A5102012371- Drug-Induced Hepatotoxicity and Protection
- Acute Kidney Injury Research
- Lipoproteins and Cardiovascular Health
- Antiplatelet Therapy and Cardiovascular Diseases
- Crystallization and Solubility Studies
- Analytical Methods in Pharmaceuticals
- Liver Disease Diagnosis and Treatment
- Mast cells and histamine
- Diet and metabolism studies
- Sympathectomy and Hyperhidrosis Treatments
- Apelin-related biomedical research
- Inflammatory mediators and NSAID effects
- Pharmacological Effects of Natural Compounds
- Drug Solubulity and Delivery Systems
- Nuts composition and effects
- Antibiotics Pharmacokinetics and Efficacy
- Olfactory and Sensory Function Studies
- Diabetes Treatment and Management
- Migraine and Headache Studies
- Drug Transport and Resistance Mechanisms
- Coronary Interventions and Diagnostics
Cairo University
2016-2022
Jouf University
2022
The current work aimed to overcome the poor permeability and undesirable adverse effects of Zolmitriptan (ZMT) increase its efficacy in treatment acute migraine by exploiting synergistic effect essential oil, lavender, fabricate ZMT self-nanoemulsifying drug delivery systems (ZMT-SNEDDS).ZMT-SNEDDS were fabricated based on full factorial design (32) statistically assess impact oil surfactant concentrations nanoemulsion globule size, zeta potential percentage dissolution efficiency. An...
Context: Lornoxicam is a potent non-steroidal anti-inflammatory drug (NSAID). It shows limited solubility in the gastric pH, delayed bioavailability and pharmacodynamic effects with aggravated side (due to longer residence stomach wall).Objective: To enhance dissolution of lornoxicam fluid expectedly absorption pharmacological action, less ulcerogenic effects.Materials methods: Formulation immediate release (IR) liquitablets containing both liquid solid modulators (wetting agent,...
Background and Objective: Acetaminophen (APAP), is a commonly prescribed analgesic antipyretic drug in clinical practice.It has been reported that APAP overdose potentially induces hepatorenal damage experimental animals humans severe cases may lead to death.Acute renal failure -1-2% of patients because overdose.This study was intended explore the possible effects Acacia senegal, known as Arabic gum (AG) on paracetamol (N-acetyl-p-aminophenol, APAP)induced nephrotoxicity an albino rat...
Introduction Hypertensive Nephropathy (HN) is a state of renal damage due to chronic high blood pressure (BP). It widely spread disease increasing incidence [1]. Hypertension-induced injury attributed impaired autoregulation or complex interaction between ren