A5033890258- CAR-T cell therapy research
- Cancer-related molecular mechanisms research
- Nanowire Synthesis and Applications
- Cardiac Imaging and Diagnostics
- Ferroptosis and cancer prognosis
- MicroRNA in disease regulation
- Advanced biosensing and bioanalysis techniques
- Biomarkers in Disease Mechanisms
- Cardiovascular Disease and Adiposity
- RNA modifications and cancer
- Circular RNAs in diseases
- Viral Infectious Diseases and Gene Expression in Insects
- NF-κB Signaling Pathways
- Medicinal Plant Extracts Effects
- Pancreatic function and diabetes
- Sarcoidosis and Beryllium Toxicity Research
- Animal Diversity and Health Studies
- Turtle Biology and Conservation
- Vasculitis and related conditions
- Viral-associated cancers and disorders
- Infective Endocarditis Diagnosis and Management
- Radiomics and Machine Learning in Medical Imaging
- Boron Compounds in Chemistry
- COVID-19 and healthcare impacts
- Nanoparticle-Based Drug Delivery
Hamedan University of Medical Sciences
2014-2025
Shahid Sadoughi University of Medical Sciences and Health Services
2024-2025
Qom University of Medical Science and Health Services
2024
Shahid Beheshti University of Medical Sciences
2023
Taleghani General Hospital
2023
Creative Commons
2023
Advanced Neural Dynamics (United States)
2020
Golestan University
2019
Abstract In recent years, the field of cancer treatment has witnessed remarkable breakthroughs that have revolutionized landscape care for patients. While traditional pillars such as surgery, chemotherapy, and radiation therapy long been available, a cutting-edge therapeutic approach called CAR T-cell emerged game-changer in treating multiple myeloma (MM). This novel method complements options like autologous stem cell transplants immunomodulatory medications, proteasome inhibitors, by...
Investigating the relationship between severity of coronary artery disease and inflammatory factors MHR, PHR, NHR, IL-25
Colorectal cancer (CRC) liver metastasis accounts for the majority of fatalities associated with CRC. Early detection is crucial improving patient outcomes but can be delayed due to a lack symptoms. In this research, we aimed investigate CRC metastasis-related biomarkers by employing machine learning (ML) approach and experimental validation. The gene expression profile patients was obtained using GSE41568 dataset, differentially expressed genes between primary metastatic samples were...
Introduction: In the present study, we evaluated impact of empagliflozin on serum levels oxidative stress parameters in individuals with type 2 diabetes (T2DM) who also suffer from heart failure Reduced Ejection Fraction (HFrEF). Methods: this prospective, single-center clinical trial, 80 patients T2DM and HFrEF, stabilized guideline-directed therapy classified as New York Heart Association functional (NYHA) classes II or III, were randomized to receive either (10 mg/daily) a matching...
Background: The discharge of uncomplicated patients with ST-segment-elevation myocardial infarction (STEMI) within 48 to 72 hours has been proven safe and feasible. safety feasibility the very early (≤48 h) such patients, especially during COVID-19 pandemic limited bed availability infection risk, have yet be evaluated. Methods: In this cohort study on 108 STEMI who presented Farshchian Heart Center between February May 2020, 30 received fibrinolysis 78 were scheduled for emergent coronary...
Targeted Alpha Therapy (TAT) is considered an evolving therapeutic option for cancer cells, in which a carrier molecule labeling with α-emitter radionuclide make the bond specific functional or molecular target. α-particles high Linear Energy Transfer (LET) own increased Relative Biological Effectiveness (RBE) over common β-emitting radionuclides. Normal tissue toxicity due to non-specific uptake of mother and daughter radionuclides seems be main conflict clinical applications. The present...
Objective: Ferroptosis is a form of programmed cell death characterized by the irondependent accumulation lipid peroxides, leading to membrane damage and rupture. Several lines evidence suggest that ferroptosis may contribute pathogenesis severity COVID- 19. This study aimed measure iron metabolism peroxidation markers in COVID-19 patients establish direct link between COVID-19. Methods: In present cross-sectional study, serum levels hemoglobin (Hb), ferritin, iron, total binding capacity...
Abstract Objective Given the incidence of epilepsy and adverse effects unconventional antiepileptic medicines, there is a need for novel medical treatment strategy epileptic patients. Materials Methods The current study involved selection 80 male mice, which were then separated into 10 experimental groups: pentylenetetrazol (PTZ), negative control received normal saline, Lavandula officinalis in two doses 200 400 mg/kg, L. mg/kg 1400 w, 7-NI, diphenylene iodonium chloride (DPI),...
Background: The coronary artery calcium score has been established as a highly specific feature of atherosclerosis. present study aimed to assess the possible association risk factors involving atherosclerosis with calcification (CAC) scores using computed tomographic angiography (CCTA). Methods: cross-sectional study, performed on 252 patients in need CCTA during April 2019 and September at Farshchian hospital Hamadan, Iran. demographic information were acquired from files patients....
Granulomatosis with polyangiitis (GPA) is a necrotizing vasculitis. The etiology of the disease not completely known. In this report, we describe 47-year-old male who presented ongoing dyspnea. He known case GPA for 3 years based on skin biopsy and positive antineutrophil cytoplasmic antibody. electrocardiogram showed changes suggestive myocarditis. A transthoracic trans esophageal echocardiogram revealed left ventricular systolic dysfunction, thickened atrial wall vegetation mitral valve....