A5035452865- Wound Healing and Treatments
- 3D Printing in Biomedical Research
- Immune Response and Inflammation
- Body Contouring and Surgery
- Additive Manufacturing and 3D Printing Technologies
- thermodynamics and calorimetric analyses
- Drug-Induced Hepatotoxicity and Protection
- Energy and Environment Impacts
- Force Microscopy Techniques and Applications
- Air Quality and Health Impacts
- Immune cells in cancer
- Reconstructive Surgery and Microvascular Techniques
- Epigenetics and DNA Methylation
- Genomics, phytochemicals, and oxidative stress
- Gut microbiota and health
- Cellular Mechanics and Interactions
- Diet, Metabolism, and Disease
- Liver Disease Diagnosis and Treatment
- Breast Implant and Reconstruction
- Traffic and Road Safety
- Anatomy and Medical Technology
Emory University
2018-2021
Committee on Publication Ethics
2021
Icahn School of Medicine at Mount Sinai
2021
The Wallace H. Coulter Department of Biomedical Engineering
2018-2020
Georgia Institute of Technology
2018-2020
Abstract Given that dysregulation of mechanics contributes to diseases ranging from cancer metastasis lung disease, it is important develop methods for screening the efficacy drugs target cellular forces. Here, nanoparticle‐based tension sensors are used quantify mechanical response individual cells upon drug treatment. As a proof‐of‐concept, activity bronchodilators tested on human airway smooth muscle derived seven donors, four which asthmatic. It revealed isolated asthmatic donors exhibit...
BACKGROUND AND OBJECTIVES: The goal of this study is to evaluate in a time-series the short-term effects particulate matter-2.5exposure on respiratory emergency visits six central-southern Chilean cities highly contaminated by wood smoke.METHODS: Association was assessed using both distributed lag linear and non-linear Poisson models constrained 7-day period, adjusting for temporal trends meteorological variables stratifying seasonally into cold warm periods.FINDING: results showed that...
The objective of this study was to evaluate long-term outcomes and weight loss after panniculectomy.A retrospective chart review performed on 225 consecutive patients who had undergone panniculectomy from 2002 2020. Demographic variables including smoking status, medical comorbidities, prior history loss/bariatric surgery were collected for 173 patients. Preoperative postoperative body mass index (BMI) calculated in addition outcomes.The population 85% female with a mean age 57 years an...
The gut microbiome is a dynamic community of microorganisms within the intestinal lumen. Many studies have suggested role for gut-resident microbes in modulating host health, however mechanisms by which these communities impact systemic physiology remain largely unknown. In this study, metabolomic and transcriptional profiling germ-free conventionalized mouse liver revealed an upregulation Nrf2 antioxidant xenobiotic response microbiome-replete animals. Using Drosophila-based screening...
OBJECTIVES/SPECIFIC AIMS: Scavenger receptor (SR) surface proteins are highly conserved motifs and implicated in the uptake of nanotherapies. Gold nanoparticles functionalized with DNAzymes (DzNP) represent a promising novel nanotherapy for lung diseases such as asthma, particularly because they can be delivered directly to lung. Our lab has been studying therapeutic potential DzNP targeting GATA-3, master transcription factor regulating Th2 inflammation. Although nanoparticle through...
Purpose - Wound care following surgical procedures involves careful management, reducing risk of infection, and maximizing tissue oxygenation. Even with new strides in biological synthetic products, achieving adequate wound remains an important topic interest. In this study, we develop injectable hydrogel to promote resolution while increasing polarization immune subsets towards healing phenotypes. These poly(ethylene glycol)-maleimide (PEG-MAL) hydrogels are capable locally delivering...