A5004181782- Advanced Drug Delivery Systems
- Drug Solubulity and Delivery Systems
- Anesthesia and Pain Management
- Synthesis and properties of polymers
- Anorectal Disease Treatments and Outcomes
- Adsorption, diffusion, and thermodynamic properties of materials
- biodegradable polymer synthesis and properties
- Analytical Methods in Pharmaceuticals
- Surgical Sutures and Adhesives
Gdańsk Medical University
2008-2024
The production of orodispersible films (ODFs) with suspended insoluble drug substances is still a challenge, mainly due to the difficulty associated achieving proper homogeneity and mechanical properties films. Hypromellose (HPMC) mixture polyvinyl alcohol (AP) povidone (PVP) were compared in terms their suitability for ODFs incorporating micronized loratadine (LO) concentration range 10%-40%. In planetary mixer (Thinky), uniform dispersion LO an aqueous viscous casting solution was...
The aim was to evaluate ointments for local treatment of anal fissures. Nitroglycerin (NTG) complexed with β-cyclodextrin (β-CD) provide prolonged NTG release, the intention decreasing systemic drug absorption and thus reducing side effects.Gels, creams anhydrous water-emulsifying (AWE) ointment NTG-CD were compared preparations containing uncomplexed (diluted crospovidone, NTG-cP). in-vitro release ex-vivo skin studied.The prolonged-release complex formulated using AWE base or w/o cream...