A5048543070- Flowering Plant Growth and Cultivation
- Genetic Neurodegenerative Diseases
- Mitochondrial Function and Pathology
- Plant Physiology and Cultivation Studies
- Plant Pathogens and Fungal Diseases
- Genetics and Plant Breeding
- Powdery Mildew Fungal Diseases
- Banana Cultivation and Research
- Growth and nutrition in plants
- Plant Genetic and Mutation Studies
- Plant Virus Research Studies
- Plant pathogens and resistance mechanisms
- Agricultural pest management studies
- Plant Reproductive Biology
- Agronomic Practices and Intercropping Systems
- Botany and Plant Ecology Studies
- Polysaccharides Composition and Applications
- RNA modifications and cancer
- Agricultural Science and Fertilization
- DNA Repair Mechanisms
- Advances in Cucurbitaceae Research
- Agricultural Practices and Plant Genetics
- GDF15 and Related Biomarkers
- Horticultural and Viticultural Research
- Plant tissue culture and regeneration
All India Institute of Medical Sciences
2011-2023
Centre hospitalier de l'Université Laval
2012
Université Laval
2012
National Brain Research Centre
2008
Indian Agricultural Research Institute
1968-1977
Growing evidence suggests that galectin-3 is involved in fine tuning of the inflammatory responses at periphery, however, its role injured brain far less clear. Our previous work demonstrated upregulation and coexpression IGF-1 a subset activated/proliferating microglial cells after stroke. Here, we tested hypothesis plays pivotal mediating injury-induced activation proliferation. By using knock-out mouse (<i>Gal-3KO</i>), targeted disruption gene significantly alters microglia induces...
OBJECTIVES; To evaluate therapeutic efficacy of arctigenin in an experimental model Japanese encephalitis (JE).Four- to 5-week-old BALB/c mice either sex were infected intravenously with lethal dose 3 x 10(5) pfu virus (JEV). By the 9th day post-infection, all untreated animals succumbed infection. Arctigenin was dissolved DMSO at a concentration 0.5 mg/mL and stored 4 degrees C. After one following inoculation, given intraperitoneally, twice daily (10 mg/kg body weight) for next 7...
1. Five species of Abelmoschus-A. esculentus (Linn.) Moench. (the cultivated species), A. ficulneus (L.) W. & A., manihot Medik., Medik. var. pungens (Roxb.) Hochr., and tuberculatus-have been studied morphologically in interspecific hybridization. These studies have confirmed the view that these constitute a distinct taxonomic unit. 2. Results show tuberculatus sp. nov. is more nearly related to than any other species, follows it. rightly appears be variety as adopted by Hochreutiner. is,...
DNA triplet repeat expansion-associated ataxias, Friedreich's ataxia, and different types of spinocerebellar ataxias (SCAs) are progressive multisystem neurodegenerative disorders. The diagnosis this wide group inherited is essentially based on clinical findings. Cell-free circulating in plasma has been considered as a powerful tool prognosis several human diseases. In the present study, clinically suspected patients were assessed International Co-operative Ataxia Rating Scale further...
Resistance to blackrot was found be dominant over susceptibility and governed by polygenes. The dominance component of variation greater than the additive in almost all crosses. Breeding methods adopted for incorporating genes resistance into susceptible varieties like Snowball are suggested.
Friedreich's ataxia (FRDA) is an autosomal recessive ataxia, characterized by progressive gait limb dysarthria, and areflexia associated with diabetes hypertrophic cardiomyopathy. The primary cause of FRDA the presence expanded DNA triplet (GAA) repeats in first intron fxn gene on chromosome 9q13. inhibit expression protein frataxin, which leads to neuronal degeneration. aim study was identify differentially expressed plasma proteins patients for their diagnostic/prognostic applications....
Breast cancer metastases are most commonly found in bone, an indication of poor prognosis. Pathway-based biomarkers identification may help elucidate the cellular signature breast metastasis further characterizing etiology and promoting new therapeutic approaches. We extracted gene expression profiles from mouse macrophages GEO dataset, GSE152795 using GEO2R webtool. The differentially expressed genes (DEGs) were filtered by log2 fold-change with threshold 1.5 (FDR < 0.05). STRING database...
<b><i>Background:</i></b> Spinocerebellar ataxia type 2 (SCA2) is an autosomal-dominant hereditary characterized by progressive gait and limb ataxia, dysarthria, slow saccades, neuropathy dementia. The expansion of trinucleotide CAG repeats in the coding region <i>ATXN-2</i> gene leads to expanded polyglutamine stretch mutated protein which causes neuronal death. <b><i>Objective:</i></b> In this study, we investigated blood plasma...
Synopsis The local lesion type of resistance to wheat streak‐mosaic virus exhibited by an intermediate Agrotricum (2 n = 56) is conditioned factors located on one or more chromosomes non‐homologous common (2n 42), chromosomes. Therefore, the transfer this from hybrid would appear be most difficult at least with particular strain used.
Alzheimer’s disease (AD) is a neurodegenerative disorder that characterized by progressive loss of cognitive functions at higher level than normal aging. Although the apolipoprotein (APOE) gene major risk factor in developing AD, other genes have also been reported to be linked with complex phenotypes. Therefore, this genome-wide expression study explored differentially expressed as possible novel biomarkers involved AD. The mRNA dataset, GSE28146, containing 15 sample data composed 7 AD...
Methylation of adenosines at N6 position (m6A) is the most frequent internal modification in mRNAs human genome and attributable to diverse roles physiological development, pathophysiological processes. However, studies on role m6A neuronal development are sparse not well-documented. The detection remains challenging due its inconsistent pattern less sensitivity by current techniques. Therefore, we applied a sliding window technique identify consensus site (5'-GGACT-3') n ≥ 2 annotated all...
Acute myocardial infarction (AMI) is a severe disease with elevated morbidity and mortality rate worldwide. This attributed to great losses of cardiomyocytes, which can trigger the alteration gene expression patterns. Although several attempts have been made assess AMI biomarkers, date their role in rescuing injury remains unclear. Therefore, current study investigated three independent microarray-based datasets from patients (n = 85) age–sex-matched healthy controls 70), identify novel...