A5113055033- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- Economic and Financial Impacts of Cancer
- Diverticular Disease and Complications
- COVID-19 Clinical Research Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Dialysis and Renal Disease Management
- Multiple and Secondary Primary Cancers
- Bariatric Surgery and Outcomes
- Abdominal Trauma and Injuries
- Metastasis and carcinoma case studies
- Palliative Care and End-of-Life Issues
- COVID-19 diagnosis using AI
- Pancreatic and Hepatic Oncology Research
- Cerebrovascular and Carotid Artery Diseases
- COVID-19 and healthcare impacts
- Eosinophilic Esophagitis
- Eosinophilic Disorders and Syndromes
- ATP Synthase and ATPases Research
- Power Systems Fault Detection
- Infectious Diseases and Tuberculosis
- Cardiovascular Health and Risk Factors
- Neurological disorders and treatments
University of Cincinnati
2025
Hurley Medical Center
2023-2024
Michigan State University
2023-2024
Mayo Clinic
2019-2024
University of Cincinnati Medical Center
2024
McLaren Regional Medical Center
2024
WinnMed
2024
All India Institute of Medical Sciences Rishikesh
2021-2023
University at Albany, State University of New York
2023
Nepalese Army Institute of Health Services
2021-2022
Myc hyperactivation coordinately regulates numerous metabolic processes to drive lymphomagenesis. Here, we elucidate the temporal and functional relationships between medley of pathways, factors, mechanisms that cooperate control redox homeostasis in Myc-overexpressing B cell lymphomas. We find overexpression rapidly stimulates oxidative pentose phosphate pathway (oxPPP), nucleotide synthesis, mitochondrial respiration, which collectively steers cellular equilibrium a more state. identify...
Abstract The phosphoribosyl pyrophosphate synthetase (PRPS) enzyme conducts a chokepoint reaction connecting central carbon metabolism and nucleotide production pathways, making it essential for life 1,2 . Here, we show that the presence of multiple PRPS-encoding genes is hallmark trait eukaryotes, trace evolutionary origins define individual functions each five mammalian PRPS homologs – three isozymes (one testis-restricted) 3,4 two non-enzymatic associated proteins (APs) 5,6 which...
Abstract BACKGROUND Eosinophilic colitis (EoC) is a rare gastrointestinal inflammation of the colon due to an altered hypersensitivity reaction characterized by eosinophilic infiltration into colonic wall. Patients usually present with abdominal pain, diarrhea, and weight loss. METHODS We used National Inpatient Sample (NIS) database conduct retrospective study hospitalized adult patients using validated ICD-10 diagnosis codes between January 1, 2016, December 31, 2020. RESULTS identified...
Botulism is a neuroparalytic syndrome resulting from the systemic effects of an exoneurotoxin produced by gram-positive, rod-shaped, spore-forming, obligate anaerobic bacterium Clostridium botulinum. Here, we present case 40-year-old male, presenting with sudden onset abdominal pain associated vomiting. He was admitted for conservative management once CT abdomen and pelvis revealed partial small bowel obstruction no signs perforation or ischemia. However, next day, patient had cardiac arrest...
A 27-year-old female patient initially presented with fever, myalgia, sore throat that progressed to multifocal pneumonia, and cerebral sinus venous thrombosis. combination of upper respiratory symptoms tooth infection, positive blood culture for Fusobacterium nucleatum, computed tomography (CT) chest finding magnetic resonance imaging (MRI) internal jugular vein thrombosis (IJVT) (CVST) suggested Lemierre syndrome. The was managed fluids, antibiotics, anticoagulants. survived discharged...
Delayed Splenic Rupture (DSR) is a rare but well-known presentation of Blunt Injury (BSI), most which occur due to motor accidents, fall from height or direct blow the left thorax abdomen. Here we present case DSR five days after trivial trauma.A 37-year-old female presented with pain in left-hypochondrium an accidental bump against furniture at home. Initially, it was grade III splenic injury upon arrival our hospital her hometown had progressed IV. Since patient hemodynamically stable,...
Background: There is a high risk of occupational exposure to tuberculosis among healthcare workers in endemic countries. Regular screening for not carried out Nepal. Infection control measures are also routinely implemented. The aim this study was determine the prevalence active staff/students at Patan Hospital.Methods: Participants were given self-administered questionnaire and invited undergo chest radiography. Cases scored reviewed based on predetermined criteria, presumptive cases sputum...
Abstract Subclavian Steal Syndrome (SSS) is a rare vascular syndrome caused due to proximal occlusion or stenosis of subclavian innominate artery. It usually asymptomatic but occasionally may present with vertebro‐basilar insufficiency and/or upper limb ischemia. Atherosclerosis the most common cause.
Novel coronavirus disease 2019 (COVID-19) pandemic was originated in Wuhan, China, December 2019. So far, more than 4 million people worldwide have been infected with the virus. Various manifestations of reported since began. Among them, acute abdomen is one COVID-19. Some studies pancreatitis several patient due to COVID-19 infection. In this study, we report a rare case whom SARS-CoV-2 caused severe hemorrhagic necrotizing pancreatitis.
Colorectal cancer progresses without any symptoms early on or those clinical are very discrete and so undetected for long periods of time. Complicated colorectal carcinoma has several symptoms, the most common being bleeding obstruction. Occasionally, it will cause perforation, which carries a worse prognosis. It is rare colon to present as abscess anterior abdominal wall that forms result direct invasion perforation by cancer. We hereby report an unusual case perforated presented infiltrating wall.
Symptomatic pleural effusion secondary to pleuroperitoneal communication in patients undergoing peritoneal dialysis (PD) occurs approximately 2% of continuous ambulatory PD. The classic presentation is that a low-protein, high-glucose aspirate consistent with the high dextrose concentrations present standard PD fluids, hence name sweet hydrothorax. Nevertheless, increasing use icodextrin calls for an innovative bedside diagnostic approach because does not contain after all. We describe...
Gallstone ileus is a rare complication of cholelithiasis seen in patients with long history cholelithiasis. It occurs more the older age group and female gender. These have poor general condition therefore selection appropriate treatment difficult. The clinician has to make decision between immediate one-stage or two-stage closure cholecysto-intestinal fistula waiting for natural closure. We discussed management cause small bowel obstruction due untreated
Jejunal diverticulum is a very rare disease. Diagnosis of this condition challenge owing to non-specific complaints the patient. Fifteen percent cases jejunal diverticula present with acute abdomen. Approximately 77% small bowel diverticular disease occur multiple diverticula. Here we describe case complicated isolated presenting perforation, which was successfully treated resection involved segment anastomosis.
A gastrointestinal stromal tumor is a rare of mesenchymal origin. We present case 32-year-old male patient with history iron deficiency anemia who presented nocturnal cramping abdominal pain, nausea, non-bloody vomiting, loss appetite, and weight loss. The had no significant family cancer. Prior imaging showed gastric distension chronic inflammatory changes, but scheduled esophagogastroduodenoscopy (EGD) was not done due to follow-up. On admission, the tachycardic anemia. An CT scan new...
Methods: Data were collected using Surveillance, Epidemiology, and End Results, SEERS at 8.4.2 database Incidence-Based Mortality. The analysis included 17 SEER Registries data from 2000 to 2020. Selection criteria malignant breast cancer cases with known ages. Age-adjusted rates displaced as per 100,000, standardized the US Standard Population confidence intervals (95% Tiwari modification), standard errors calculated. Results: Our study a total of 25,027 related ischemic heart disease....