A5004020341- Nanoplatforms for cancer theranostics
- Photodynamic Therapy Research Studies
- Porphyrin and Phthalocyanine Chemistry
- Nanoparticle-Based Drug Delivery
- Advanced Photocatalysis Techniques
- Nanocomposite Films for Food Packaging
- 2D Materials and Applications
- Antimicrobial agents and applications
- Protein Interaction Studies and Fluorescence Analysis
- MXene and MAX Phase Materials
- Quantum Dots Synthesis And Properties
- Molecular Sensors and Ion Detection
- Gold and Silver Nanoparticles Synthesis and Applications
- Metal complexes synthesis and properties
- Electrospun Nanofibers in Biomedical Applications
- Polysaccharides and Plant Cell Walls
- Antifungal resistance and susceptibility
- Chalcogenide Semiconductor Thin Films
- Natural Compound Pharmacology Studies
- biodegradable polymer synthesis and properties
- Graphene and Nanomaterials Applications
- Wound Healing and Treatments
- Transition Metal Oxide Nanomaterials
- Advanced Drug Delivery Systems
- Radiopharmaceutical Chemistry and Applications
Ege University
2020-2024
For synthesizing metal–organic molecules with pro‐drug properties to prevent the accumulation of amyloid beta (Aβ 1–42 ), which is a feature neurodegenerative Alzheimer's disease, two new Schiff bases imine/amine donors 2‐([3,3‐diphenylalidene]amino)‐N,N‐dimethylethane‐1‐amine and N,N‐dimethyl‐2‐([quinolin‐4‐ylmethylene]amino)ethane‐1‐amine, as well their novel Pt (II) complexes (I II), were synthesized characterized via Fourier transform infrared spectroscopy, 1 H‐ 13 C‐nuclear magnetic...
Triple-negative breast cancer (TNBC) tends to behave more aggressively compared other subtypes due the lack of receptors and its limited targeting therapy. In recent years, nanotechnology advancement has led development various nanoparticle platforms for targeted treatment cancers. Especially, HSA-NPs have specific advantages such as biocompatibility, adjustable size during production, relatively easy synthesis. this study, were encapsulated with docetaxel (DTX) functionalized polyethylene...
This study presents the development and evaluation of a DFO@mAb-NP (DFO@Durvalumab-HSA-DTX nanoparticle) nanoplatform for imaging in triple-negative breast cancer (TNBC). The demonstrated significant changes postconjugation with DFO, evidenced by increased particle size from 178.1 ± 5 nm to 311 26 zeta potential alteration -31.9 3 mV -40.5 0.8 mV. Fourier-transform infrared spectroscopy ultraviolet spectral analyses confirmed successful DFO conjugation, notable shifts peak wavelengths. High...
Glioblastoma multiforme (GBM) is an aggressive and fatal brain tumor that tends to occur in older adults has several subtypes. The fact the mechanisms of initiation progression glioblastoma are not yet known obstacle treatment disease. For this reason, studies have been carried out recent years develop new therapeutic approaches. Photodynamic therapy (PDT) a procedure approved considered safe most clinical trials. With help photosensitizer (PS), growth regression promoted, aiming prolong...
In this study, two SiPcs have been selected and the photodynamic therapy potentials were evaluated of Pcs. Synthesis Axially 2-decyn-1-oxy disubstituted Es-SiPc-2 was newly synthesized by reaction SiPcCl 2 with 2-decyn-1-ol in presence NaH toluene. Furthermore, their nuclear imaging human colon adenocarcinoma (HT-29) lung fibroblast cell (WI-38) lines. The uptake results indicated that Es-SiPc labeled [Formula: see text]I radionuclide ([Formula: text]I-Es-SiPc) approximately 2-fold higher...