A5006982215- Parasites and Host Interactions
- IL-33, ST2, and ILC Pathways
- Parasite Biology and Host Interactions
- Organometallic Complex Synthesis and Catalysis
- Parasitic Diseases Research and Treatment
- Helminth infection and control
- Reproductive System and Pregnancy
- Eosinophilic Esophagitis
- Lanthanide and Transition Metal Complexes
- Parasitic Infections and Diagnostics
- Asthma and respiratory diseases
- Metal complexes synthesis and properties
- Zoonotic diseases and public health
Centre National de la Recherche Scientifique
2024
Université Grenoble Alpes
2024
CEA Grenoble
2024
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2024
Laboratoire de Chimie et Biologie des Métaux
2024
University of Glasgow
2020-2023
Wellcome Centre for Molecular Parasitology
2020-2023
Type 2-high asthma is a chronic inflammatory disease of the airways which increasingly prevalent in countries where helminth parasite infections are rare, and characterized by T helper 2 (Th2)-dependent accumulation eosinophils lungs. Regulatory cytokines such as TGF-β can restrain reactions, dampen allergic Th2 responses, control eosinophil activation. The murine Heligmosomoides polygyrus releases mimic (Hp-TGM) that replicates biological functional properties despite bearing no structural...
Light‐driven electron transfer and subsequent multielectron storage is among the key aspects of photochemical reactions in artificial photosynthesis molecular electronics. Following our previously introduced design characterization Ru(II)‐based photosensitizers, four new Ru complexes with π‐extended ligands featuring a flavin‐inspired subunit were investigated via density functional theory order to evaluate their electrochemical properties ahead time resource demanding synthesis. Two...
Inflammatory bowel disease (IBD) is a set of immunological disorders which can generate chronic pain and fatigue associated with the inflammatory symptoms. The treatment IBD remains significant hurdle current therapies being only partially effective or having side effects, suggesting that new elicit different modes action delivery strategies are required. TGM1 TGF-β mimic was discovered from intestinal helminth parasite Heligmosomoides polygyrus thought to be produced by suppress...
Abstract Molecular charge accumulating systems that act as both, photosensitizer and electron storage unit, are of interest in the context multielectron redox processes, e. g. solar fuel production. To this end, photophysical properties RuL1 , a ruthenium tris‐diimine complex with an alloxazine‐based ligand bioinspired structural motif, were investigated. The study includes absorption, emission, resonance Raman transient absorption spectroscopy combination quantum chemical simulations to...