- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Digital Radiography and Breast Imaging
- Radiation Dose and Imaging
- Advanced X-ray Imaging Techniques
- AI in cancer detection
- Advanced MRI Techniques and Applications
- Advanced Radiotherapy Techniques
- Cardiac Imaging and Diagnostics
- Laser-Plasma Interactions and Diagnostics
- Image and Signal Denoising Methods
- MRI in cancer diagnosis
- Advanced Image Fusion Techniques
- Cerebrovascular and Carotid Artery Diseases
- Radiomics and Machine Learning in Medical Imaging
- Photoacoustic and Ultrasonic Imaging
- Medical Image Segmentation Techniques
- Advanced Image Processing Techniques
- Cancer, Hypoxia, and Metabolism
- Digital Holography and Microscopy
- Advanced Vision and Imaging
- Bladder and Urothelial Cancer Treatments
- Advanced Electron Microscopy Techniques and Applications
- Functional Brain Connectivity Studies
- Optical Coherence Tomography Applications
Koning (United States)
2014-2020
University of Rochester
2006-2016
University of Rochester Medical Center
2006-2016
Associated Radiologists
1996
Indiana University – Purdue University Indianapolis
1996
University Medical Center
1996
University Hospital and Clinics
1996
University of Utah
1987-1989
Developing and optimizing an x-ray scatter control reduction technique is one of the major challenges for cone beam computed tomography (CBCT) because CBCT will be much less immune to than fan-beam CT. X-ray reduces image contrast, increases noise introduces reconstruction error into CBCT. To reduce interference, a practical algorithm that based upon stop array sequence processing has been developed on flat panel detector-based prototype scanner. This paper presents array-based correction...
X‐ray projection mammography, using a film/screen combination, or digital techniques, has proven to be the most effective imaging modality currently available for early detection of breast cancer. However, inherent superimposition structures makes small carcinoma (a few millimeters in size) difficult detect when it is occult dense breasts, leading high false‐positive biopsy rate. Cone‐beam x‐ray‐projection‐based volume flat panel detectors (FPDs) may allow obtaining three‐dimensional images,...
Cone-Beam CT for Breast Imaging: Radiation Dose, Coverage, and Image QualityAvice O'Connell1, David L. Conover1, Yan Zhang1, Posy Seifert2, Wende Logan-Young2, Chuen-Fu Linda Lin1, Lawrence Sahler1 Ruola Ning1Audio Available | Share
Preliminary evaluation of recently developed large-area flat panel detectors (FPDs) indicates that FPDs have some potential advantages: compactness, absence geometric distortion and veiling glare with the benefits high resolution, detective quantum efficiency (DQE), frame rate dynamic range, small image lag (<1%), excellent linearity (/spl sim/1%). The advantages new FPD make it a promising candidate for cone-beam volume computed tomography (CT) angiography (CBVCTA) imaging. purpose this...
It was recently reported that the real-time flat panel detector-based cone-beam computed tomography (CBCT) breast imaging can help improve detectability of small tumors with an X-ray dose comparable to conventional mammography. In this paper, efficient denoising algorithm is proposed further reduce exposure level required by a CBCT scan acquire acceptable image quality. The wavelet-based possesses three significant characteristics: 1) wavelet coefficients at each scale are classified into...
Breast CT provides image volumes with isotropic resolution in high contrast, enabling detection of small calcification (down to a few hundred microns size) and subtle density differences. Since breast is sensitive x-ray radiation, dose reduction an important topic, for this purpose, few-view scanning main approach. In article, we propose Deep Efficient End-to-end Reconstruction (DEER) network reconstruction. The major merits our include efficiency, excellent quality, low model complexity. By...
With separability assumed, we decompose a three-dimensional point spread function (3D PSF) into two-dimensional (2D) PSFs and further one-dimensional (ID) PSFs. Based on the observation of location invariance step edge under convolution, propose rectification procedure to automatically establish step-edge from blurred profile. The ID PSF is modelled as single-parameter Gaussian function, which determined by iteratively blurring A plastic solid ball (diameter approximately 6 mm) used provide...
The application of x‐ray flat panel imagers (FPIs) in cone beam volume CT (CBVCT) has attracted increasing attention. However, due to a deficient semiconductor array manufacturing process, defective cells unavoidably exist FPIs. These cause their corresponding image pixels projection behave abnormally signal gray level, and result severe streak ring artifacts CBVCT reconstructed from the images. Since three‐dimensional (3‐D) back‐projection is involved CBVCT, formation different that...
This paper presents a very efficient algorithm for image denoising based on wavelets and multifractals singularity detection. A challenge of is how to preserve the edges an when reducing noise. By modeling intensity surface noisy as statistically self-similar multifractal processes taking advantage multiresolution analysis with wavelet transform exploit local statistical self-similarity at different scales, pointwise strength value characterizing each scale was calculated. thresholding...
