- Nanoparticle-Based Drug Delivery
- Hepatitis C virus research
- Vestibular and auditory disorders
- Mobile Health and mHealth Applications
- RNA Interference and Gene Delivery
- Hepatitis B Virus Studies
- Electronic Health Records Systems
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Systems and Technology
- Radiation Dose and Imaging
- Nanoplatforms for cancer theranostics
- Clinical practice guidelines implementation
- Ophthalmology and Eye Disorders
- Primary Care and Health Outcomes
- Liver Disease Diagnosis and Treatment
- Opioid Use Disorder Treatment
- Radiology practices and education
- Lipid Membrane Structure and Behavior
- Patient Satisfaction in Healthcare
- Health Literacy and Information Accessibility
- Digital Mental Health Interventions
- Diabetes Management and Research
- Ultrasound in Clinical Applications
- Botulinum Toxin and Related Neurological Disorders
- Vector-borne infectious diseases
University of California, Davis
2010-2025
UC Davis Health System
2013-2024
University of California, Santa Barbara
2018-2023
University of California Davis Medical Center
2015-2022
Universities Space Research Association
1989-1993
Johnson Space Center
1991
National Aeronautics and Space Administration
1991
Importance The 21st Century Cures Act Final Rule mandates the immediate electronic availability of test results to patients, likely empowering them better manage their health. Concerns remain about unintended effects releasing abnormal patients. Objective To assess patient and caregiver attitudes preferences related receiving immediately released through an online portal. Design, Setting, Participants This large, multisite survey study was conducted at 4 geographically distributed academic...
Individually designed single-patient multi-crossover (n-of-1) trials can facilitate tailoring of treatments directed at various conditions, including chronic musculoskeletal pain (CMSP) but are potentially burdensome, which may limit uptake in research and practice. To determine whether patients randomized to participate an n-of-1 trial supported by a mobile health (mHealth) app would experience less improved global health, adherence, satisfaction, shared decision making compared with...
Poly(ethylene glycol) (PEG) is a polymer used widely in drug delivery to create "stealth" nanoparticles (NPs); PEG coatings suppress NP detection and clearance by the immune system beneficially increase circulation time vivo. However, PEGylation typically obstructs cell attachment uptake vitro compared uncoated equivalent. Here, we report on cationic liposome (CL) loaded with hydrophobic cancer paclitaxel (PTX) which (i.e., PEG-CLPTX NPs) unexpectedly enhances, rather than diminishes,...
There has been an exponential growth in the use of telemedicine services to provide clinical care, accelerated by COVID-19 pandemic. Clinical care delivered via become a major and accepted method health delivery for many patients. is urgent need understand quality environment. This American College Physicians position paper presents 6 recommendations ensure appropriate performance measures evaluate provided
Chronic pain is prevalent, costly, and clinically vexatious. Clinicians typically use a trial-and-error approach to treatment selection. Repeated crossover trials in single patient (n-of-1 trials) may provide greater therapeutic precision. N-of-1 are the most direct way estimate individual effects useful comparing effectiveness toxicity of different analgesic regimens. The goal PREEMPT study test 'Trialist' mobile health smartphone app, which has been developed make n-of-1 easier accomplish,...
Importance Patients have immediate access to test results in the patient portal, which can cause worry. Identifying behaviors associated with worry while awaiting may allow health systems support patients and reduce message volumes. Objective To describe characteristics of who refresh their portal measure association between behavior patient-initiated messaging. Design, Setting, Participants This retrospective cross-sectional study was performed at Vanderbilt University Medical Center, uses...
Background: Implementation of screening recommendations for chronic hepatitis B (CHB) among foreign-born persons at risk has been sub-optimal. The use alerts and reminders in the electronic health record (EHR) led to increased other common conditions. aim our study was measure effectiveness an EHR alert on implementation surface antigen (HBsAg) Asian Pacific Islander (API) patients.Methods: We used a novel technique identify API patients by self-identified ethnicity, surname, country origin,...
Abstract Background Proactive referrals through electronic orders (eReferrals) can increase patient connection with tobacco quitlines. More information is needed on “real-world” implementation of health record tools to promote cessation while minimizing provider burden. Objectives This paper examines the system an eReferral a quitline without best practice alerts in primary care, specialty, and hospital settings academic system. Methods prospective study state that was completed approach...
Background: The electronic health record (EHR) provides opportunity to improve and enhance appropriate test utilization through decision support. Electronic alerts in the order entry system can guide use. Few published reports have assessed impact of automated on compliance Pap ordering with screening guidelines. Methods: Programming rules for were developed within EHR (Epic, Madison, WI) University California, Davis Health System using American College Obstetrics Gynecology's 2009...
Abstract To measure the effect of an electronic health record (EHR) alert on chronic hepatitis B (CHB) screening among at-risk Asian and Pacific Islanders (API). API patients who had not yet completed surface antigen (HBsAg) testing were identified by a novel EHR-based population tool. At-risk in Cohort 1 (primarily privately insured) 2 (includes Medicare and/or Medicaid) randomized to activation their medical charts or not. In total, 8299 found be deficient HBsAg completion at baseline...
Abstract Objective: To evaluate the impact of implementing clinical decision support (CDS) tools for outpatient antibiotic prescribing in emergency department (ED) and clinic settings. Design: We performed a before-and-after, quasi-experimental study that employed an interrupted time-series analysis. Setting: The institution was quaternary, academic referral center Northern California. Participants: included prescriptions patients ED 21 primary-care clinics within same health system....