tophus was excised at laminectomy. Evidence an axial skeletal causing irritative radiculopathy via mass effect is presented.
Mycobacterium terrae is ubiquitous in our environment. M infections most commonly involve tendon sheaths, bones, bursae, and joints. We report a case of infectious arthritis the knee caused by 21-year-old man who had non-specific chronic synovitis. No organism was seen on microscopy or isolated from cultures until months later. Initially culture considered contaminant specific anti-mycobacterial treatment not advised. The patient commenced suppressive therapy for persistent effusion...
1. A clinical trial was conducted with flurbiprofen 100 mg three times a day by mouth in rheumatoid arthritis to determine variability response. 2. Forty patients entered the study, but only 32 completed it. Patients were treated on two occasions at month's interval, each being preceded 3 wash out period. Pain relief and Ritchie articular index of joint tenderness assessed beginning end treatment 3. Flurbiprofen produced significant improvement both pain tenderness. No differences observed...
SummaryA randomized study was performed on 24 patients with ankylosing spondylitis to compare the efficacy and tolerability of 20 mg tenoxicam daily 50 diclofenac twice daily. There were 6 withdrawals from group taking 4 group. Depression in 1 patient only significant adverse event. Both drugs otherwise well tolerated. Tenoxicam rated as good or excellent by 27% 5.5% patients, respectively. Global assessment, pain duration morning stiffness improved both but this improvement not...
This paper explores the counterfactual aspects of Person-Centred Healthcare (PCH). PCH as promoted appears to have self-evident value an expression humanism in medical care, but this can be deceptive. Despite its rhetorical appeal, there is limited evidence that it improves either experience or outcomes healthcare. More problematically, commonly overlooked philosophical assumptions upon which rests carry with them other, more malign ideologies and healthcare movements such preference-driven...
Gout is one of the most common inflammatory arthropathies, and pathogenesis well understood. In Australia, patients with chronic tophaceous gout (CTG) are treated by general practitioners (GPs). Urate-lowering therapy, if adhered to continuously, can suppress disease, reduce likelihood flares prevent long-term complications such as disfiguring tophi joint damage. Many rheumatology societies recommend a treat-to-target (T2T) approach, lowering serum urate 0.35 mmol/L or below therapy.The aim...
The COVID-19 pandemic has, of necessity, demanded the rapid incorporation virtual technologies which, suddenly, have superseded physical medical encounter. These imperatives been implemented in advance evaluation, with unclear risks to patient care and nature practice that might be justifiable context a but cannot extrapolated as new standard care. Models fit for purpose should not generalized reconfigure by default, personal exception at conclusion emergency.