A5101693122- Cancer-related molecular mechanisms research
- Epigenetics and DNA Methylation
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hedgehog Signaling Pathway Studies
- Cancer-related gene regulation
- Circular RNAs in diseases
- RNA modifications and cancer
- Colorectal Cancer Treatments and Studies
- Cancer Diagnosis and Treatment
- Inflammatory Biomarkers in Disease Prognosis
- Colorectal and Anal Carcinomas
- Cancer Risks and Factors
- Colorectal Cancer Surgical Treatments
- Bone health and treatments
- Cancer and Skin Lesions
- Cancer Mechanisms and Therapy
- Optical Imaging and Spectroscopy Techniques
- Immunotherapy and Immune Responses
- Infrared Thermography in Medicine
- RNA Research and Splicing
- Nanoparticle-Based Drug Delivery
- Nanoparticles: synthesis and applications
- Peptidase Inhibition and Analysis
- Blood disorders and treatments
- Chemotherapy-related skin toxicity
Huaian First People’s Hospital
2017-2022
Nanjing Medical University
2017-2022
Tianjin Medical University Cancer Institute and Hospital
2011-2021
Jiangsu Province Hospital
2018
Tianjin Medical University
2009-2010
Breast cancer is the most common malignant tumor and main cause of cancer-associated mortality in females worldwide. Long non-coding RNAs (lncRNAs) have been reported to play vital roles breast development progression; however, our understanding lncRNAs still limited. In this study, we demonstrated that small nucleolar RNA host gene 5 (SNHG5) promotes cell proliferation both vitro vivo, depletion SNHG5 significantly led cell-cycle arrest at G1 phase. Accumulating evidence has shown many...
Abstract Background N 6-Methyladenosine (m6A) is the most common RNA modification and regulates splicing, translation, translocation, stability. Aberrant expression of m6A has been reported in various types human cancers. dynamically reversibly mediated by different regulators, including methyltransferase, demethylases, binding proteins. However, role methylation regulators thyroid cancer remains unknown. The aim this study to investigate effect 13 main carcinoma. Methods We obtained...
Abstract More women are delaying child-birth. Thus, the diagnosis of pregnancy-associated breast cancer (PABC) will continue to increase. The aim this study was identify core candidate genes PABC, and relevance on prognosis PABC. GSE31192 GSE53031 microarray profile datasets were downloaded from Gene Expression Omnibus database differentially expressed analyzed using R package GEO2R tool. Then, Ontology Kyoto Encyclopedia Genome pathway enrichment analyses performed Database for Annotation,...
Purpose. To investigate the association of platelet-derived growth factors (PDGFs), clinicopathological features, and prognosis in gastric cancer patients. Methods. Tumor specimens 180 individuals with treated between 2016 2020 were collected. Immunohistochemical staining Western blot (WB) used to detect expression PDGF-B PDGF-D. The relationship PDGF-D relapse-free subsistence (RFS) time was assessed using Kaplan–Meier curves. Univariate multivariate Cox proportional hazards regression...
G protein γ subunit 7 (GNG7) is a of heterotrimeric protein. It has been demonstrated low expressed GNG7 in various cancers. Nevertheless, the role lung adenocarcinoma (LUAD) remains unclear. In present study, expression LUAD tissues and cell lines was analyzed by RT-qPCR, western blot immunohistochemical. Kaplan-Meier analysis performed for determining prognostic value expression. Then, function progression examined proliferation, invasion mouse xenograft assays. addition, underlying...