A5102535461- Nanoparticle-Based Drug Delivery
- Random lasers and scattering media
- Nanoplatforms for cancer theranostics
- Advanced Optical Imaging Technologies
- RNA Interference and Gene Delivery
- Dendrimers and Hyperbranched Polymers
- Catalytic Processes in Materials Science
- Advanced Optical Sensing Technologies
- Computer Graphics and Visualization Techniques
- Advanced Polymer Synthesis and Characterization
- Photodynamic Therapy Research Studies
- Neural Networks and Reservoir Computing
- Graphene and Nanomaterials Applications
- Advanced Drug Delivery Systems
- Advanced MIMO Systems Optimization
- Advanced Wireless Network Optimization
- Advanced Glycation End Products research
- Supramolecular Chemistry and Complexes
- Electrocatalysts for Energy Conversion
- Bone Tissue Engineering Materials
- Oral microbiology and periodontitis research
- Supramolecular Self-Assembly in Materials
- Information and Cyber Security
- Semiconductor materials and devices
- Organoselenium and organotellurium chemistry
State Key Laboratory of Respiratory Disease
2025
Target (United States)
2025
Guangzhou Medical University
2025
Sichuan University
2011-2024
West China Hospital of Sichuan University
2024
Chengdu University of Traditional Chinese Medicine
2024
Southwest Medical University
2024
Beijing University of Posts and Telecommunications
2014-2024
Tongji Hospital
2021
Huazhong University of Science and Technology
2021
Polymeric nanoparticles generated by mPEG-tetrakis(4-carboxyphenyl)porphyrin amphiphiles were used to trap doxorubicin for synergistic chemo-photodynamic therapy.
A green, efficient, and environmentally friendly electrochemical strategy was developed for synthesizing a series of selenoheterocyclic compounds. The antitumor activities these compounds were evaluated, revealing that 4o, 5n, 5o demonstrated remarkable efficacy. These effectively inhibited lung cancer by inducing cell apoptosis, causing DNA damage, suppressing the progression epithelial-mesenchymal transition. Notably, compound identified as first inhibitor DEAD-box helicase 10 (DDX10). An...
Rietveld refinement is used to investigate the crystal structure of prepared (0.965 – x)(K0.48Na0.52)NbO3–xBiInO3–0.035(Bi0.5Na0.5)ZrO3 (KNN-xBI-BNZ) ceramics. From refined results, distortion degree structures in KNN-xBI-BNZ ceramics presents a rising trend with BiInO3 modification, which keeping results diffuseness. The spontaneous polarization (Ps) also calculated using structural parameters. submicron domains are observed when x = 0.004, good electrical properties (d33 317 pC/N, Tc 336...
In this paper, a novel micelle for anti-tumor drug delivery was reported. Two 7-carboxymethoxy coumarin molecules were immobilized on the terminal group of methoxy poly(ethylene glycol) chain via l-lysine as linker. The amphiphilic monoend-functionalized (mPEG-Lys-DCOU) chains self-assembled micelles. Anti-tumor doxorubicin loaded in mPEG-Lys-DCOU micelles and release profile studied. cytotoxicity evaluated by NIH 3T3 fibroblasts. drug-loaded incubated with HepG2 tumor cells to investigate...
The chain length effect of chrysin modified mPEG–PCL micelles with exciting doxorubicin loading capacity on drug delivery was investigated.
Hot-melt extrusion (HME) plays an important role in preparing implants as local drug delivery systems pharmaceutical fields. Here, a new PLA/PEG-PPG-PEG/Dexamethasone (PLA/F68/Dex) implant prepared by HME has been developed. Importantly, the was successfully achieved to control release of immunosuppressive implanted device. In particular, this not reported previously FTIR and XRD were adopted investigate properties samples. The vivo study showed that maximum value Dex from approximately 50%...
Fisetin (3,3',4',7-tetrahydroxyflavone) is a potential anti-tumor agent but poor water solubility hinders its application and complicates direct parenteral administration. Nanoparticle encapsulation an efficient way to enhance the of some hydrophobic drugs. In this study, methoxy poly(ethylene glycol)-polycaprolactone (MPEG-PCL) nanoparticles were successfully prepared for fisetin delivery in vitro vivo. Narrow distribution fisetin-loaded MPEG-PCL NPs (aproximately100 nm) obtained via...
