- Reconstructive Surgery and Microvascular Techniques
- Head and Neck Cancer Studies
- Facial Trauma and Fracture Management
- Bone fractures and treatments
- Cancer Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Reconstructive Facial Surgery Techniques
- Orthopedic Infections and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Bone and Joint Diseases
- Bone health and treatments
- Electrospun Nanofibers in Biomedical Applications
- Orthopaedic implants and arthroplasty
- Medical Imaging Techniques and Applications
- Dental Implant Techniques and Outcomes
- Ear and Head Tumors
- Tracheal and airway disorders
- Tissue Engineering and Regenerative Medicine
- Facial Nerve Paralysis Treatment and Research
- Periodontal Regeneration and Treatments
- Brain Metastases and Treatment
- Mesenchymal stem cell research
- Oral health in cancer treatment
- Surgical Simulation and Training
- Traumatic Ocular and Foreign Body Injuries
Charité - Universitätsmedizin Berlin
2017-2025
Humboldt-Universität zu Berlin
2017-2025
Freie Universität Berlin
2007-2025
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2024-2025
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
2016-2020
University Medical Center Hamburg-Eppendorf
2016-2018
Orthopädische Universitätsklinik
2018
Düsseldorf University Hospital
2018
Heinrich Heine University Düsseldorf
2018
Smith College
2017
Polychrome sequential labeling with fluorochromes is a standard technique for the investigation of bone formation and regeneration processes in vivo. However, human application, only tetracycline its derivates are approved as fluorochromes. Therefore, aim this study was to determine fluorescence characteristics different assess feasibility vivo using distinguishable Eight were injected subcutaneously into growing rats single dose or sequentially combinations. After preparation resin-embedded...
Background This study was conducted to evaluate the feasibility, clinical outcomes, and accuracy of patient-specific 3D-printed miniplates for mandible reconstruction with fibula free flaps. Methods A feasibility 8 patients. Following virtual planning, 1.0 mm titanium non-locking were produced via laser selective melting. cutting drilling guides used segmental resection flap harvesting. Flap fixation performed two 4-hole 2.0 screws (screw length 7 mm) each intersegmental gap. Clinical...
Several studies suggest an estrogen receptor alpha (ERα)-mediated influence on the pathogenesis of oral squamous cell carcinoma (OSCC), as described for other malignancies that are not considered to be primarily hormone-dependent. Recently, association between ERα expression and improved survival in oropharyngeal (OPSCC) has been found. However, prognostic relevance OSCC proven date. Therefore, aim this study was evaluate a large patient cohort analyze its recurrence.A total 316 patients...
Different parameters have been identified in patients with oral squamous cell carcinomas (OSCC) that a serious impact on survival, including residual tumour and extracapsular spread. Moreover, other factors, the lymph node ratio (LNR) yield (LNY), suggested as prognostic markers.This retrospective study included diagnosed OSCC cervical metastases during years 2010-2020. Patients' records were evaluated regarding status, final therapy regime, recurrence, time to death, association...
(1) Background: Evaluation of impact adjuvant radiation therapy (RT) in patients with oral squamous cell carcinoma the cavity/oropharynx (OSCC) up to 4 cm (pT1/pT2) and solitary ipsilateral lymph node metastasis (pN1). A non-irradiated group clinical follow-up was chosen for control, survival quality life (QL) were compared; (2) Methods: This prospective multicentric comprehensive cohort study included resected OSCC (pT1/pT2, pN1, cM0) who allocated into or observation. The primary endpoint...
Rat fracture models are extensively used to characterize normal and pathological bone healing. Despite, systematic research on inter- intra-individual differences of common rat bones examined is surprisingly not available. Thus, we studied the biomechanical behaviour radiological characteristics humerus, tibia femur male Wistar rat—all which potentially available in experimental situation—to identify useful or detrimental properties each facilitate sample size calculations. 40 paired femura,...
Retrospective study of all patients presented at our emergency department after an accident while riding e-scooter between 15 June 2019 and December 2019. Out this group, we subgrouped with injuries to the head neck area.Shared systems have recently been introduced in many big cities worldwide are becoming increasingly popular. This retrospective aimed give a detailed overview clinical data on consequences accidents, particular attention maxillofacial point view.We performed single-center...
Pseudarthrosis after mandibular reconstruction leads to chronic overload of the osteosynthesis and impedes dental rehabilitation. This study evaluates impact gap site on osseous union in mandible using a new volumetric analysis method with repeated cone-beam computed tomography (CBCT).The degree bone regeneration was evaluated 16 patients fibula free flap patient-specific plates. Percentual volume width changes intersegmental gaps were retrospectively analyzed baseline CBCT comparison...
Miniplates offer superior clinical handling and facilitate postoperative removal after mandibular reconstruction but unfavorable load distribution under high stress has been shown. This study aimed to compare the outcome of patient-specific 3D-printed (PS-3D) titanium miniplate with plate fixation in three-segmental LCL-type reconstructions for first time.