Although x-ray mammography is widely developed for breast tumour detection, it suffers from spatial superposition in its two-dimensional (2D) representation of a three-dimensional (3D) structure. Accordingly, 3D imaging, such as cone-beam computed tomography (CT), arises at the historic moment. In this paper, we theoretically elucidate effect associated with on detection. This explanation based line integral traversing composite model. As result, can characterize difficulty detecting small...
The purpose of the study is to characterize imaging performance recently built novel cone beam breast CT (CBBCT) scanner. This CBBCT scanner system has one x-ray source and flat panel detector (Varian's PaxScan 4030CB) mounted on a rotating assembly. A patient table above tube/detector hole through it that allows woman's hang pendant in volume at rotation axis. assembly rotates around axis acquires multiple 2D projection images uncompressed located 10 seconds. Slip ring technology continuous...
The Noise Power Spectrum (NPS) is a function that yields information about the spatial frequency composition of noise in images obtained by system. It evaluated calculating absolute value squared image and normalizing it with respect to voxel matrix sizes. Consequently, NPS has been one physical characteristics commonly used quantitatively measure performance In this article, we Cone Beam CT Breast Imaging system considering following factors. First, its symmetry around x- y-axis along...
Cone beam computed tomography (CBCT) has been investigated in the past two decades due to its potential advantages over a fan CT. These include (a) great improvement data acquisition efficiency, spatial resolution, and resolution uniformity, (b) substantially better utilization of x‐ray photons generated by tube compared CT, (c) significant advancement clinical three‐dimensional (3D) CT applications. However, most studies CBCT are focused on cone theories reconstruction algorithms. The...
Developing and optimizing an x-ray scatter control reduction technique is one big challenge for cone beam volume computed tomography (CBVCT) because CBVCT will be much less immune to than fan-beam CT. X-ray Scatter reduces image contrast, increases noise introduces reconstruction error into CBVCT. To reduce interference, a practical algorithm that based upon the stop array sequence processing has been developed on flat panel detector-based prototype scanner. This paper presents array-based...
In cone-beam computerized tomography (CT), projections acquired with the focal spot constrained on a planar orbit cannot provide complete set of data to reconstruct object function exactly. There are severe distortions in reconstructed noncentral transverse planes when cone angle is large. this work, new method proposed which can obtain by acquiring along circle-plus-arc orbit. A reconstruction algorithm using developed, based Radon transform and Grangeat's formula. This first transforms...
The circle‐plus‐arc orbit possesses advantages over other “circle‐plus” orbits for the application of x‐ray cone beam (CB) volume CT in image‐guided interventional procedures requiring intraoperative imaging, which movement patient table is to be avoided. A CB circle‐plus‐two‐arc satisfying data sufficiency condition and a filtered backprojection (FBP) algorithm reconstruct longitudinally unbounded objects presented here. In circle suborbit, employs Feldkamp's formula another FBP...
Rationale and Objectives.A prototype volume computed tomography (CT) system for use in angiography was designed, constructed, tested.The consisted of a fixed X-ray tube, conventional image intensifier (II) coupled to charge-coupled device camera, computer-controlled turntable on which phantoms were placed.We wanted predict, through phantom studies, the imaging performance an IPbased CT direct three-dimensional (3D) reconstruction vascular structures. Methods.To explore reconstructing...
This present study reports the results of a computer simulation whose aim was to predict low‐contrast imaging performance which conventional x‐ray image intensifier with charge coupled device (CCD) camera would be capable if incorporated into computed tomography (CT) volume imager. A vascular task modeled in our simulation. The effects detector noise, exposure levels, analog‐to‐digital conversion (ADC) precision and residual levels detected scatter were considered. this indicate that an...
The sensitivity to detect small breast cancers and the specificity of conventional mammography (CM) remain limited owing an overlap in appearances lesions surrounding structure. We propose address limitations accompanying CM using flat panel detector (FPD)-based cone beam CT imaging (CBCTBI). purpose study is determine optimal x-ray operation ranges for different sizes normal breasts corresponding glandular dose levels. current CBCT prototype consists a modified GE HighSpeed Advantage...
X-ray computed tomography (CT) reconstructs cross-sectional images from projection data. However, ionizing radiation associated with CT scanning might induce cancer and genetic damage. Therefore, the reduction of dose has attracted major attention. Few-view image reconstruction is an important topic to reduce dose. Recently, data-driven algorithms have shown great potential solve few-view problem. In this paper, we develop a dual network architecture (DNA) for reconstructing directly...
X-ray projection mammography, using a film/screen combination or digital techniques, has proven to be the most effective imaging modality for early detection of breast cancer currently available. However, inherent superimposition structures makes small carcinoma (a few millimeters in size) difficult detect occultation case dense breasts, resulting high false positive biopsy rate. The cone-beam x-ray based volume flat panel detectors (FPDs) it possible obtain three-dimensional images. This...
Conventional film-screen mammography is the most effective tool for early detection of breast cancer currently available. However, conventional has relatively low sensitivity to detect small cancers (under several millimeters) owing an overlap in appearances benign and malignant lesions, surrounding structure. The limitations accompanying be addressed by incorporating a cone beam CT imaging technique with recently developed flat panel detector. Computer simulation preliminary studies have...