- Salivary Gland Tumors Diagnosis and Treatment
- Breast Lesions and Carcinomas
- Cancer and Skin Lesions
- Cancer Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Lymphoma Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Soft tissue tumor case studies
- Cervical Cancer and HPV Research
- Thyroid Cancer Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Cutaneous lymphoproliferative disorders research
- Viral-associated cancers and disorders
- Ear and Head Tumors
- Urinary and Genital Oncology Studies
- Oral and Maxillofacial Pathology
- Head and Neck Cancer Studies
- Vascular Tumors and Angiosarcomas
- Tumors and Oncological Cases
- Uterine Myomas and Treatments
- BRCA gene mutations in cancer
- Soft tissue tumors and treatment
- CNS Lymphoma Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Chronic Lymphocytic Leukemia Research
Memorial Sloan Kettering Cancer Center
2016-2024
Stellar Science (United States)
2019
Gynecologic Oncology Group
2016-2019
Government of the Republic of Korea
2016-2019
Spanish Oncology Genitourinary Group
2016
Mount Sinai Beth Israel
2000-2015
Pennsylvania Hospital
2009
University of Pennsylvania Health System
2009
St. Luke's-Roosevelt Hospital Center
2003-2008
Los Angeles Medical Center
2003
Background: The change in size of the papillary thyroid cancer (PTC) nodule during active surveillance has traditionally been characterized as either stable, increasing, or decreasing based on changes maximal tumor diameter volume. More recently, it observed that observation are more complex with volume kinetic patterns can be stable (Pattern I), early increase II), later III), followed by stability IV), an V), a decrease VI). Methods: frequency, time course, and clinical correlates these...
BACKGROUND The distinction of a primary lung carcinoma from metastatic lesion is important, because the treatment and prognosis differ for patients with these malignancies. Such can be difficult overlapping cytologic features. It has been shown that antibodies to thyroid transcription factor 1 (TTF-1) PE-10 are fairly specific markers tumors in histologic specimens. TTF-1 regulates expression surfactant protein production, monoclonal antibody against components human proteins. combination...
BACKGROUND Although stereotaxic fine-needle aspiration biopsy or core (14-gauge) have proven to be accurate techniques for the evaluation of mammographically detected microcalcification, development Mammotome Biopsy System (Biopsys Medical, Inc., Irvine, CA) has led many medical centers use this vacuum-assisted device sampling microcalcification. METHODS One hundred forty-two women underwent 160 biopsies mammographic calcification over a 1-year period. The procedure was performed by...
INTRODUCTION. Although the cytologic features of Hodgkin disease (HD) has been well described, HD accounts for most false-negative fine-needle aspiration (FNA) biopsies malignant lymphomas. In this study, authors examined factors contributing to a diagnosis HD.Eighty-nine cases from 72 patients (23 females and 49 males) with evaluated by FNA were identified between 1990 1999. The patients' ages ranged 5 90 years (median, 38 years). Eighty-five FNAs lymph nodes, 4 extranodal sites. Histologic...
Genomic profiling is now available for risk stratification of cytologically indeterminate thyroid nodules (ITNs). Mutations in
Abstract Background The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) provides a standardized reporting system salivary gland fine‐needle aspiration (SGFNA). We review the clinical utility of MSRSGC at tertiary care cancer center by assessing rates malignancy (ROM) among different categories. Methods A retrospective search was performed to retrieve all SGFNA cases our institution between 1/1/07 and 12/31/18. initial primary diagnoses were recorded then assigned appropriate...
Spindle cell and mesenchymal lesions of the lung encompass a wide variety benign malignant conditions. However, to authors' knowledge, because their rarity, few reports concerning cytologic findings are available in literature. The current review emphasizes cytomorphologic features, differential diagnosis, potential pitfalls associated with these lesions.Seven hundred seventy-nine percutaneous fine-needle aspiration (FNA) specimens were retrieved from cytopathology files over period 5 years....
Fine-needle aspiration biopsy (FNA) has been successful in diagnosing epithelial lesions of the breast. Its role evaluation spindle cell and mesenchymal breast, which include a variety benign malignant conditions, is less clear. This article discusses cytologic features differential diagnosis these lesions, as well potential diagnostic pitfalls associated with them.FNAs or component was key dominant feature, were retrieved. Fibroadenomas without cellular stroma typical lipomas...
Fine-needle aspiration biopsy (FNA) is an accurate and cost-effective procedure for evaluating salivary gland lesions. Lymphoproliferative lesions may manifest as enlargement. We report our experience with 43 cases of reactive neoplastic lymphoproliferative the glands evaluated by FNA, including 23 lymphoid hyperplasia 20 processes. The latter included 2 multiple myelomas 18 non-Hodgkin lymphomas (small lymphocytic lymphoma/chronic leukemia, 1; small cleaved cell lymphoma,...
Research Articles| April 19 2011 Clinical Significance of Atypical Glandular Cells Undetermined Significance: A Follow-up Study from an Academic Medical Center Subject Area: Pathology and Cell Biology David C. Chhieng; Chhieng From the Department Pathology, New York University Center, York, U.S.A. Search for other works by this author on: This Site PubMed Google Scholar Paul A. Elgert; Elgert Joan F. Cangiarella; Cangiarella Jean-Marc Cohen Acta Cytologica (2000) 44 (4): 557–566....
