Hossein Aghazadeh

ORCID: 0000-0003-0681-071X
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About
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Research Areas
  • Antimicrobial Peptides and Activities
  • Biochemical and Structural Characterization
  • Viral Infectious Diseases and Gene Expression in Insects
  • RNA Interference and Gene Delivery
  • Bee Products Chemical Analysis
  • Insect and Pesticide Research
  • Monoclonal and Polyclonal Antibodies Research
  • Lipid Membrane Structure and Behavior
  • CAR-T cell therapy research
  • vaccines and immunoinformatics approaches
  • Aquaculture disease management and microbiota
  • Protein purification and stability
  • Invertebrate Immune Response Mechanisms

Biotechnology Research Center
2018-2022

Islamic Azad University, Ashkezar
2020

Islamic Azad University, Yazd
2020

Pasteur Institute of Iran
2018-2019

Abstract Human cathelicidin LL‐37 has recently attracted interest as a potential therapeutic agent, mostly because of its ability to kill wide variety pathogens and cancer cells. In this study, we aimed investigate the antibacterial activity cytotoxicity previously designed anticancer derivatives (i.e., P7, P22, P38). Calcein release assay field emission‐scanning electron microscopy (FE‐SEM) were performed elucidate possible mechanism action P38, peptide with highest bactericidal activity....

10.1111/cbdd.13381 article EN Chemical Biology & Drug Design 2018-08-18

Chinese hamster ovary cells are the main cellular factories for production of wide range recombinant proteins in biopharma industry. Recombinant human Interferon beta-1a (rh-IFN β-1a), as a cytokine is widely used to treat multiple sclerosis. In this work, rh-IFN β-1a was studied improve cell density along with specific expression. To achieve that, first step culture experiments were done using commercial serum-free media find optimal one providing higher density. It shown DMEMF12,...

10.2139/ssrn.4001203 article EN SSRN Electronic Journal 2022-01-01
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