Niels Wolfhagen

ORCID: 0000-0003-0573-5703
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About
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Research Areas
  • Surgical site infection prevention
  • Cardiac, Anesthesia and Surgical Outcomes
  • Surgical Sutures and Adhesives
  • Appendicitis Diagnosis and Management
  • Orthopedic Infections and Treatments
  • Intraperitoneal and Appendiceal Malignancies
  • Intestinal and Peritoneal Adhesions
  • Colorectal Cancer Surgical Treatments
  • Pressure Ulcer Prevention and Management
  • Enhanced Recovery After Surgery
  • Hernia repair and management
  • Wound Healing and Treatments
  • Ultrasound in Clinical Applications
  • Clinical practice guidelines implementation
  • Rabies epidemiology and control
  • Hemodynamic Monitoring and Therapy
  • Endometriosis Research and Treatment
  • Patient Safety and Medication Errors
  • Uterine Myomas and Treatments
  • Reconstructive Surgery and Microvascular Techniques
  • Meta-analysis and systematic reviews
  • Sepsis Diagnosis and Treatment
  • Bacterial Identification and Susceptibility Testing

University of Amsterdam
2021-2025

Amsterdam University Medical Centers
2020-2025

Tergooi
2023-2024

Collaborative Group (United States)
2024

Medtronic (Ireland)
2022

Committee on Publication Ethics
2022

Early Manuscripts Electronic Library
2022

W. L. Gore & Associates (Germany)
2022

Flevoziekenhuis
2018

The evidence on prophylactic use of negative pressure wound therapy primary closed incisional wounds (iNPWT) for the prevention surgical site infections (SSI) is confusing and ambiguous. Implementation in daily practice impaired by inconsistent recommendations current international guidelines published meta-analyses. More recently, multiple new randomised controlled trials (RCTs) have been published. We aimed to provide an overview all meta-analyses their characteristics; conduct a...

10.1016/j.eclinm.2023.102105 article EN cc-by EClinicalMedicine 2023-07-25

Abstract Background The effect of the number door openings in operating room (OR) on surgical site infections (SSI) risk remains a controversial topic. Many SSI prevention bundles include restriction maximum as intervention, often to ten per hour. However, existing evidence is limited and heterogeneous. This individual participant data (IPD) meta-analysis aims evaluate OR occurrence. Methods We searched MEDLINE (Pubmed) Embase (Ovid) up 15 January 2024, for studies investigating incidence....

10.1093/bjs/znaf024.010 article EN British journal of surgery 2025-02-01

To compare the effect of different methods bowel preparation on incidence surgical site infections (SSI), anastomotic leakage (AL), and mortality in patients undergoing elective colorectal surgery.

10.1097/as9.0000000000000175 article EN cc-by-nc-nd Annals of Surgery Open 2022-06-23

Surgical site infections (SSI) are a common postoperative complication. During the development of new WHO guidelines on SSI prevention, also in Netherlands was concluded that perioperative care could be optimised beyond current standard practice. We selected limited set readily available, cheap and evidence-based interventions from these not part practice formulated an Enhanced PeriOperative Care Health bundle (EPOCH). Here, we describe protocol for open-label, randomised controlled,...

10.1136/bmjopen-2020-038196 article EN cc-by BMJ Open 2020-05-01

Introduction Acute abdominal wound dehiscence (AWD) or burst abdomen is a severe complication after surgery with an incidence up to 3.8%. Surgical site infection (SSI) the biggest risk factor for development of AWD. It strongly suggested that use triclosan-coated sutures (TCS) closure reduces SSI. We hypothesise TCS may reduce Current randomised controlled trials (RCTs) lack power investigate this. Therefore, purpose this individual participant data meta-analysis evaluate effect on Methods...

10.1136/bmjopen-2021-054534 article EN cc-by-nc BMJ Open 2022-02-01

To determine the accuracy of final judgements doctors at emergency department (ED) and radiologists to differentiate between complicated uncomplicated acute appendicitis, because these have different treatment options.

10.1007/s00068-023-02442-2 article EN cc-by European Journal of Trauma and Emergency Surgery 2024-01-17

Abstract Background Surgical site infections (SSI) are frequent complications after elective abdominal surgery. We designed the Enhanced PeriOperative Care and Health Protection programme (EPO 2 CH) care bundle, comprising of intraoperative high fractional inspired oxygen; goal-directed fluid therapy; active preoperative, postoperative warming; glucose control treatment hyperglycaemia (> 10 mmol L − 1 ) in diabetics as well non-diabetics; wound irrigation before closure using an aqueous...

10.1186/s13063-021-05202-y article EN cc-by Trials 2021-04-21

Background: Surgical site infections (SSI) are the most common postoperative complications and substantially increase healthcare costs. There remains uncertainty which preoperative skin antiseptic solution concentration is effective. Published meta-analyses as well international guidelines show discrepancies. We compared efficacy of different preparation solutions concentrations in prevention SSI. Additionally, we provide an overview important guidelines.Methods: This systematic review...

10.2139/ssrn.4047135 article EN SSRN Electronic Journal 2022-01-01
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