Background The management of high‐risk human papillomavirus (HR‐HPV)–related oropharyngeal head and neck squamous cell carcinomas (HNSCCs) are distinct from HNSCC linked to smoking alcohol use. HR‐HPV–positive frequently presents as a cervical lymph node metastasis. Because fine‐needle aspiration (FNA) is often the initial diagnostic procedure, evaluating HR‐HPV status in cytology specimens important. overexpression p16 surrogate for HR‐HPV; however, evaluation FNAs remains controversial....
Although two-thirds of tumors occurring in the central nervous system (CNS) are primary neoplasms, only 10% positive cerebrospinal fluid (CSF) specimens from CNS tumors. In this study, we reviewed cytologic findings 21 CSF A computer search identified cases patients with archives. Follow-up included review medical charts and histologic correlation. The were 20 (9 females 11 males). Their ages ranged 6-83 yr, old a mean 30 yr. 9 medulloblastomas, 7 gliomas (3 glioblastoma multiformes, 2...
Fine-needle aspiration (FNA) biopsy can accurately diagnose epithelial lesions of the salivary gland. Its role in evaluation gland containing a significant spindle cell component is less clear. We describe cytologic features 25 and discuss differential diagnosis potential diagnostic pitfalls. Twenty-five smears (3.0%) or mesenchymal were identified out 844 FNAs performed over 5-year period. These from patients. The classified into three categories: 1) reactive inflammatory conditions,...
Peripheral T-cell lymphoma (PTCL) accounts for 10-20% of all non-Hodgkin lymphomas in the United States. In this study, authors reviewed cytologic and immunophenotypic findings 33 fine-needle aspirations (FNAs) PTCL.Thirty-three FNAs from 26 patients (12 females 14 males) with PTCL were identified during 1991-1999. The patients' age ranged 19 to 96 years. Immunophenotyping was performed 24 cases by using either flow cytometry (FC; 21 cases) or immunocytochemistry (IC; 3 cases). Follow-up...
The presence of lymph node metastases in patients with malignant melanoma implies a significant decrease survival. authors investigated the efficacy fine-needle aspiration biopsy (FNAB) diagnosis metastatic 115 and clinically suspicious regional nodes.One hundred thirty-three FNABs were performed by cytopathologists after referral from surgeons or oncologists using 25-gauge 27-gauge needle.The cytologic was negative 35, atypical 1, 2, positive for 95. Regional dissections 78 patients. Of...
Diagnosis of non-Hodgkin's lymphomas based on cytologic evaluation fine-needle aspirates and body cavity fluids has gained increasing acceptance. However, the accurate diagnosis classification low- intermediate-grade B-cell with a predominant small-cell population still present diagnostic challenge. In this study, we reviewed cytology immunophenotype 56 cases composed predominantly small cells, histologic correlation in all cases. These consisted 23 lymphocytic (SLL), 15 follicular center...
BACKGROUND Hemangiopericytoma (HPC) is a relatively rare neoplasm, accounting for approximately 2.5% of all soft tissue tumors. Its histopathology has been well documented but to the authors' knowledge reports regarding its fine-needle aspiration (FNA) cytology rarely are encountered. In current study authors report cytologic findings in FNA specimens from nine confirmed cases HPC and attempt correlate features with biologic outcomes. METHODS was performed or without radiologic guidance....
Tattoo Pigment Mimicking Axillary Lymph Node Calcifications on MammographyMolly M. Honegger1, Stephen Hesseltine2, Joshua D. Gross1, Cory Singer1 and Jean-Marc Cohen3Audio Available | Share
Fine-needle aspiration (FNA) has been increasingly utilized as a diagnostic tool in evaluating salivary gland masses, primarily to differentiate nonneoplastic from neoplastic lesions. Patients infected with human immunodeficiency virus (HIV) frequently present In this study, we reviewed the cytology of lesions HIV-infected patients and assessed value FNA diagnosis patients. One hundred three FNAs 78 (63 males 15 females) were included our study. The patients' ages ranged 7-65 yr, mean age...
We report the cytologic findings of a case Rosai-Dorfman disease breast in 52-year-old diabetic woman, initially sampled by fine-needle aspiration biopsy (FNA). The patient presented with 2-week history 3 × 2 cm nodule mid–upper area left breast. A mammogram taken 6 months prior was negative. FNA smears demonstrated lymphocytes, plasma cells, and large pale enlarged irregular nuclei, admixed fragments fibrous tissue calcific debris. Lymphophagocytosis (emperipolesis) scarce. Our diagnosis...
The Bethesda System recommends qualifying atypical glandular cells with regard to their possible origin: endocervical versus endometrial. This study was undertaken determine the clinical significance of undetermined that favor an endometrial origin (AGUS-EM).A computer search identified 62 cervicovaginal smears (5.25% all classified as AGUS) a diagnosis AGUS-EM in files Shared Cytopathology Laboratory New York University Medical Center/Bellevue Hospital Center between January 1995 and...
Abstract: A case of postlactational microcalcifications is reported. 42-year-old woman presented for screening mammography 2 months after completion breast-feeding. Comparison to her pregravid mammogram revealed the appearance multiple groups indeterminate bilaterally (BIRADS IV). She underwent bilateral stereotactic core biopsies representative areas, yielding benign pathology. There have been anecdotal accounts and five reported cases lactational in radiology literature. We discuss...
Metastases to the breast from extramammary primary malignancies, including renal adenocarcinoma, are rare. Fine-needle aspiration biopsy (FNA) is a useful, noninvasive, and rapid procedure evaluate these mammary lesions. This study describes cytomorphology of 3 cases renal-cell adenocarcinoma metastatic breast. All patients had prior history treated with radical nephrectomy, they presented solitary mass. The cytologic findings showed irregular clusters dispersed single cells eccentric nuclei...