A5002853643- Atrial Fibrillation Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Intensive Care Unit Cognitive Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrhythmias and Treatments
- Venous Thromboembolism Diagnosis and Management
- Thyroid Disorders and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Anesthesia and Neurotoxicity Research
- Traumatic Brain Injury and Neurovascular Disturbances
Copenhagen University Hospital
2023-2025
Rigshospitalet
2023-2025
Frederiksberg Hospital
2018-2020
University of Copenhagen
2018-2020
There is increasing interest in heart rhythm monitoring and technologies to detect subclinical atrial fibrillation (AF), which may lead incidental diagnosis of bradyarrhythmias.To assess bradyarrhythmia prevalence prognostic significance persons screened for AF using implantable loop recorder (ILR) compared with unscreened persons.This was a post hoc analysis the Implantable Loop Recorder Detection Atrial Fibrillation Prevent Stroke (LOOP) randomized clinical trial, took place 4 sites...
Background Atrial fibrillation (AF) prevalence is rising; however, data on the bleeding risks associated with detection of subclinical AF are needed. Objective Our objective was to determine increment implantable loop recorder (ILR) screening for and subsequent anticoagulation initiation compared usual care. Methods This post hoc study utilized LOOP trial from 6,004 elderly patients stroke randomized either ILR (n = 1,503) or care 4,503). The mean follow-up time 64.5 months, none were lost...
Abstract Context Subclinical thyroid dysfunction is a marker for atrial fibrillation (AF) and stroke risk. Objective This study explored the effects of AF screening according to thyroid-stimulating hormone (TSH) levels. Methods An trial (the LOOP study) was analyzed post hoc baseline TSH. The primary outcome or systemic embolism (SE). Secondary outcomes included major bleeding, all-cause death, combination stroke, SE, cardiovascular death. Results TSH measurements were available in 6003 6004...
Background Perioperative hyperoxia has been linked to increased long‐term mortality. Vasoconstrictive and cellular side effects have suggested increase the risk of coronary cerebral ischemia. The aim this post‐hoc analysis a large randomized trial was compare 80% vs 30% perioperative oxygen on stroke or transient ischemia ( TCI ) in patients undergoing abdominal surgery. Methods A total 1386 were during acute elective open Median follow‐up 3.9 years. Primary outcome composite occurrence ....
Abstract Background Screening for atrial fibrillation (AF) is rising, yet trials have failed to show efficacy stroke prevention from screening and subsequent anticoagulation. Quality of life an important outcome patients physicians, however, it largely unknown how this affected by AF. The adverse effects should be considered before implementing systematic screening. Purpose To explore changes in quality associated with AF anticoagulant treatment upon detection. Methods We used data 6,004...
Abstract Background Atrial fibrillation (AF) prevalence is rising, strongly aided by population ageing and increased awareness. Detection treatment of subclinical AF may help mitigate stroke risk, but could increase iatrogenic complications. Purpose To evaluate whether detection using implantable loop recorder (ILR) subsequent initiation oral anticoagulant (OAC) enhances the risk major bleeding in elderly individuals with factors. Methods This was a post-hoc analysis trial which randomised...