Rosângela da Silva Lopes

ORCID: 0000-0003-0549-0697
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About
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Research Areas
  • Bioactive Compounds and Antitumor Agents
  • Trypanosoma species research and implications
  • Synthesis and Biological Evaluation
  • Research on Leishmaniasis Studies
  • Insect Pest Control Strategies
  • Occupational Health and Safety in Workplaces
  • Tannin, Tannase and Anticancer Activities
  • Linguistics and Education Research
  • Skin Protection and Aging
  • Allelopathy and phytotoxic interactions
  • Insect and Pesticide Research
  • Geography and Environmental Studies
  • Synthesis and biological activity
  • Vector-borne infectious diseases
  • Catalysis for Biomass Conversion
  • Photodynamic Therapy Research Studies
  • Click Chemistry and Applications
  • Chemistry Education and Research
  • Ginkgo biloba and Cashew Applications
  • Phytochemistry and biological activity of medicinal plants
  • Phytochemistry Medicinal Plant Applications
  • Education Pedagogy and Practices
  • Multicomponent Synthesis of Heterocycles
  • Rural and Ethnic Education

Universidade Federal de Mato Grosso do Sul
2012-2024

Faculdade Evangélica do Paraná
2022

Instituto de Tecnología Química
2014

The control of tick species that affect animal production is vital for the economic welfare cattle industry. This study focused on testing acaricidal activity essential oil from leaves and stems Tagetes minuta against several Brazilian species, including Rhipicephalus (Boophilus) microplus, sanguineus, Amblyomma cajennense Argas miniatus. chemical composition was determined by chromatography spectroscopy analyses, which revealed presence monoterpenes. adult immersion test (AIT) larval packet...

10.1590/s1984-29612012000400011 article EN cc-by Revista Brasileira de Parasitologia Veterinária/Brazilian Journal of Veterinary Parasitology 2012-12-01

Octocrylene (2-ethylhexyl 2-cyano-3,3-diphenyl-2-propenoate) is present in several sunscreens and known to work synergistically with UV filters.We prepared eight octocrylene-related compounds test their photoprotective activities by measuring diffuse transmittance.The had varied photoprotection profiles, Sun Protection Factors (SPF) ranging from 1 5 UVA (UVAPF) 8. Compounds 4, 5, 7 showed the best protection against UVB sunrays, while 6, presented results for UVA, so compound most balanced...

10.5935/0100-4042.20140160 article EN cc-by-nc Química Nova 2014-01-01

Novel naphthoquinone derivatives were synthesized and tested for trypanocidal leishmanicidal activities. Compound <bold>11a</bold> was the most active against <italic>T. cruzi</italic>.

10.1039/c4ob01869a article EN Organic & Biomolecular Chemistry 2014-10-14

In pursuit of potential agents to treat Chagas disease and leishmaniasis, we report the design, synthesis, identification novel naphthoquinone hydrazide-based molecular hybrids. The compounds were subjected in vitro trypanocide leishmanicidal activities. N'-(1,4-Dioxo-1,4-dihydronaphthalen-2-yl)-3,5-dimethoxybenzohydrazide (13) showed best performance against Trypanosoma cruzi (IC50 1.83 µM) Leishmania amazonensis 9.65 µM). 4-Bromo-N'-(1,4-dioxo-1,4-dihydronaphthalen-2-yl)benzohydrazide (16)...

10.1590/0001-3765202420230375 article EN cc-by Anais da Academia Brasileira de Ciências 2024-01-01

Background: Fungi can play an important role in environmental remediation. A key class of pollutants is the aromatic amines (AA) comprising dyes, drugs, pesticides and products originated from combustion other industrial residues. The microbial N-acetylation known to be a chief detoxifying mechanism for noxious AA. However, this transformation not widely reported fungi. Keywords: Aromatic amines, Aspergillus japonicus, bioremediation, biotransformation, fungi detoxification, N-acetylation.

10.2174/1570178614666170221125955 article EN Letters in Organic Chemistry 2017-03-02

An efficient copper (I) halotriphenylphosphine catalyzed one-pot multicomponent reaction (MCR) of 3-substituted indole derivatives has been developed using a variety aldehydes (aromatic, aliphatic, and heteroaromatic), indole, active methylene substrates such as malononitrile ethyl 2-cyano acetate. This proceeds smoothly obtained good to excellent yields (68–93%) water green solvent under ambient conditions. The products were confirmed by 1H, 13C NMR, mass spectroscopy techniques. MCR occurs...

10.1080/00397911.2017.1394467 article EN Synthetic Communications 2017-12-14

Porphyrins are very attractive compounds due to their wide application in many areas of new materials as chemical technology, ecology, medicine and, electronics. In the last years, they also been a focus attention owing implications photocatalytic reactions. Cardanol (isolated form cashew nut shell liquid) and glycerol (side product biodiesel industry) raw low aggregated value; however, hold structures with functionalities that can lead products high commercial value Brazilian industry....

10.17807/orbital.v4i1.365 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2012-06-01

The naphthoquinones are cyclic aromatic α,β-dienonas with a basic framework derived from naphthalene. They also found in many higher plants, algae, fungi and as the product of  metabolism  of some  bacteria  having large biologica activity described literature such antibacterial, anti-inflammatory, antitumor, anticancer trypanocidal [1-3]. Castor oil is an abundant raw material Brazil great versatility and, it present biodiesel production, surfactants, cosmetics others. Considering...

10.17807/orbital.v4i1.362 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2012-06-01

A floresta amazônica é considerada a detentora da maior biodiversidade do mundo, em fauna e flora. Sua apresenta uma grande fonte de plantas ricas compostos bioativos, cuja exploração racional contribui para o desenvolvimento sustentável região. Na busca por extratos presente trabalho descreve os resultados dos testes fitoquímicos, toxicidade frente à Artemia salina, atividade larvicida extrato bruto etanólico serragem Astronium lecointei Ducke das folhas Cochlospernum orinocense (Kunth)...

10.34117/bjdv8n4-054 article PT Brazilian Journal of Development 2022-04-04

Este artigo é o resultado de pesquisa do tipo documental e bibliográfica em que se buscou conhecer analisar a Base Nacional Comum Curricular – BNCC, com fim identificar propostas educativas curriculares para pleno desenvolvimento sujeito ao longo da Educação Básica. Para tanto, mapeou os direitos à educação básica elencados na legislação brasileira. Dentre documentos, foram utilizados vários dispositivos legais, como exemplos: Constituição Federal Plano Educação. Utilizou-se também...

10.51891/rease.v8i7.6394 article PT cc-by Revista Ibero-Americana de Humanidades, Ciências e Educação 2022-07-30

Introduction: Chagas disease and Leishmaniasis are neglected diseases caused bythe Trypanosoma cruzi kentoplastid parasites Leishmania spp. Parasitic diseasescause great impact on social economic, affecting millions of people in the worldand represent a major global health problem. In search for new alternatives thetreatment disease, strategies have been used to discovernew active molecules, because there is an urgent need development newdrugs. this scenario, 1,4-naphthoquinones shown...

10.15446/rcciquifa.v51n2.98279 article EN Revista Colombiana de Ciencias Químico Farmacéuticas 2022-10-29
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