A5101759169- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Cytokine Signaling Pathways and Interactions
- Reproductive System and Pregnancy
- Multiple Sclerosis Research Studies
- Pregnancy and preeclampsia studies
- Immunotherapy and Immune Responses
- Psoriasis: Treatment and Pathogenesis
- Chemokine receptors and signaling
- Muscle and Compartmental Disorders
- Immunodeficiency and Autoimmune Disorders
- Cancer Immunotherapy and Biomarkers
- NF-κB Signaling Pathways
- Pregnancy and Medication Impact
- Cancer Mechanisms and Therapy
- Research on Leishmaniasis Studies
- Spider Taxonomy and Behavior Studies
- Viral Infections and Vectors
- MicroRNA in disease regulation
- Therapeutic Uses of Natural Elements
- Animal Diversity and Health Studies
- Immune Response and Inflammation
- Electrolyte and hormonal disorders
- Leptospirosis research and findings
- Security, Politics, and Digital Transformation
Urmia University
2015-2025
Urmia University of Medical Sciences
2015-2024
Mashhad University of Medical Sciences
2024
Tabriz University of Medical Sciences
2017-2023
Kobe University
2023
Islamic Azad University of Tabriz
2023
Shahid Rajaee Teacher Training University
2017
Ferdowsi University of Mashhad
2014
Autoimmune diseases are characterized by irregular immune responses that disrupt self-tolerance. This research explores the effects of immunomodulatory drug celecoxib on expression checkpoint receptors in monocyte-derived dendritic cells (DCs). Key receptors, including CTLA-4, VISTA, BTLA, PDL-1, B7H7, and LAG3, play critical roles initiating regulating maintaining Previous studies have highlighted significance checkpoints preventing autoimmune conditions, with animal supporting their...
Background: Behçet's Disease (BD) is a rare autoimmune disease that involves the dysfunction of regulatory T cells. FOXP3 key transcription factor in development and function T(reg) Recent studies have shown SNPs contribute to susceptibility some disorders.To clarify association between gene risk BD, 50 patients diagnosed with BD healthy controls from north-western Iran were genotyped by PCR-RFLP (Mun I Pst I) for two including rs3761547 (-3499T/C) rs3761548 (-3279 C/A) promoter region gene....
Immunological tolerance is mediated by CD4+CD25+ regulatory T (Treg) cells. Studies have shown that thymic and peripheral generations of Treg cells depend on the CD28 signaling pathway. helper 17 (Th17) are involved in pathophysiology various inflammatory diseases. Cytokines, such as interleukin (IL)-6 TGF-β, regulate reciprocal development Th17 In CD4+ cells, signal transducer activator transcription 3 (STAT3) play a critical role induction cell differentiation inhibition development.In...
Rhabdomyolysis leads to the release of myoglobin, sarcoplasmic proteins, and electrolytes into blood circulation causing acute kidney injury (AKI). Thymoquinone, a natural compound found in
Mesenchymal stem cells (MSCs) are one of the most prominent in bone marrow. MSCs can affect acute lymphocytic leukemia (ALL) under hypoxic conditions. With this aim, we used MOLT-4 as simulators ALL cocultured with marrow mesenchymal (BMMSCs) conditions vitro. Then, mRNA and protein expression MAT2A, PDK1, HK2 genes were evaluated by real-time PCR Western blot which was also followed apoptosis measurement a flow-cytometric method. Next, methylation status target investigated MS-qPCR....