In recent years, the self-assembly polymeric nanoparticles are widely used for anti-tumor drug delivery. Multiple interactions such as hydrogen bonding, host-guest interaction, hydrophobic interaction and electrostatic have been utilized to generate nanoparticles. Herein, a new amphiphile with methoxy poly(ethylene glycol) (mPEG) hydrophilic block pi-pi conjugated small molecule N-(9-Fluorenylmethoxycarbonyl)-L-phenylalanines (Fmoc-Phe-OH) instead of polymer chain lipophilic segment was...
In this paper, we successfully synthesized amino-terminated poly(ethylene glycol)-block-poly (epsilon-caprolactone) (NH2-PEG-PCL) block copolymer from polyethylene glycol 2000, epsilon-caprolactone (epsilon-CL) and hydrazine hydrate. The obtained was characterized by nuclear magnetic resonance (1H-NMR), the molecular weight distribution of NH2-PEG-PCL were Gel permeation chromatography (GPC). could self-assemble into micelles in water. Paclitaxel (PTX) loaded (PNPP) prepared solid dispersion...
Nowadays, Voice of LTE (VoLTE) is used to support voice communications in network. As one the key techniques for VoLTE, semi-persistent scheduling (SPS) important improve capacity VoLTE users. However with SPS, resource and modulation coding scheme (MCS) are usually decided by initial keep unchanged during active state. Considering continuously changing channel, it hard ensure performance packet. In order solve this problem, a allocation algorithm proposed based on prediction channel quality...
Water electrolysis is an environmentally friendly and sustainable hydrogen production method. The proper design of the catalyst surface essential for oxygen evolution reaction (OER) in water process because catalytic effect highly dependent on contact properties such as homogeneity coating stability catalyst, well wettability electrolyte. Herein, hydrogel [consisting poly(vinyl alcohol) (PVA) cross-linked with quaternized chitosan (HACC)] loaded nickel foam (NF) was chosen to study OER iron...
Improving the quality of wavefront shaping (WFS) is a major problem anti-scattering optical information transmission in perturbation environment. To tackle this issue, we propose simple and robust method, named Point Guard algorithm (PGA), to manipulate interference by encoding digital micromirror device (DMD). The PGA method inspired movement strategies (PG) professional basketball association. Compared with most popular genetic (GA), proposed has stronger anti-perturbation capacity. In...
Xin Yu Denga, Wei Tao Xua, Ming Liua, Mei Xiang Yanga, Qian Jiang Zhua, Bin Lü*a & Zhu Tao*aa Key Laboratory of Macrocyclic and Supramolecular Chemistry Guizhou Province, University, Guiyang, The People’s Republic China
CSI-RS (Channel State Information Reference Signal) is designed for higher-order MIMO in LTE-A. However, it could be problematic LTE legacy UEs a LTE-A network deployed because cannot distinguish from effectual data. In this paper, the impact of on are firstly evaluated by both link-level and system-level simulations. The evaluation results show that degradation UEs' performance caused obvious when coding rate modulation scheme too large. To reduce degradation, two mechanisms, named SLA...
The modification of Ir or oxygen vacancies (Vo) is a strategy to enhance the evolution reaction (OER) performance heterogeneous nanocatalysts. However, it crucial further clarify synergistic effect and Vo on enhancement mechanism OER after surface reconstruction. In this work, FeCo Layered double hydroxides (LDHs) co-modified by were successfully prepared thermodynamically favorable galvanic replacement reaction. Electrochemical impedance spectroscopy confirmed that enhanced charge transfer...
Abstract Background: This study aims to investigate the influence of two oral mouthwash interventions on microbiome HNC patients at multiple time points, while simultaneously assessing their prognostic significance. Additionally, it seeks identify distinctive biomarkers that are linked different subtypes HNC. Methods: Patients with were subjected random allocation into distinct intervention groups: normal saline group denoted as N and yikou gargle employing chlorhexidine, represented Y....