- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Anesthesia and Pain Management
- Nausea and vomiting management
- Pediatric Pain Management Techniques
- Anesthesia and Neurotoxicity Research
- Anesthesia and Sedative Agents
- Enhanced Recovery After Surgery
- Platelet Disorders and Treatments
- Trauma Management and Diagnosis
- Disaster Response and Management
- Pharmacogenetics and Drug Metabolism
- Pleural and Pulmonary Diseases
- Traumatic Ocular and Foreign Body Injuries
- Heparin-Induced Thrombocytopenia and Thrombosis
- COVID-19 epidemiological studies
- Neuropeptides and Animal Physiology
- Central Venous Catheters and Hemodialysis
- Parvovirus B19 Infection Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Airway Management and Intubation Techniques
- Immune Cell Function and Interaction
- Pain Management and Opioid Use
- COVID-19 and healthcare impacts
Auckland City Hospital
2024
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2020
Azienda Regionale Emergenza Urgenza
2020
University of Geneva
2019
University of Milano-Bicocca
2015-2018
Ospedale Maggiore
2017
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2017
Azienda Ospedaliera San Gerardo
2014-2016
Summary Background Children commonly display early postoperative negative behavior (e‐ PONB ) after general anesthesia, which includes emergence delirium ( ED ), discomfort, temperament, and pain. However, it is often difficult for the caregiver to discriminate between various aspects of e‐ . Objective This prospective observational study evaluates possibility distinguish pain in young children using validated pediatric scales phase. Methods Following institutional approval written consent,...
Abstract Objective To quantify how the first public announcement of confirmed coronavirus disease 2019 (COVID‐19) in Italy affected a metropolitan region's emergency medical services (EMS) call volume and rapid introduction alternative procedures at safety answering point (PSAP) managed system resources. Methods PSAP processes were modified over several days including (1) referral non‐ill callers to health information centers; (2) algorithms for detection, isolation, or hospitalization...
Background . Intraperitoneal nebulization of ropivacaine reduces postoperative pain and morphine consumption after laparoscopic surgery. The aim this multicenter double-blind randomized controlled trial was to assess the efficacy different doses dose-related absorption when nebulized in peritoneal cavity during cholecystectomy. Methods Patients were receive 50, 100, or 150 mg 1% by through a nebulizer. Morphine consumption, intensity abdomen, wound shoulder, time unassisted ambulation,...
Rationale: We present a case of hemophagocytic lymphohistiocytosis (HLH) with severe pulmonary complication and acute respiratory distress syndrome (ARDS) hospitalized in our intensive care unit (ICU) 2014; distinctive trait this has been the challenging diagnosis, bone marrow biopsy always negative, ARDS hypertension, ferritin temporal kinetics that precisely followed clinical course disease. Patient concerns: A 32-year-old woman from Philippines first diagnosed upper airway infection, was...
We report the case of a woman who developed post-transfusion purpura following complicated cardiac surgery requiring multiple blood product transfusions and extracorporeal life support. This highlights challenges managing thrombocytopenia in patients supported with prolonged mechanical cardiovascular renal support ongoing transfusion requirements. The differential diagnoses are broad, varied may overlap. Whilst is very rare, clinical signs prompt consideration further specific diagnostic...
Adding cyclic short sustained inflations (sigh) to assisted ventilation yields optimizes lung recruitment, decreases heterogeneity and reduces inspiratory effort in patients with acute hypoxemic respiratory failure (AHRF). These findings suggest that adding sigh pressure support (PSV) might decrease the risk of injury, shorten weaning improve clinical outcomes. Thus, we conceived a pilot trial test feasibility PSV (the PROTECTION study). is an international randomized controlled will be...
Although PEEP and inversed I:E ratio have been shown to improve gas exchange in ARDS, both can adversely affect systemic hemodynamics cerebral perfusion. The goal of this study was assess how changes oxygenation perfusion normal injured lung. Eight anesthetized Chinchilla-Bastard rabbits were ventilated at baseline with pressure-regulated volume control mode, VT = 6 ml/kg, cmH2O, FIO2 0.4; respiratory rate set for ETCO2 5.5%, 1:2, 1:1 or 2:1 random order. Ultrasonic carotid artery flow (CF),...
Abstract: Blunt chest trauma is defined as a high energy injury to the thorax and its structures, it usually strong indicator of severe injury. Its clinical presentation can vary from rib fractures pneumothorax, hemothorax, lung soft tissue contusion; these lesions consequential pain predispose respiratory failure by compromising mechanics exacerbating pre-existing disease. This picture lead number complications, such pneumonia or ARDS, that have significant impact on patients' morbidity...
Prospective observacional study, approved by the institucional ethics committee • Inclusion criteria: patients undergoing urologic, gynecologic, plastic and general curative neoplastic surgery admitted at post anaesthetic care unit (PACU) Exclusion age < 18 years old inability to give informed consent Quality of Recovery 15 Score (QOR-15): on day before (T0) repeated it 24 hours after (T1) Poor quality recovery (PQR): defined as a QoR15 score lower than mean T1 minus 1 standard deviation...