- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and biological activity
- Metal complexes synthesis and properties
- Chronic Lymphocytic Leukemia Research
- Chemical synthesis and alkaloids
- Research in Cotton Cultivation
- Asymmetric Synthesis and Catalysis
- Lipid metabolism and biosynthesis
- Free Radicals and Antioxidants
- Biochemical and Molecular Research
- Advances in Cucurbitaceae Research
- Alkaloids: synthesis and pharmacology
- Peptidase Inhibition and Analysis
International Center for Chemical and Biological Sciences
2020
University of Karachi
2020
COMSATS University Islamabad
2018-2019
Abbottabad University of Science and Technology
2019
University of Lagos
2018
Background: A number of synthetic scaffolds, along with natural products, have been identified as potent antioxidants. The present study deals the evaluation varyingly substituted, medicinally distinct class compounds “chalcones and bis-chalcones” for their antioxidant potential. Methods: In vitro radical scavenging activities were performed on a series chalcones 1- 13 bis-chalcones 14-18. Results: All molecules 1-18 revealed pronounced 2-diphenyl-1-picrylhydrazyl (DPPH) 2,2ʹ-...
Reserpine is an indole alkaloid, antipsychotic, and antihypertensive drug that has been used for the control of high blood pressure relief psychotic symptoms. It was first isolated in 1952 from dried root Rauwolfia serpentina whose molecular structure established 1953 natural configuration published 1955. The total synthesis reserpine reported by Woodward 1958. This review article updates current multistep synthetic approaches toward product its analogues.