- Mycobacterium research and diagnosis
- Microbial infections and disease research
- Viral gastroenteritis research and epidemiology
- Brucella: diagnosis, epidemiology, treatment
- Bacteriophages and microbial interactions
- Animal Virus Infections Studies
- Antibiotic Resistance in Bacteria
- Escherichia coli research studies
- Salmonella and Campylobacter epidemiology
- Ginseng Biological Effects and Applications
- Galectins and Cancer Biology
- Viral Infections and Vectors
- Animal Disease Management and Epidemiology
- Vector-Borne Animal Diseases
- Tuberculosis Research and Epidemiology
- Pharmacological Effects of Natural Compounds
- Bacterial biofilms and quorum sensing
- Aquaculture disease management and microbiota
- Veterinary medicine and infectious diseases
- Monoclonal and Polyclonal Antibodies Research
- Immune Response and Inflammation
- Virus-based gene therapy research
- Probiotics and Fermented Foods
- Antimicrobial Resistance in Staphylococcus
- Rabies epidemiology and control
Seoul National University
2016-2025
John Wiley & Sons (United States)
2020
Hudson Institute
2020
Seoul National University of Science and Technology
2014-2017
Gyeongsang National University
2016
Konkuk University
2015
Inha University
2014
Animal and Plant Quarantine Agency
2013
Jeonbuk National University
2012
New Generation University College
2011
Clostridium perfringens has been classified into five toxigenic types (A through E) on the basis of its capability to produce major lethal toxins (alpha, beta, epsilon, and iota toxins). Seroneutralization with mice or guinea pigs used type each toxin, but this conventional method some disadvantages. Therefore, we a molecular biological technique bacterium in present study. A multiplex PCR was developed for purpose. This several advantages comparison seroneutralization pigs. By method, also...
The current study focused on an environment friendly method for degradation of Low Density Polyethylene (LDPE) using bacteria. A total 36 bacterial strains were isolated from waste disposal sites in which six showed potential biodegradation activities. In this study, we reported 2 new i.e. Bacillus siamensis and wiedmannii LDPE degradation. percent weight loss films isolates was; B. (8.46 ± 0.3%), cereus (6.33 0.2%), (5.39 subtilis (3.75 0.1%), P. aeruginosa (1.15 0.1%) A. iwoffii (0.76...
In this study, we determined the effects of hederagenin isolated from Akebia quinata fruit on alcohol-induced hepatotoxicity in rats. Specifically, investigated hepatoprotective, anti-inflammatory, and anti-apoptotic hederagenin, as well role AKT mitogen-activated protein kinase (MAPK) signaling pathways ethanol-induced liver injury. Experimental animals were randomly divided into three groups: normal (sham), 25% ethanol, ethanol + (50 mg/kg/day). Each group was orally administered...
ABSTRACT The aim of this study was to investigate the prevalence and transferability resistance in tetracycline-resistant Escherichia coli isolates recovered from beef cattle South Korea. A total 155 E. were collected feces Korea, 146 confirmed be resistant tetracycline. tetracycline gene tet (A) (46.5%) most prevalent, followed by (B) (45.1%) (C) (5.8%). Strains carrying plus detected two each. In terms phylogenetic grouping, 101 (65.2%) classified as group B1, decreasing order D (17.4%),...
A novel coronavirus emerged in human populations and spread rapidly to cause the global disease 2019 pandemic. Although origin of associated virus (severe acute respiratory syndrome 2 [SARS-CoV-2]) remains unclear, genetic evidence suggests that bats are a reservoir host virus, pangolins probable intermediate. SARS-CoV-2 has crossed species barrier infect humans other animal species, infected can facilitate reverse-zoonotic transmission animals. Considering changing interconnections among...
ABSTRACT The swine hepatitis E virus (HEV) is considered to be a new zoonotic agent due its close genomic resemblance the human HEV and ability infect nonhuman primates. Hepatitis caused by infection has been serious public health problem in developing countries. However, recent seroprevalence studies indicate that also circulates industrialized In this study, nested reverse transcription (RT)-PCR was developed detect part of open reading frame 2. Three Korean isolates were identified 128...
Protein kinase D (PKD) 1 influences cell migration by mediating both trans -Golgi vesicle fission and integrin recycling to the surface. Using restriction landmark genomic scanning methods, we found that promoter region of PKD1 was aberrantly methylated in gastric cancer lines. Silencing expression detected 72.7% lines examined, silencing associated with CpG hypermethylation . Treatment 5-aza-2′-deoxycytidine trichostatin A partially reversed methylation restored gene -silenced Real-time...
Salmonella (S.) Typhimurium and S. Enteritidis are the major causative agents of food-borne illnesses worldwide.Currently, a rapid detection system using multiplex real-time polymerase chain reaction (PCR) has been applied for other pathogens such as Escherichia coli, Staphylococcus aureus Streptococcus spp.A PCR was developed simultaneous spp., especially Enteritidis, in beef pork.For specific sensitive PCR, three representative primers probes were designed based on sequence data from...
Mesenchymal stem cells (MSCs) possess immunomodulatory activities, including suppression of T- and B-cell activation. However, their effects on atopic dermatitis (AD) have not yet been studied. Using an ovalbumin-induced AD mouse model, we investigated whether MSCs can be used as therapeutics in AD. We isolated both allogeneic syngeneic clonal (cMSCs) from bone marrow according to the subfractionation culturing method. Our cMSCs suppressed T-cell proliferation cytokine production, interferon...
Lumpy skin disease (LSD) is one of the most important emerging transboundary diseases. Recently, LSD has emerged in many countries northern hemisphere. The virus a huge genome and highly resistant to environmental conditions. also host-specific large ruminants, such as cattle domestic water buffalo, are particularly susceptible. In addition, wild ruminants can serve potential reservoirs for spreading virus. emergence might be related climate change various regions because an arthropod-borne...
Abstract Proteus mirabilis is a commensal bacterium dwelling in the gastrointestinal (GI) tract of humans and animals. Although New Delhi metallo-β-lactamase 1 (NDM-1) producing P. emerging as threat, its epidemiology our society remains largely unknown. LHPm1, first isolate harboring NDM-1, was detected from companion dog that resides with human owner. The whole-genome study revealed 20 different antimicrobial resistance (AMR) genes against various classes agents, which corresponded to MIC...
Background: Inflammatory stimuli can induce neutrophils to release nuclear DNA combined with histones into the extracellular space, forming neutrophil traps. Because inflammation contributes diabetic retinopathy, it is plausible that trap formation actively occurs in retinopathy. This case-control study investigated clinical relevance of circulating levels components as risk factors and further evaluated whether glucose induced vitro using whole blood from healthy volunteers. Methods:...
This article presents the results of selecting oligonucleotide primers and optimizing conditions for conducting a reverse transcription polymerase chain reaction (RT-PCR) to detect Newcastle disease virus genes. The choice target genes is based on fact that genome determines potential approaches using it as vector antigen delivery in development safe effective vaccines. offers several advantages: type species avian orthoavulavirus-1 (AOaV-1) group within Paramyxoviridae family, possesses an...