A5042811107- Ginseng Biological Effects and Applications
- Endometriosis Research and Treatment
- Endometrial and Cervical Cancer Treatments
- Protein Tyrosine Phosphatases
- Ovarian cancer diagnosis and treatment
- Bone Metabolism and Diseases
- Ovarian function and disorders
- Phytochemistry and Bioactive Compounds
- Lipid metabolism and disorders
- Cancer, Lipids, and Metabolism
- Cancer-related molecular mechanisms research
- Medicinal Plant Pharmacodynamics Research
- Traditional Chinese Medicine Analysis
Shanghai University of Traditional Chinese Medicine
2022-2024
Shanghai Traditional Chinese Medicine Hospital
2021-2024
Creative Commons
2021
National Natural Science Foundation of China
2021
Weatherford College
2021
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of childbearing age. Cryptotanshinone (CRY) has been shown to be effective reversing reproductive disorders, but whether it can used treatment polycystic remains unclear. We aimed explore mechanism cryptotanshinone driven via regulating ferroptosis. A rat model PCOS was established by daily injection human chorionic gonadotropin and insulin for 22 days. An vitro ischemia-reperfusion (IR) granulosa cells...
Polycystic ovary syndrome (PCOS) is a common disease affecting women of reproductive age; there need for interventions to address this condition. Herein, the network pharmacology approach was used explore potential combining Morindae Officinalis Radix (Bajitian) and Salviae (Danshen) treating PCOS. The bioactive ingredients Bajitian-Danshen pair were identified predicting therapeutic target genes. Genes related PCOS predicted by keyword search from various databases intersected with targets...
Polycystic ovary syndrome (PCOS) constitutes an endocrine and metabolic disorder characterized by hyperandrogenemia, ovulation disorders, polycystic ovary. Existing therapy is low efficacy has significant side effects. In traditional Chinese medicine, tanshinone was used for PCOS women. Here, we will investigate the safety, as well of in treating syndrome.Two researchers independently research eligible randomized controlled trials 6 repositories: PubMed, CINAHL, Web Science, EMBASE, China...