Michelle Saull

ORCID: 0000-0003-0558-0692
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About
Contact & Profiles
Research Areas
  • Sepsis Diagnosis and Treatment
  • COVID-19 Clinical Research Studies
  • Respiratory Support and Mechanisms
  • Long-Term Effects of COVID-19
  • Neonatal Respiratory Health Research
  • Hemodynamic Monitoring and Therapy
  • Radiomics and Machine Learning in Medical Imaging
  • COVID-19 Impact on Reproduction
  • Antibiotics Pharmacokinetics and Efficacy
  • Cardiac, Anesthesia and Surgical Outcomes
  • Intensive Care Unit Cognitive Disorders
  • COVID-19 and healthcare impacts
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Health and Medical Research Impacts
  • Colorectal Cancer Treatments and Studies
  • Medical Imaging Techniques and Applications
  • Vitamin C and Antioxidants Research
  • Family and Patient Care in Intensive Care Units
  • Blood Pressure and Hypertension Studies
  • Lung Cancer Diagnosis and Treatment
  • Airway Management and Intubation Techniques
  • COVID-19 and Mental Health

Intensive Care National Audit & Research Centre
2020-2022

Berry & Associates (United States)
2021

<h3>Importance</h3> Vasopressors are commonly administered to intensive care unit (ICU) patients raise blood pressure. Balancing risks and benefits of vasopressors is a challenge, particularly in older patients. <h3>Objective</h3> To determine whether reducing exposure through permissive hypotension (mean arterial pressure [MAP] target, 60-65 mm Hg) reduces mortality at 90 days ICU aged 65 years or with vasodilatory hypotension. <h3>Design, Setting, Participants</h3> A multicenter,...

10.1001/jama.2020.0930 article EN JAMA 2020-02-12

To describe critical care patients with COVID-19 across England, Wales and Northern Ireland compare them a historic cohort of other viral pneumonias (non-COVID-19) international cohorts COVID-19.Extracted data on patient characteristics, acute illness severity, organ support outcomes from the Case Mix Programme, national clinical audit for adult care, prospective (February to August 2020) are compared recent retrospective (2017-2019) COVID-19, latter identified published reports.10,834...

10.1007/s00134-020-06267-0 article EN other-oa Intensive Care Medicine 2020-10-09

<h3>Importance</h3> The optimal first-line mode of noninvasive respiratory support following extubation critically ill children is not known. <h3>Objective</h3> To evaluate the noninferiority high-flow nasal cannula (HFNC) therapy as extubation, compared with continuous positive airway pressure (CPAP), on time to liberation from support. <h3>Design, Setting, and Participants</h3> This was a pragmatic, multicenter, randomized, trial conducted at 22 pediatric intensive care units in United...

10.1001/jama.2022.3367 article EN JAMA 2022-04-07
Padmanabhan Ramnarayan Alvin Richards‐Belle Laura Drikite Michelle Saull Izabella Orzechowska and 95 more Robert Darnell Zia Sadique Julie Lester Kevin Morris Lyvonne N. Tume Peter J. Davis Mark Peters Richard Feltbower Richard Grieve Karen Thomas Paul Mouncey David A Harrison Kathy Rowan Nazima Pathan Deborah White Esther Daubney Nayan Shetty Dawn Jones Laura O'Malley Laura Rad Peter J. Davis Frances Hutchings Karen Coy Sarah Sheedy Alice Bowerman Kerry Mahoney Laura Dodge Helen Raeside Pardina Samson-Fessale Kribashnie Nundlall Jaime Carungcong Aravind S Kashyap Christine Mackerness Sarah E Daggert Rob Claydon Kirsty Mulgrew Mark Peters Ana L Pereira Tomas Holly Belfield Lauran O'Neill Gutierrez Hamza Meghari Emily Beech Gareth A. Jones Samiran Ray Saxena Rohit Hilary Klonin Remy Toko Melony Bowdler-Hayes Leanne Sherris Arshid Murad Armstrong Sonia Hebbron Kerry Szekeres Adele Avishay Sarfatti Zoe Oliver Sarah Barton Melanie James Lynda Verhulst Ivan Carlo Akash Deep Bedangshu Saikia Samira Neshat Rekha Patel S. Sukhani Karen Samm Benila Ravindranathan Vanessa Zammit Meleika Hamilton Shagun Bhatia Shah Susan E Bowes Sivakumar Oruganti Awen Evans Laura Anderson Maria Saxton Helen Fazackerley Catarina Silvestre Kamal Patel Kevin Donnelly Emma Tagliavini Vivien Richmond Helen Coutts Jessica R. Scott Ellen Smith Heather Collier Angela Aramburo Laura Alcantara Gemmar Laura Tous Sampol Jenny C Tan David K Armstrong Laura Fraser Margrethe VanDijke Ian Piper Graham Mason Danielle Pask Lara Bunni

The optimal first-line mode of noninvasive respiratory support for acutely ill children is not known.To evaluate the noninferiority high-flow nasal cannula therapy (HFNC) as acute illness, compared with continuous positive airway pressure (CPAP), time to liberation from all forms support.Pragmatic, multicenter, randomized clinical trial conducted in 24 pediatric critical care units United Kingdom among 600 aged 0 15 years who were clinically assessed require support, recruited between August...

10.1001/jama.2022.9615 article EN JAMA 2022-06-16
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