A5031256678- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
- Heart Failure Treatment and Management
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Infective Endocarditis Diagnosis and Management
- Cardiovascular and exercise physiology
- Cardiovascular Health and Disease Prevention
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Chemotherapy-induced cardiotoxicity and mitigation
- Heart Rate Variability and Autonomic Control
- Advanced MRI Techniques and Applications
- Antimicrobial Resistance in Staphylococcus
- Blood Pressure and Hypertension Studies
- Cardiac Arrhythmias and Treatments
- Electrolyte and hormonal disorders
- Pericarditis and Cardiac Tamponade
- Viral Infections and Immunology Research
- Lipoproteins and Cardiovascular Health
- Cardiac Structural Anomalies and Repair
- Pulmonary Hypertension Research and Treatments
- Diabetes Treatment and Management
- Renal function and acid-base balance
Nagoya City University
2015-2025
Nagoya University
2024-2025
University Hospital Centre Zagreb
2022
University of Zagreb
2022
National University Heart Centre Singapore
2022
National University of Singapore
2022
Mizuho (Japan)
2012-2021
Lithuanian University of Health Sciences
2019
Institute of Clinical and Experimental Medicine
2019
Although higher red cell distribution width (RDW) has recently been reported to be associated with increased mortality independent of anemia in patients heart failure and those coronary artery disease (CAD), the mechanism underlying this association is unknown. We hypothesized that RDW may reflect neurohumoral activation a chronic inflammatory state each contribute adverse clinical outcomes these populations. measured plasma levels B-type natriuretic peptide (BNP) high-sensitive C-reactive...
Heart failure with preserved ejection fraction (HFpEF) is frequently observed in older women. Increased arterial stiffness this population may be a cause of HFpEF.In 75 patients who underwent cardiac catheterization and had no significant coronary artery stenosis or left ventricular (LV) wall motion abnormalities, the LV relaxation time constant (Tp) was calculated. The LVEF obtained from ventriculography, plasma brain natriuretic peptide (BNP) level measured. From pressure waveforms at...
To establish an imaging-based method to quantify left ventricular (LV) diastolic pressures. In 115 patients suspected of coronary artery disease, LV pressure was measured by micromanometers and images echocardiography. filling as pre-atrial contraction (pre-A PLV). Based on previous observations we hypothesized that pre-A PLV approximates the sum minimum maximum transmitral difference. Parameters used for estimates included volumes strain, atrial mitral flow velocities, systolic arterial...
Abstract Background There is a clinical need in heart failure diagnostics to have non-invasive measure of left ventricular (LV) filling pressure. Echocardiographic parameters may be used differentiate between normal and elevated pressure, but do not provide quantitative estimate the Purpose To establish method for estimating LV pressure construction diastolic curve. Methods Retrospective study 100 patients with suspected coronary artery disease. Ground truth (i.e. pre-atrial contraction...
Background:Speckle-tracking echocardiography (STE)-derived parameters may have better correlation with left ventricular (LV) relaxation and filling pressure than tissue Doppler-derived parameters. However, it has not been elucidated which parameter – strain or rate direction of myocardial deformation longitudinal circumferential is the most useful marker LV pressure.Methods Results:We conducted a prospective multicenter study compared Doppler- STE-derived time constant decay (τ) mean...
Background: Although left ventricular (LV) diastolic dysfunction is associated with increased risk for incident heart failure in patients coronary artery disease (CAD), no specific treatment abnormalities has been established. Animal and small human studies have shown that an acute increase LV afterload adversely impacts on early relaxation, but little known about its chronic effect function. Methods Results: The relationships of various components arterial load (arterial compliance, total...
Based on our previous observation, inertia stress (IS) of late systolic aortic flow was often observed in left ventricles with relatively higher ventricular (LV) ejection fraction (EF). Most lower LVEF did not have IS. Accordingly, lack IS may correlate LV diastolic dysfunction through the loss elastic recoil and contribute to pathogenesis heart failure (HF) reduced survival. We enrolled 144 consecutive patients that underwent cardiac catheterization for diagnosis coronary artery disease....
We hypothesized that left ventricular (LV) diastolic dysfunction assessed by cardiac catheterization may be associated with increased risk for cardiovascular events. To test the hypothesis, we function (relaxation time constant (Tau) and end-diastolic pressure (EDP)) as well Doppler echocardiography (early mitral annular velocity (e') a ratio of early inflow to velocities (E/e')) in 222 consecutive patients undergoing coronary artery disease (CAD). During followup 1364 ± 628 days, 5 deaths...
Background: Diagnosis of left ventricular (LV) diastolic dysfunction by blood testing is expedient in the clinical setting. Methods and Results: In 98 patients with LV ejection fraction ≥50% who underwent cardiac catheterization for evaluation coronary artery disease, pressure (LVP) was measured using a catheter-tipped micromanometer. A time constant, τ, relaxation computed from LVP decay; inertia force (IF) late systolic aortic flow, surrogate index elastic recoil, also LVP−dP/dt relation...