- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Reproductive Health and Contraception
- Genital Health and Disease
- Systemic Sclerosis and Related Diseases
- Female Genital Mutilation/Cutting Issues
- Salivary Gland Disorders and Functions
- Reproductive Health and Technologies
- Spondyloarthritis Studies and Treatments
- Inflammatory mediators and NSAID effects
- Proteoglycans and glycosaminoglycans research
- Reproductive tract infections research
- Urticaria and Related Conditions
- Sexual function and dysfunction studies
- Monoclonal and Polyclonal Antibodies Research
- Autoimmune and Inflammatory Disorders Research
- Cell Adhesion Molecules Research
- Osteoarthritis Treatment and Mechanisms
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Bone health and treatments
- Adolescent Sexual and Reproductive Health
- Ectopic Pregnancy Diagnosis and Management
- Musculoskeletal synovial abnormalities and treatments
- Inflammatory Myopathies and Dermatomyositis
- Psoriasis: Treatment and Pathogenesis
University Hospital of Geneva
2014-2025
Geneva College
2023-2025
Hôpital Beau-Séjour
2018-2023
University of Geneva
2006-2023
Service de Santé de la Jeunesse
2018-2020
University of Lausanne
2020
Bnai Zion Medical Center
2020
Maccabi Health Care Services
2020
University of Zurich
2017
The Medical Center of Aurora
2011
Forty-nine Israeli Jewish patients with rheumatoid arthritis (RA) were studied for their HLA A, B, C, DR antigen frequency. A significant increase in Aw31 and DR1 was observed (p less than 5.10(-5) p 5.10(-3) respectively). 45% of positive sero-negative factor, while most individuals seropositive. DR5 found to be significantly decreased 5.10(-4)). Contrary previous reports, DRw4 within the range frequency controls (34.7% vs. 32%). It is suggested that our population not DR4 are highly...
Aspirin is known to have a bimodal effect on the renal handling of uric acid (UA). High dosages (>3 gm/day) are uricosuric, while low (1-2 cause UA retention. Although very-low-dose (mini-dose) aspirin used increasingly as platelet aggregation inhibitor, no studies been published whether aspirin's effects occur at <0.5 gm/day. The aim present study was evaluate commonly mini-dosages function and in elderly patients.The included 49 inpatients (age 61-94). Patients were excluded if they had...
<h3>OBJECTIVE</h3> To evaluate the effect of hydroxychloroquine treatment on interleukin 6 (IL6), hyaluronic acid (HA), and soluble 2 receptor (sIL2R) concentrations in saliva serum patients with primary Sjögren's syndrome (SS). <h3>METHODS</h3> Fourteen SS treated 200 mg/day for 12 months were investigated an open prospective study. Clinical parameters efficacy routine biochemical haematological data to assess drug safety tolerability determined every three months. Salivary IL6, sIL2R, HA...
The Chicago consensus statement of 2005 was created at the point cumulative criticisms and debates around clinical practice childhood genital surgery. It drawn up a time when it had become clearer that medically non-essential paediatric operations were associated with poor adult cosmetic outcomes sexual functioning. However, data not available for non-intervention. Therefore, parents clinicians no reliable information on how child growing atypical genitalia might fare. most positive...
OBJECTIVE: To describe a novel iatrogenic immunological reaction produced by minocycline. CASE REPORTS: The clinical course and laboratory results of three women who presented with similar rheumatological manifestations after prolonged exposure to minocycline are described. All unique manifested fever, arthritis/arthralgia livedo reticularis during treatment for acne vulgaris. syndrome was associated high titre serum perinuclear anticytoplasmatic antibodies (p-ANCA) antimyeloperoxidase...
745 Background: In a Phase 2 trial, treatment of non-resectable locally advanced pancreatic cancer (LAPC) patients harboring the KRAS G12D or G12V mutations, with SiG12DLoder combined chemotherapy resulted in superior median overall survival (OS) 9.3 months over (not statistically significant) and Objective Response Rate 55% (35% control), when administered once every 3 (Clinical trial # NCT01676259, ESMO 2023, abstract FPN: 1626). SIL-204 which is modified version siRNA siG12D composed...
Abstract Vulvar Lichen Sclerosus(VLS) is an uncommon, often misdiagnosed condition with a chronic course. Children presenting VLS may have wide variety of complaints, which complicates diagnosis. The differentiation symptoms in the course causes great diagnostic difficulties. Delayed diagnosis impact on vulvar architecture and long-term sexual health, can lead to frustration for both patient her parents. aim this study was determine reasons delayed girls adolescents investigate number...
<title>Abstract</title> Pregnancy constitutes an at-risk factor for severe COVID-19. Several clinical studies have previously suggested increased risks of adverse obstetrical outcomes and placental pathological changes in pregnant women infected with SARS-CoV-2. In this study, our goal was to assess the susceptibility trophoblast SARS-CoV-2 infection at early stage pregnancy its impact on cell fusion <italic>in vitro</italic>. We showed that first trimester cytotrophoblast (CTB)...