A5066440332- Nutrition, Genetics, and Disease
- Health Systems, Economic Evaluations, Quality of Life
- BRCA gene mutations in cancer
- Genomics and Rare Diseases
- Ethics in Clinical Research
- Health, Environment, Cognitive Aging
- Pharmaceutical Economics and Policy
- Biotechnology and Related Fields
- Health and Medical Studies
- Genetics, Bioinformatics, and Biomedical Research
- Biomedical and Engineering Education
- Healthcare cost, quality, practices
- Gut microbiota and health
- Child and Adolescent Health
- Law and Political Science
- Cancer Genomics and Diagnostics
- Intellectual Property and Patents
- Science, Research, and Medicine
- Biomedical Ethics and Regulation
- Reproductive tract infections research
- Global Public Health Policies and Epidemiology
- Biosimilars and Bioanalytical Methods
- Vaccine Coverage and Hesitancy
- Health Literacy and Information Accessibility
- Legal, Health, Environmental and COVID-19 Challenges
United Nations University – Maastricht Economic and Social Research Institute on Innovation and Technology
2016-2025
Maastricht University
2016-2025
Manipal Academy of Higher Education
2017-2024
Virginia Commonwealth University
2018-2023
Deutsches Zentrum für Luft- und Raumfahrt e. V. (DLR)
2015
Institute of Genetics
2015
Norwegian Directorate of Health
2015
Breast Cancer Research Foundation
2015
Queen's University Belfast
2015
Institute of Public Health Zadar
2013-2014
This article is part of a Focus Theme Methods Information in Medicine on Health Record Banking.Healthcare often ineffective and costs are steadily rising. large due to the inaccessibility medical health data stored multiple silos. Furthermore, most cases molecular differences between individuals that result different susceptibilities drugs diseases as well targeted interventions cannot be taken into account. Technological advances genome sequencing interaction 'omics' with environmental one...
<b><i>Background:</i></b> Personalised medicine (PM) is an innovative way to produce better patient outcomes by using individualised or stratified approach disease and treatment rather than a collective for patients. Despite its tangible advantages, the complex process translate PM into member states European healthcare systems has delayed uptake. The aim of this study identify relevant barriers represented index summarise challenging areas implementation in Europe....
So far health literacy has not been sufficiently discussed in the context of public genomics. Primarily, genomic but rather genome-based information needs to be addressed taking into account genome-environment interactions and integrating all determinants including genomics a systemic holistic approach. Translating findings from epigenomics systems biomedicine will help understand that individual biological pathways or networks are permanently interacting with environmental such as social...
Over the last decade European Union has been coordinating actions addressing various aspects of rare diseases and funded several cross-border research projects. Recently initiated biggest disease international collaborative effort by launching International Rare Diseases Research Consortium (IRDiRC). RARE-Bestpractices is one more than 100 projects on under Seventh Framework Programme for Technological Development (FP7; 2007-2013) (1). As a wide, open inclusive network, will build knowledge...
In recent years, the translation of genomic discoveries into mainstream medical practice and public health has gained momentum, facilitated by advent new technologies. However, there are often major discrepancies in pace implementation medicine between developed developing/resource-limited countries. The main reason does not only lie limitation resources but also slow adoption findings poor understanding potential that this discipline offers to rationalize diagnosis treatment. Here, we...
ABSTRACT The use of data analytics across the entire healthcare value chain, from drug discovery and development through epidemiology to informed clinical decision for patients or policy making public health, has seen an explosion in recent years. increase quantity variety available together with improvement storing capabilities analytical tools offer numerous possibilities all stakeholders (manufacturers, regulators, payers, providers, makers, researchers) but most importantly, it potential...
Abstract Background Oral diseases affect close to 3.5 billion people worldwide and there has been a call by the World Health Organization (WHO) integrate oral health into Universal Coverage (UHC) agenda. Objectives To collate synthesise information regarding status of integration systems covered UHC across 11 countries in South East Asian Regional Office. Methods Drawing on framework six building blocks as devised WHO, we compared public dental care coverage models, with focus outpatient...
The sharing of samples and data stored in biobanks for research has implications donor privacy, but also raises questions on the regulation within Europe. Many legal documents principles Europe, with a direct impact biobanking, have not been developed specifically to support this activity. Moreover, while some new regulations set up at national level, there are many variations definitions, scope purpose these instruments. This resulted unnecessary hurdles genome-based research, particularly...
Objective: To assess the willingness of older Swiss adults to share genetic data for research purposes and investigate factors that might impact their data. Methods: Semi-structured interviews were conducted among 40 participants (19 male 21 female) aged between 67 92 years, December 2013 April 2014 attending Seniorenuniversität Zürich, Switzerland. All audio-recorded, transcribed verbatim, anonymized. For analysis interviews, an initial coding scheme was developed, refined over time,...
<b><i>Introduction:</i></b> Currently, abundances of highly relevant health data are locked up in silos due to decentralized storage and protection laws. The cooperative (HDC) model is established make this valuable available for societal purposes. aim study analyse the HDC its potentials challenges. <b><i>Results:</i></b> An a bank. has as core principles approach, citizen-centredness, not-for-profit structure, enquiry procedure, worldwide...
National and international medicines agencies have developed innovative methods to expedite promising new the market facilitate early patient access. Some of these approval pathways are conditional adaptive by European Medicines Agency (EMA); Promising Innovative Medicine (PIM) designation Early Access Scheme (EAMS) Healthcare Products Regulatory (MHRA), as well Fast Track, Breakthrough or Accelerated Approval Food Drug Administration (FDA). However, at least in Europe, cannot achieve goal...
Background: An increasing number of medicines authorised in Europe recommend or require biomarker-based patient selection. For some these the use a companion diagnostic (CDx), subset vitro diagnostics (IVDs), to identify populations eligible for specific medicinal product may be required. The information and recommendations which CDx is required particularly important healthcare professionals correct identification. Methods: We reviewed existing SmPCs European Public Assessment Reports...
Healthcare systems are major emitters of greenhouse gases that contribute to climate change. The resulting crisis harms human and planetary health increasingly impacts lives on Earth. Because their status as high social role in society, healthcare have a clear obligation decarbonise. This study investigates how worldwide can lower gas emissions thereby global action. We performed systematic literature review, searching PubMed, GreenFILE, Business Source Complete CINAHL for relevant empirical...
Abstract Chlamydia trachomatis (CT) remains a significant infectious cause of blindness and sexually transmitted infections worldwide. The objective novelty this study lie in using different serovars CT to design broad-spectrum multi-epitope vaccine that might confer immunity against infections. As the major outer membrane protein has good immunodominance properties high conservation also determines several serotypes CT, it is selected as an antibody target study. T-cell B-cell epitopes from...