A5066084620- Metabolomics and Mass Spectrometry Studies
- Lung Cancer Treatments and Mutations
- Per- and polyfluoroalkyl substances research
- Metastasis and carcinoma case studies
- Vitamin D Research Studies
- Cancer, Hypoxia, and Metabolism
- Estrogen and related hormone effects
- Cancer-related Molecular Pathways
- Gastric Cancer Management and Outcomes
Huazhong University of Science and Technology
2022-2025
Tongji Hospital
2022-2023
This study employed computational biology approaches to investigate the interactions between per- and polyfluoroalkyl substances (PFAS) key colorectal cancer (CRC) proteins. The results indicate that PFAS may influence CRC progression by modulating multiple proteins, particularly glutathione S-transferase A1 (GSTA1). Computational analysis revealed 14 exhibits high binding affinity for GSTA1, occupying its glutathione-binding site. Further simulations confirmed stable of across different...
Colonic metastases of lung adenocarcinoma are extremely rare. Signet ring cell (SRCA) has not been described in patients with gastrointestinal metastasis adenocarcinoma. SRCA is a unique subtype strong invasion and poor prognosis, most found the due to metastases. This report describes rare case colonic from primary SRCA. A 64-year-old female was admitted Sun Yat-sen University Cancer Center for feeling nausea malaise. Following positron emission tomography CT (PET-CT) scan, widespread tumor...