A5074763729- Medical Research and Treatments
- Corporate Social Responsibility Reporting
- RNA modifications and cancer
- Stroke Rehabilitation and Recovery
- Ferroptosis and cancer prognosis
- Cancer Genomics and Diagnostics
- Bladder and Urothelial Cancer Treatments
- Advanced Neuroimaging Techniques and Applications
- Environmental Sustainability in Business
- Cancer Immunotherapy and Biomarkers
- Immune Cell Function and Interaction
- Lung Cancer Treatments and Mutations
- Cerebral Palsy and Movement Disorders
- Transcranial Magnetic Stimulation Studies
- Cancer-related Molecular Pathways
- Immunotherapy and Immune Responses
- DNA Repair Mechanisms
- Neurological Disease Mechanisms and Treatments
- Sustainable Supply Chain Management
- Epigenetics and DNA Methylation
- Innovation Policy and R&D
- PARP inhibition in cancer therapy
- Balance, Gait, and Falls Prevention
Shanghai University of Sport
2024
Hefei University of Technology
2023-2024
The Fourth People's Hospital of Zibo City
2020
Tianjin Medical University Cancer Institute and Hospital
2020
Fudan University Shanghai Cancer Center
2019
Shanghai Medical College of Fudan University
2019
Baotou Central Hospital
2013
BGI Group (China)
2012
This paper uses Chinese small and medium enterprises (SMEs) as a research sample to explore the relationship between environment, social responsibility, governance (ESG) performance firm value creation test moderating effect of government subsidies. In addition, we classify subsidies into innovation, development using Biterm Topic Model (BTM) heterogeneous effects. The results show an inverted U-shaped ESG in SMEs. Government have significant on curve creation, different also varies. An...
Background Nowadays, immunotherapy targeting immune checkpoint receptors is one of the cornerstones systemic treatment in melanoma. Homologous recombination repair (HRR) DNA damage response (DDR) pathways, which has been proved to correlate with efficacy platinum-based chemotherapy, PARP inhibitor therapy, and a variety cancers. However, their predictive value HRR remained unknown patients advanced Methods Data melanoma from an independent cohort (Samstein2018) were used analyze correlation...
In the context of global sustainable development, relationship between environmental, social responsibility, and governance (ESG) performance multi-stakeholder value creation has been widely discussed. However, there is a complex causal ESG creation, many firm characteristics are involved, no systematic study on them. this study, we aim to explore joint role firms’ internal external in relationship, how three components act through their various configurations. To identify relationships...
PALB2, a gene in the homologous recombination repair (HRR) pathway of DNA damage response (DDR), is associated with efficacy platinum-based chemotherapy, immunotherapy, and PARP inhibitor therapy several tumors. However, PALB2 characteristics, its correlation immunotherapy biomarker, prognostic effect non-small cell lung cancer (NSCLC) were unknown.Tumor tissue samples from advanced Chinese NSCLC patients analyzed by next-generation sequencing (NGS) (panel on 381/733-gene). Tumor mutation...
The incidence of lung cancer is growing fast in China, however, the prognosis remains dismal due to limited therapeutic approaches. "ret proto-oncogene mutation" (RET) fusions have been proven be driver gene development and target several multi-target tyrosine kinase inhibitors.We applied formalin-fixed, paraffin-embedded (FFPE) samples 39 patients with non-small cell (NSCLC) using Lung Plasma panel covering 168 cancer-associated genes performed capture-based targeted deep sequencing...
Background The process of aging often accompanies a decline in cognitive function, postural control, and gait stability, consequently increasing the susceptibility to falls among older individuals. In response these challenges, motor-cognitive training has emerged as potential intervention mitigate age-related declines. Objective This study aims assess acute effects two distinct modalities, treadmill dual-task (TMDT) interactive (IMCT), on walking ability, performance elderly population....
Abstract Bladder cancer is the ninth most common worldwide, with TCC being predominant form (90%). We completed a preliminary research that investigated into exomes of 9 TCCs and target genes additional TCCs, discovered frequent aberrations chromatin remodeling genes. Six genes, including UTX, MLL/MLL3, CREBBP/EP300, NCOR1, ARID1A CHD6, were identified in 59% 97 patients. Here, order to obtain more comprehensive genetic overview TCC, we sequenced both whole genomes for another 92 samples....
Abstract Background: Malic enzyme 1 (ME1) catalyzes malate to pyruvate and thus promotes glycolysis, playing a part in the Warburg effect. Recently, several researches have revealed its crucial role cancer metastasis. KM-plotter, an online analysis tool, showed high ME1 mRNA level was related poorer RFS OS. Herein, we explore prognostic effect of on invasive breast Chinese patients metastasis vitro. Methods: 220 with early were included this study. expression evaluated semi-quantitatively...
Objective: To explore the nursing effect of standardized interventions in endoscopic examination patients with gastric ulcer complicated diabetes. Methods: 90 diabetes who were treated our hospital from May 2018 to 2019 selected and randomly divided into 2 groups, each containing 45. The control group received routine nursing, observation performed intervention on basis group. conventional After two groups compared for their psychological state satisfaction. Results: HAMD HAMA scores lower...
Objective: To explore the effect of targeted nursing based on basic living care patients with chronic gastric ulcer. Method: Ninety ulcer treated in our hospital from August 2018 to 2019 were selected and divided into observation group (n = 45) control randomly. The was given routine care. On basis group, Compare compliance behavior two groups. Results: After intervention, score higher than that difference statistically significant (P<0.05). Conclusion: use for can improve their behavior,...