A5073995115- Air Quality and Health Impacts
- Carcinogens and Genotoxicity Assessment
- Heavy Metal Exposure and Toxicity
- Toxic Organic Pollutants Impact
- Indoor Air Quality and Microbial Exposure
- Climate Change and Health Impacts
- Effects and risks of endocrine disrupting chemicals
- Heavy metals in environment
- Antibiotics Pharmacokinetics and Efficacy
- Pesticide Exposure and Toxicity
- Paraquat toxicity studies and treatments
- Antioxidant Activity and Oxidative Stress
- Energy and Environment Impacts
- Vitamin C and Antioxidants Research
- Noise Effects and Management
- Colorectal Cancer Treatments and Studies
- Acute Myocardial Infarction Research
- Selenium in Biological Systems
- Advanced Glycation End Products research
- Arsenic contamination and mitigation
- Moringa oleifera research and applications
- Biosimilars and Bioanalytical Methods
- Trace Elements in Health
- Analytical Methods in Pharmaceuticals
- Pneumonia and Respiratory Infections
Universidade Federal de Santa Maria
2007-2025
Universidade Federal do Rio Grande do Sul
2010-2019
Universidade Federal do Rio Grande
2015
Pharmaceutical Biotechnology (Czechia)
2015
In-Q-Tel
2015
Objective . Cognitive impairment reduces quality of life and is related to vascular neurodegenerative disorders. However, there also a close relationship between these diseases oxidative stress. Thus, the purpose this study was assess whether inflammation damage are associated with low cognitive performance in elderly different housing conditions. Methods The groups consisted 32 institutionalized 25 noninstitutionalized Brazilian subjects. Oxidative damage, markers, function were evaluated....
Toluene is an organic solvent used in numerous processes and products, including industrial paints. neurotoxicity reproductive toxicity are well recognized; however, its genotoxicity still under discussion, toluene not classified as a carcinogenic solvent. Using the comet assay micronucleus test for detection of possible genotoxic effects toluene, we monitored painters from Rio Grande do Sul, Brazil. The putative involvement oxidative stress genetic damage influences age, smoking, alcohol...
Abstract: Caenorhabditis elegans is an alternative in vivo model that being successfully used to assess the pharmacological and toxic effects of drugs. The exponential growth nanotechnology requires use models theses nanomaterials. polymeric nanocapsules has shown promising results for drug delivery. Moreover, these formulations have not been cases intoxication, such as treatment paraquat (PQ) poisoning. Thus, drugs with properties improved by a approach overcome PQ. This research aimed...
Abstract Background We sought to investigate the relationships among plasma levels of carotenoids, tocopherols, endogenous antioxidants, oxidative damage and lipid profiles their possible effects on cardiovascular risk associated with hemodialysis (HD) patients. Methods The study groups were divided into HD healthy subjects. Plasma carotenoid, tocopherol malondialdehyde (MDA) levels, as well erythrocyte reduced glutathione (GSH), measured by HPLC. Blood antioxidant enzymes, kidney function...
N-acetylcysteine (NAC) is a potent mucolitic agent and also an antioxidant. Its antioxidant action due to its ability stimulate reduced glutathione (GSH) synthesis, therefore maintaining intracellular levels. The aim of this study was evaluate the effects NAC administered intraperitoneally (i.p.) in decreasing oxidative tissue damage liver kidney alloxan-induced diabetic rats, especially on thiolic groups (nonproteic proteic groups). Adult male Wistar rats (200–350 g) were used; diabetes...
The use and marketing of herbicides are increasing worldwide. Glyphosate 2,4 dichlorophenoxyacetic acid (2,4D) the most prominent in this progression, used alone combination. There few reports on effects these Caenorhabditis elegans (C. elegans) experimental model has a complete system is easy to manipulate maintain. This study evaluated toxicity glyphosate 2,4D combination with parameters survival, development, reproduction C. at 4 different concentrations (0.115-0.925 mg/mL for from 1.046...
Children’s exposure to metals can result in adverse effects such as cognitive function impairments. This study aimed evaluate some toxic and levels of essential trace elements blood, hair, drinking water children from a rural area Southern Brazil. Cognitive ability δ-aminolevulinate dehydratase (ALA-D) activity were evaluated. Oxidative stress was evaluated main mechanism metal toxicity, through the quantification malondialdehyde (MDA) levels. included 20 an urban area. Our findings...