A5063443142- Plant Pathogens and Fungal Diseases
- Allelopathy and phytotoxic interactions
- Chemical synthesis and alkaloids
- Microbial Natural Products and Biosynthesis
- Plant Parasitism and Resistance
- Plant-Microbe Interactions and Immunity
- Fungal Biology and Applications
- Alkaloids: synthesis and pharmacology
- Phytochemistry and Biological Activities
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Essential Oils and Antimicrobial Activity
- Forest Insect Ecology and Management
- Weed Control and Herbicide Applications
- Psychedelics and Drug Studies
- Fungal Plant Pathogen Control
- Plant biochemistry and biosynthesis
- Plant and fungal interactions
- Plant and animal studies
- Natural product bioactivities and synthesis
- Mycotoxins in Agriculture and Food
- Plant Pathogenic Bacteria Studies
- Molecular spectroscopy and chirality
- Botanical Research and Chemistry
- Yeasts and Rust Fungi Studies
University of Naples Federico II
2016-2025
Regione Toscana
2023
Istituto Nazionale di Fisica Nucleare, Sezione di Napoli
2013-2022
Veterinary Oncological Center
2020-2021
World Food Programme
2017
Brigham Young University
2014-2015
University of Florence
2014
In recent decades, intensive crop management has involved excessive use of pesticides or fertilizers, compromising environmental integrity and public health. Accordingly, there been worldwide pressure to find an eco-friendly safe strategy ensure agricultural productivity. Among alternative approaches, Plant Growth-Promoting (PGP) rhizobacteria are receiving increasing attention as suitable biocontrol agents against pests. the present study, 22 spore-forming bacteria were selected among a...
An endophytic fungus isolated from healthy leaf tissues of Houttuynia cordata Thunb., an ethnomedicinal plant North East India, showed a considerable amount antimicrobial activity. The ethyl acetate extract the fungal culture filtrates displayed promising activity against panel clinically significant pathogens including Candida albicans, Staphylococcus aureus , Escherichia coli and Pseudomonas aeruginosa . Bioassay guided purification organic using column thin layer chromatography yielded...
The phytotoxicities of a selection eudesmanolides and guaianolides, including natural products new derivatives obtained by semisynthesis from plant-isolated sesquiterpene lactones, were evaluated in bioassays against three weeds concern agriculture (Amaranthus viridis L., Echinochloa crus-galli Lolium perenne L.). Both guaianolides active the root shoot growth all species, with generally showing improved activities. IC50 values for herbicide employed as positive control (on growth,...
Dengue fever, caused by dengue virus (DENV), is the most prevalent arthropod-borne viral disease and endemic in many tropical subtropical parts of world, with an increasing incidence temperate regions. The closely related flavivirus Zika (ZIKV) can be transmitted vertically utero causes congenital syndrome other birth defects. In adults, ZIKV associated Guillain-Barré syndrome. There are no approved antiviral therapies against either virus. Effective compounds urgently needed. Amaryllidaceae...
According to the current scientific paradigm, what we call 'life', 'mind', and 'consciousness' are considered epiphenomenal occurrences, or emergent properties functions of matter energy. Science does not associate these with an inherent distinct existence beyond a materialistic/energetic conception. 'Life' is word pointing at cellular multicellular processes forming organisms capable specific skills. 'Mind' cognitive ability emerging from matrix complex interactions neuronal processes,...
The plant Centaurea cineraria L. subsp. has been investigated as a potential source of inhibitors broomrape radicle growth. latter are weeds that pose threat to agriculture and for which there few methods available the control infestations. Four sesquiterpene lactones have isolated from C. aerial parts identified isocnicin, cnicin, salonitenolide, 11β,13-dihydrosalonitenolide using spectroscopic, spectrometric, optical methods. Salonitenolide first time this plant. Tested at 1.0–0.1 mM...
Pseudomonas chlororaphis subsp. aureofaciens strain M71 produced two phenazine compounds as main secondary metabolites. These metabolites were identified phenazine-1-carboxylic acid (PCA) and 2-hydroxyphenazine (2-OH P). In this study, the spectrum of activity PCA 2-OH P was evaluated against a group crop forestal plant pathogenic fungi by an agar plate bioassay. active most tested pathogens, while slightly inhibited few fungal species. Furthermore, four semisynthesised derivatives...
Two new diterpenoid α-pyrones, named higginsianins A (1) and B (2), were isolated from the mycelium of fungus Colletotrichum higginsianum grown in liquid culture. They characterized as 3-[5a,9b-dimethyl-7-methylene-2-(2-methylpropenyl)dodecahydronaphtho[2,1-b]furan-6-ylmethyl]-4-hydroxy-5,6-dimethylpyran-2-one 4-hydroxy-3-[6-hydroxy-5,8a-dimethyl-2-methylene-5-(4-methylpent-3-enyl)decahydronaphthalen-1-ylmethyl]-5,6-dimethylpyran-2-one, respectively, by using NMR, HRESIMS, chemical methods....
A new tetrasubstituted pyran-2-one and a dihydrobenzofuran, named colletochlorins E F (1 2, respectively), were isolated from the culture filtrates of fungus Colletotrichum higginsianum together with already known colletochlorin A, 4-chloroorcinol, colletopyrone. Colletochlorin E, main metabolite, characterized by spectroscopic (NMR, HRESIMS) chemical methods as 3-[7-chloro-4-hydroxy-2-(1-hydroxy-1-methylethyl)-6-methyl-2,3-dihydrobenzofuran-5-ylmethyl]-4-hydroxy-5,6-dimethylpyran-2-one...
Phytotoxic metabolites produced in liquid culture by six species of Lasiodiplodia isolated Brazil and causing Botryosphaeria dieback grapevine were chemically identified. As ascertained LC/MS, L. brasiliense, crassispora, jatrophicola, pseudotheobromae jasmonic acid, brasiliense synthesized, besides also (3R,4S)-4-hydroxymellein. euphorbicola hormozganensis some low molecular weight lipophilic toxins. Specifically, (-)-mellein, (3R,4R)-(-)- (3R,4S)-(-)-4-hydroxymellein, tyrosol, synthesized...