A5071789715- Autism Spectrum Disorder Research
- Dementia and Cognitive Impairment Research
- Attention Deficit Hyperactivity Disorder
- Genetics and Neurodevelopmental Disorders
- Family and Disability Support Research
- Behavioral and Psychological Studies
- Primary Care and Health Outcomes
- COVID-19 and healthcare impacts
- Personality Disorders and Psychopathology
- Blood Coagulation and Thrombosis Mechanisms
- Diversity and Career in Medicine
- Pharmacy and Medical Practices
- Biofuel production and bioconversion
- Asthma and respiratory diseases
- Healthcare professionals’ stress and burnout
- Youth Substance Use and School Attendance
- Animal testing and alternatives
- Medication Adherence and Compliance
- Colorectal Cancer Screening and Detection
- Patient Satisfaction in Healthcare
- Hospital Admissions and Outcomes
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Hemophilia Treatment and Research
- Enzyme Catalysis and Immobilization
- Cell Image Analysis Techniques
Royal Brisbane and Women's Hospital
2024
Gold Coast Health
2021-2024
South London and Maudsley NHS Foundation Trust
2009-2024
Gold Coast Hospital
2018-2024
King's College London
2010-2022
UNSW Sydney
2021
Trinity College Dublin
2021
St. James's Hospital
2021
Memorial University of Newfoundland
2020
Griffith University
2018
Background High rates of anxiety disorders, particularly obsessive compulsive disorder (OCD) are reported in people with Autism spectrum disorders (ASD). Group cognitive behavioral treatment (CBT) has been found effective for young ASD but not OCD specific. One uncontrolled pilot study individual CBT adults showed good efficacy. Methods Forty-six adolescents and (mean age 26.9 years, 35 Males) comorbid were randomized to or management (AM), a plausible control treatment. Treatments matched...
Growing awareness of autism spectrum disorders has increased the demand for diagnostic services in adulthood. High rates mental health problems have been reported young people and adults with disorder. However, sampling methodological issues mean prevalence estimates conclusions about specificity psychiatric co-morbidity disorder remain unclear. A retrospective case review 859 referred assessment compares International Classification Diseases, Tenth Revision diagnoses those that met criteria...
Real‐life social processing abilities of adults with autism spectrum disorders (ASD) can be hard to capture in lab‐based experimental tasks. A novel measure cognition, the “Strange Stories Film task’ (SSFt), was designed overcome limitations available measures field. Brief films were made based on scenarios from Strange task (Happé) and subtle social‐cognitive difficulties observed ASD adults. Twenty neurotypical recruited pilot new measure. final test set produced administered a group 20...
Studies of executive function (EF) in autism spectrum disorder (ASD) have reported mixed findings. Possible confounds include EF domain assessed and co-occurring neurodevelopmental diagnoses. task performance across multiple domains everyday autistic adults (n = 110) was significantly different to age- IQ-matched controls 31). Although more likely fall into the clinically impaired range, 35.8% ASD group showed no impairment on measures. Factor analysis revealed a single unifying construct...
There are very few case series of patients with acute psychogenic memory loss (also known as dissociative/functional amnesia), and still fewer studies outcome, or comparisons neurological memory-disordered patients. Consequently, the literature on amnesia is somewhat fragmented offers little prognostic value for individual In present study, we reviewed records neuropsychological findings in 53 cases (ratio 3:1, males:females), comparison 21 consecutively recruited 14 healthy control...
Abstract Objective To gain insight into caregivers' understanding of the causes behaviours they find problematic in people with Alzheimer's disease order to inform development educational strategies. Methods A qualitative, semi‐structured interview was used. Participants were 205 caregivers for a person disease, all whom aware diagnosis and who had been recruited as part larger longitudinal study. from inner‐city suburban London/semi‐rural Essex. The main outcome measures of: cause...
Features of attention deficit hyperactivity disorder (ADHD) and impairments on neuropsychological, tests have been documented in children with autism spectrum disorders (ASDs). To date, there has a lack research comparing adults ASD ADHD. In study 1, 31 average intellectual function completed self-report measures ADHD symptoms. These were compared symptoms 38 29 general population controls. 2, 28 diagnosis an age- intelligence quotient-matched sample across range attention. Study 1 showed...
Effective participation in trial is outlined under article 6 of the European Convention on Human Rights and refers to ability understand engage trial. Juvenile defendants are often referred psychologists or psychiatrists by their solicitors establish 'effective participation' capacity. In USA, key components participate effectively defined standardised assessments available. UK, no formal measures exist. A consecutive series 20 adolescents aged 12–20 years, our service, were assessed using a...
Calcium waves represent a widespread form of intercellular communication. Although they have been thought for long time to require gap junctions, we recently demonstrated that mouse cortical astrocytes use an extracellular messenger calcium wave propagation. The present experiments identify ATP as major in this system. Medium collected from astrocyte cultures during (but not before) stimulation contains ATP. excitatory effects medium samples and are blocked by purinergic receptor antagonists...
Background and objectiveTransition from hospital to community care is well established as a high-risk time for patients.Inadequate clinical handover general practice puts patients at risk of medical error, adverse events rehospitalisation.We sought understand the effects on practitioners (GPs) poor inpatient, outpatient emergency department settings. MethodsQualitative methodology was used through conducting semi-structured interviews with purposively selected GPs.Interviews were undertaken...
Background The screening test usually used to detect dementia (Mini Mental State Examination, MMSE) is limited by a ceiling effect and high false positive rates, as are other similar instruments. There therefore need for more sensitive specific tool aid early detection diagnosis of dementia. Objective hypothesis the study was that TE4D-Cog would be than MMSE in detecting mild cognitive impairment patients with AD. Method TE4D (Test Early Detection Dementia from Depression) adapted its...
Junior doctors face uncertain career progression and futures as a consequence of the pandemic Frontline health care workers have been central to coronavirus disease 2019 (COVID-19) response. For most individuals in medical profession, this required an adjustment new way working established career, but for junior it emerged very early formative days their career. The implications may significant consequences doctors, particular, disruption progression. first Australian case COVID-19 January...
This paper considers current workforce issues facing psychological professionals working in NHS services, examining the challenges, and identifying opportunities to better meet needs of autistic people with an intellectual disability (PwID) across lifespan. The aim this is identify publicly articulate need for a coherent approach guide practice when helping and/or PwID. It should be noted that scope limited autism disability. In addressing these broad groups their co-occurring conditions...
Background: When a patient is discharged from hospital it essential that their general practitioner (GPs) and community pharmacist are informed of changes to medicines. This necessitates effective communication information-sharing between hospitals primary care clinicians. Objective: To identify priority medicine handover issues solutions inform the co-design development multifaceted intervention. Method: A modified nominal group technique was used reach consensus on areas. The first hour an...
Children excluded from school often have a range of unidentified needs that may directly contribute to their behaviour. Research and policy highlight the absence screening for difficulties in children at risk exclusion. This study aimed assess explore feasibility acceptability neurodevelopmental mental health secondary with two or more fixed-term exclusions, as well compare differences rates matched controls. Mental measures were collected 40 aged 11–16, 13 parents 9 teachers. The process...
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This study evaluated the impact of a daily relaxation group on levels challenging behaviour presented by adults with diagnosis high functioning autism at specialist assessment and treatment unit.