Introduction Depression is one of the most incapacitating psychiatric diseases that disturb life millions people round globe. Its major causes include stressful events, bereavement, social abuses or certain biological and genetic factors with complex causal mechanisms. Higher salivary cortisol levels for a long period lead to dyslipidemias which increase body mass index (BMI), elevate adiposity waist-to-hip ratio (WHR). Such individuals high quartiles BMI have considerably higher risk...

Introduction: Diabetes mellitus (DM) poses a growing global health concern due to increasing prevalence, leading substantial economic burdens. While current therapeutic options control hyperglycemia, their side effects can reduce patient compliance. Canagliflozin, an SGLT-2 inhibitor and zinc supplementation have individually demonstrated potential in managing diabetes mellitus. Aims & Objectives: This study aimed assess the synergistic of Zinc Sulphate Canagliflozin combination therapy...

Introduction: Though highly effective as an anti-tuberculosis drug, Pyrazinamide has a notable side effect of causing hepatic toxicity and damaging the liver architecture. Nigella sativa been shown to have hepatoprotective effects should be tested against induced damage. Objective: To determine protective role (NS) seeds in preserving histoarchitectural changes by (PZA) mice. Materials & Methods: It was laboratory based randomized control trial conducted on forty male albino mice divided...

Background: Pelvic pain around the time of mensturation without any identifiable pathologic lesion present from menarche is called primary dysmenorrhea. The believed to be related prostaglandin (PG). Women with dysmenorrhoea have a relatively high concentration PGF 2 alpha in menstrual fluid and suppression PG synthesis has become main treatment. Aim: To compare mean reduction patients presenting dysmenorrhea given vitamin E & Mefenamic acid versus alone. Results: It was randomized...

ABSTRACT
 Background: Central obesity a worldwide metabolic and cosmetic problem poses significant health risk. Ajwa date seed has antioxidant property its high fiber content may prevent fat absorption reduce deposition.
 Objective: To evaluate the effect of powder on visceral depots inflammatory response in fed Sprague Dawley female rats.
 Methodology: Thirty-six healthy rats four weeks age were divided into three groups followed for 12 weeks. Group A (normal control)...

Purpose: The aim of this study was to find out Bacterial etiology and antimicrobial susceptibility pattern bacteria causing infective keratitis at a tertiary care hospital LahoreStudy Design:Descriptive cross sectional studyStudy Place Study Period: PGMI/AMC/LGH, Lahore, in 2015 - 2018. Sample Collection: Non-probability convenience samplingMaterial Methods: corneal scrapings taken by the ophthalmologist immediately inoculated on Chocolate agar, Blood agar MacConkay culture plates with help...

Introduction: Hyperuricemia results in an increased level of blood uric acid, a prerequisite gout. Commonly prescribed agents for the treatment hyperuricemia include allopurinol, febuxostat, and probenecid. Multiple adverse effects like hypersensitivity, gastrointestinal upsets hepatotoxicity limit their use.
 Aims & Objectives: To evaluate serum acid lowering Nigella sativa seeds on pyrazinamide induced mice.
 Place duration study: This study was carried out at research...

Objectives: This study was done to observe the effect of Enterococcus faecium SF68 and Saccharomyces boulardii in acute severe diarrhea infants. Methods: It a single blind, randomized controlled clinical trial Children Hospital, Lahore. The infants were selected between 6 months 12 age. All suffering from with dehydration. Total 105 randomly divided into three groups having 35 each group. Infants group A received standard treatment diarrhea. B C respectively twice daily for five days along...

Introduction: The Chemotherapy-Induced Anemia (CIA) is a complex phenomenon impacted by many treatments and patient related variables. Some variations within CIA are type of chemotherapeutic agent, dose schedule administration as well stage cancer, time intervention, age, gender, nutritional status renal function. variety presentation symptomatology in very thought-provoking while setting up widespread measures to oversee ideal treatments. This study will be focused on protective role apple...

Introduction: Apple peel is rich in many bioactive compounds and has been studied for its beneficial effects protective role multiple disorders, but effect on blood cells bone marrow needs to be investigated.
 Aims & Objectives: To determine the of apple extract peripheral prednisolone treated mice.
 Place duration study: Pharmacology Department Post Graduate Medical Institute Pathology Fatima Jinnah University, Lahore from June September, 2016.
 Material Methods: Forty...